SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ur2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 ALA A 272
VAL A 321
TRP A 305
 None
None
P5F  A1001 (-3.7A)
 0.89A 1av2A-5ur2A:
undetectable
1av2B-5ur2A:
undetectable		 1av2A-5ur2A:
2.82
1av2B-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 TRP A 305
ALA A 272
VAL A 321
 P5F  A1001 (-3.7A)
None
None
 0.91A 1av2C-5ur2A:
undetectable
1av2D-5ur2A:
undetectable		 1av2C-5ur2A:
2.82
1av2D-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 5 GLY A  12
LEU A 442
ARG A 356
VAL A 355
 None
 1.07A 1ekjF-5ur2A:
2.3
1ekjG-5ur2A:
undetectable		 1ekjF-5ur2A:
12.23
1ekjG-5ur2A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 LEU A 419
ARG A 417
LEU A 414
PHE A  52
PHE A  54
 None
 1.26A 1g5yC-5ur2A:
undetectable		 1g5yC-5ur2A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 9 GLY A 930
ALA A 781
THR A 902
SER A 779
ALA A 780
 None
 1.27A 1gtnQ-5ur2A:
undetectable
1gtnR-5ur2A:
undetectable		 1gtnQ-5ur2A:
6.57
1gtnR-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.13A 1gtnU-5ur2A:
undetectable
1gtnV-5ur2A:
undetectable		 1gtnU-5ur2A:
6.57
1gtnV-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 933
SER A 779
ALA A 780
GLY A 765
ALA A 781
 None
 0.96A 1gtnL-5ur2A:
undetectable
1gtnV-5ur2A:
undetectable		 1gtnL-5ur2A:
6.57
1gtnV-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 775
VAL A 820
ALA A 781
SER A 782
LEU A 798
 None
 1.37A 1kiaD-5ur2A:
4.9		 1kiaD-5ur2A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 876
VAL A 820
ALA A 781
SER A 782
LEU A 798
 None
 1.36A 1kiaD-5ur2A:
4.9		 1kiaD-5ur2A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A 350
ALA A 336
ILE A 343
PRO A 348
 None
 1.14A 1oniA-5ur2A:
undetectable
1oniB-5ur2A:
undetectable		 1oniA-5ur2A:
10.16
1oniB-5ur2A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A 844
ALA A 802
ILE A 807
PRO A 857
 None
 1.14A 1oniA-5ur2A:
undetectable
1oniB-5ur2A:
undetectable		 1oniA-5ur2A:
10.16
1oniB-5ur2A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 6 PHE A 844
ALA A 802
ILE A 807
PRO A 857
 None
 1.06A 1oniH-5ur2A:
undetectable
1oniI-5ur2A:
undetectable		 1oniH-5ur2A:
10.16
1oniI-5ur2A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 7 ILE A 343
PRO A 348
PHE A 350
ALA A 336
 None
 1.03A 1oniG-5ur2A:
undetectable
1oniI-5ur2A:
undetectable		 1oniG-5ur2A:
10.16
1oniI-5ur2A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 7 ILE A 807
PRO A 857
PHE A 844
ALA A 802
 None
 1.08A 1oniG-5ur2A:
undetectable
1oniI-5ur2A:
undetectable		 1oniG-5ur2A:
10.16
1oniI-5ur2A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 GLU A 503
ASN A 496
TRP A 673
 None
 1.05A 1r15D-5ur2A:
undetectable		 1r15D-5ur2A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 GLU A 503
ASN A 496
TRP A 673
 None
 1.03A 1r15E-5ur2A:
undetectable		 1r15E-5ur2A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 GLU A 503
ASN A 496
TRP A 673
 None
 1.01A 1r15F-5ur2A:
undetectable		 1r15F-5ur2A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 VAL A 927
ILE A 913
SER A 909
LEU A 891
LEU A 887
 None
 1.09A 1s19A-5ur2A:
undetectable		 1s19A-5ur2A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 ILE A 255
GLY A 292
GLU A 253
ASN A 262
PRO A 258
 None
 1.17A 1sg9A-5ur2A:
5.2		 1sg9A-5ur2A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TJ2_A_ACTA2002_0
(BIFUNCTIONAL PUTA
PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 5 LYS A 196
ALA A 303
TYR A 413
ARG A 417
 P5F  A1001 (-1.3A)
P5F  A1001 (-3.4A)
None
None
 0.98A 1tj2A-5ur2A:
39.9		 1tj2A-5ur2A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 7 TYR A 602
THR A 633
THR A 711
MET A 606
 None
 1.20A 1tv8A-5ur2A:
3.9		 1tv8A-5ur2A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 765
ALA A 781
GLY A 933
SER A 779
ALA A 780
 None
 0.88A 1utdL-5ur2A:
undetectable
1utdM-5ur2A:
undetectable		 1utdL-5ur2A:
6.57
1utdM-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 765
ALA A 781
GLY A 933
SER A 779
ALA A 780
 None
 0.89A 1utdO-5ur2A:
undetectable
1utdP-5ur2A:
undetectable		 1utdO-5ur2A:
6.57
1utdP-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 11 GLY A 765
ALA A 781
GLY A 933
SER A 779
ALA A 780
 None
 0.91A 1utdP-5ur2A:
undetectable
1utdQ-5ur2A:
undetectable		 1utdP-5ur2A:
6.57
1utdQ-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 ALA A 272
VAL A 321
TRP A 305
 None
None
P5F  A1001 (-3.7A)
 0.92A 1w5uA-5ur2A:
undetectable
1w5uB-5ur2A:
undetectable		 1w5uA-5ur2A:
2.82
1w5uB-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 TRP A 305
ALA A 272
VAL A 321
 P5F  A1001 (-3.7A)
None
None
 0.84A 1w5uA-5ur2A:
undetectable
1w5uB-5ur2A:
undetectable		 1w5uA-5ur2A:
2.82
1w5uB-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_A_SPMA924_1
(FMS1 PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 11 ASN A 235
LEU A 200
PHE A 224
LEU A 220
TYR A 156
 None
 1.48A 1xpqA-5ur2A:
undetectable		 1xpqA-5ur2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_C_SPMC921_1
(FMS1 PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 11 ASN A 235
LEU A 200
PHE A 224
LEU A 220
TYR A 156
 None
 1.50A 1xpqC-5ur2A:
undetectable		 1xpqC-5ur2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 LEU A 562
ALA A 647
ASP A 569
LEU A 573
ILE A 592
 None
 1.06A 1yi4A-5ur2A:
undetectable		 1yi4A-5ur2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 11 PHE A 138
ALA A 402
GLU A 385
LEU A 128
VAL A 127
 None
 0.94A 2bxeB-5ur2A:
2.1		 2bxeB-5ur2A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 7 TYR A 602
THR A 633
THR A 711
MET A 606
 None
 1.21A 2fb2B-5ur2A:
4.7		 2fb2B-5ur2A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 ALA A 272
VAL A 321
TRP A 305
 None
None
P5F  A1001 (-3.7A)
 0.93A 2izqA-5ur2A:
undetectable
2izqB-5ur2A:
undetectable		 2izqA-5ur2A:
2.82
2izqB-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 TRP A 305
ALA A 272
VAL A 321
 P5F  A1001 (-3.7A)
None
None
 0.94A 2izqC-5ur2A:
undetectable
2izqD-5ur2A:
undetectable		 2izqC-5ur2A:
2.82
2izqD-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 8 VAL A 820
PRO A 819
PRO A 515
SER A 518
 None
 0.98A 2v32C-5ur2A:
2.7
2v32D-5ur2A:
2.1		 2v32C-5ur2A:
12.63
2v32D-5ur2A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 LEU A 959
TYR A 958
GLN A 961
 None
 0.67A 2wekA-5ur2A:
4.9		 2wekA-5ur2A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 TYR A 307
THR A 309
VAL A 319
VAL A 321
LEU A 274
 None
 1.09A 3casA-5ur2A:
8.4		 3casA-5ur2A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 4 VAL A 632
ARG A 555
ILE A 679
THR A 711
 None
 1.26A 3cl9A-5ur2A:
3.0		 3cl9A-5ur2A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 TRP A 305
ALA A 272
VAL A 321
 P5F  A1001 (-3.7A)
None
None
 0.90A 3l8lC-5ur2A:
undetectable
3l8lD-5ur2A:
undetectable		 3l8lC-5ur2A:
2.82
3l8lD-5ur2A:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 11 ALA A 654
ASN A 658
VAL A 660
GLY A 648
ILE A 689
 None
 0.97A 3lzvB-5ur2A:
undetectable		 3lzvB-5ur2A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 9 ILE A 679
GLU A 681
ARG A 568
ASP A 569
LEU A 675
 None
 1.45A 3mjrA-5ur2A:
undetectable		 3mjrA-5ur2A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 648
ALA A 652
ALA A 603
VAL A 655
ALA A 595
 None
 1.34A 4df3A-5ur2A:
5.0		 4df3A-5ur2A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 876
LEU A 869
THR A 832
ILE A 833
ARG A 783
 None
 1.14A 4hytA-5ur2A:
3.0		 4hytA-5ur2A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 GLY A 876
LEU A 869
THR A 832
ILE A 833
ARG A 783
 None
 1.14A 4hytC-5ur2A:
undetectable		 4hytC-5ur2A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 PHE A 641
PRO A 638
THR A 715
GLU A 744
PHE A 941
 None
 1.37A 4k88A-5ur2A:
undetectable		 4k88A-5ur2A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 8 SER A 907
SER A 909
HIS A  70
GLU A  66
 None
 1.10A 4ms4A-5ur2A:
2.6		 4ms4A-5ur2A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 GLY A 818
PRO A 819
GLN A 776
 None
 0.39A 4oltB-5ur2A:
1.0		 4oltB-5ur2A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 GLY A 818
PRO A 819
GLN A 776
 None
 0.28A 4qwpB-5ur2A:
0.5		 4qwpB-5ur2A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 ALA A 349
TRP A 296
VAL A 297
 None
 0.45A 4w9nC-5ur2A:
undetectable		 4w9nC-5ur2A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 4 ILE A   4
ARG A 356
TYR A 364
GLU A 333
 None
 1.10A 4zzbD-5ur2A:
2.2		 4zzbD-5ur2A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 5 ILE A   4
ARG A 356
TYR A 364
GLU A 333
 None
 1.16A 4zzcE-5ur2A:
2.2		 4zzcE-5ur2A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 6 GLU A 327
GLY A 430
ASP A 434
ARG A 429
 None
 0.83A 5cdnC-5ur2A:
3.0
5cdnD-5ur2A:
undetectable		 5cdnC-5ur2A:
20.40
5cdnD-5ur2A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		4 / 6 GLU A 327
GLY A 430
ASP A 434
ARG A 429
 None
 0.80A 5cdnT-5ur2A:
undetectable
5cdnU-5ur2A:
2.1		 5cdnT-5ur2A:
20.40
5cdnU-5ur2A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.18A 5eeyO-5ur2A:
undetectable
5eeyP-5ur2A:
undetectable		 5eeyO-5ur2A:
6.57
5eeyP-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.18A 5eezO-5ur2A:
undetectable
5eezP-5ur2A:
undetectable		 5eezO-5ur2A:
6.57
5eezP-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.18A 5ef0O-5ur2A:
undetectable
5ef0P-5ur2A:
undetectable		 5ef0O-5ur2A:
6.57
5ef0P-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.18A 5ef1O-5ur2A:
undetectable
5ef1P-5ur2A:
undetectable		 5ef1O-5ur2A:
6.57
5ef1P-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.18A 5ef2O-5ur2A:
undetectable
5ef2P-5ur2A:
undetectable		 5ef2O-5ur2A:
6.57
5ef2P-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 GLY A 700
THR A 709
HIS A 706
ILE A 636
ALA A 728
 None
 1.18A 5ef3O-5ur2A:
undetectable
5ef3P-5ur2A:
undetectable		 5ef3O-5ur2A:
6.57
5ef3P-5ur2A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 MET A  19
GLN A  22
ARG A  18
 None
 1.08A 5ewzB-5ur2A:
2.7		 5ewzB-5ur2A:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 11 VAL A 195
SER A 194
ASP A 141
THR A 139
LEU A 220
 None
 1.35A 5jh7B-5ur2A:
2.4		 5jh7B-5ur2A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 MET A  19
GLN A  22
ARG A  18
 None
 1.01A 5m35B-5ur2A:
undetectable		 5m35B-5ur2A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 MET A  19
GLN A  22
ARG A  18
 None
 1.00A 5m36A-5ur2A:
2.8		 5m36A-5ur2A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 10 PRO A 664
GLY A 700
GLU A 698
GLY A 696
ALA A 533
 None
 1.12A 5o96E-5ur2A:
3.2
5o96F-5ur2A:
undetectable		 5o96E-5ur2A:
13.20
5o96F-5ur2A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 TYR A 958
ALA A 653
TYR A 962
 None
 0.86A 5uunB-5ur2A:
undetectable		 5uunB-5ur2A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		5 / 12 PHE A 641
PRO A 638
THR A 715
GLU A 744
PHE A 941
 None
 1.43A 5xipB-5ur2A:
undetectable		 5xipB-5ur2A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 MET A  19
GLN A  22
ARG A  18
 None
 1.01A 6fn9A-5ur2A:
undetectable		 6fn9A-5ur2A:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 MET A  19
GLN A  22
ARG A  18
 None
 1.04A 6fnaB-5ur2A:
undetectable		 6fnaB-5ur2A:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ur2 BIFUNCTIONAL PROTEIN
PUTA
(Bdellovibrio
bacteriovorus) 		3 / 3 MET A  19
GLN A  22
ARG A  18
 None
 1.01A 6fnbA-5ur2A:
undetectable		 6fnbA-5ur2A:
12.82