SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5urp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 ARG A  83
SER A 128
ARG A 140
GLU A 168
 None
GOL  A 301 ( 4.2A)
None
GOL  A 301 (-3.4A)
 0.94A 2c8aA-5urpA:
28.0		 2c8aA-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 ARG A  83
SER A 128
GLN A 166
GLU A 168
 None
GOL  A 301 ( 4.2A)
GOL  A 301 (-3.5A)
GOL  A 301 (-3.4A)
 0.54A 2c8aA-5urpA:
28.0		 2c8aA-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 ARG A  83
SER A 128
PHE A 137
GLU A 168
 None
GOL  A 301 ( 4.2A)
None
GOL  A 301 (-3.4A)
 1.33A 2c8aA-5urpA:
28.0		 2c8aA-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 SER A 128
SER A 130
GLN A 166
GLU A 168
 GOL  A 301 ( 4.2A)
GOL  A 301 ( 4.8A)
GOL  A 301 (-3.5A)
GOL  A 301 (-3.4A)
 0.78A 2c8aA-5urpA:
28.0		 2c8aA-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 ARG A  83
GLY A  84
SER A 128
ARG A 140
 None
None
GOL  A 301 ( 4.2A)
None
 0.75A 2c8aB-5urpA:
27.4		 2c8aB-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 ARG A  83
GLY A  84
SER A 128
GLU A 168
 None
None
GOL  A 301 ( 4.2A)
GOL  A 301 (-3.4A)
 0.32A 2c8aB-5urpA:
27.4		 2c8aB-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 GLY A  84
SER A 128
SER A 130
GLU A 168
 None
GOL  A 301 ( 4.2A)
GOL  A 301 ( 4.8A)
GOL  A 301 (-3.4A)
 0.87A 2c8aB-5urpA:
27.4		 2c8aB-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 6 ARG A  83
SER A 128
ARG A 140
GLU A 168
 None
GOL  A 301 ( 4.2A)
None
GOL  A 301 (-3.4A)
 0.99A 2c8aC-5urpA:
27.0		 2c8aC-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		5 / 7 ARG A  83
GLY A  84
SER A 128
ARG A 140
GLU A 168
 None
None
GOL  A 301 ( 4.2A)
None
GOL  A 301 (-3.4A)
 0.89A 2c8aD-5urpA:
27.6		 2c8aD-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 7 GLY A  84
SER A 128
SER A 130
GLU A 168
 None
GOL  A 301 ( 4.2A)
GOL  A 301 ( 4.8A)
GOL  A 301 (-3.4A)
 0.87A 2c8aD-5urpA:
27.6		 2c8aD-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		4 / 6 THR A 119
GLU A 117
LYS A 194
ILE A 112
 None
 1.25A 2w98B-5urpA:
undetectable		 2w98B-5urpA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		5 / 9 LEU A 131
GLY A 155
VAL A  79
VAL A  81
LEU A 146
 None
 1.07A 4qd3A-5urpA:
undetectable		 4qd3A-5urpA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		3 / 3 TYR A 156
LYS A  16
LYS A  12
 None
 0.91A 5dbyA-5urpA:
undetectable		 5dbyA-5urpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		3 / 3 ILE A   6
MET A 169
ASP A   3
 None
 0.77A 5h2uA-5urpA:
undetectable		 5h2uA-5urpA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 5urp TOXIN 2A
(Paenibacillus
larvae) 		3 / 3 LYS A  23
TRP A  22
SER A  20
 None
 1.18A 5nwwA-5urpA:
undetectable		 5nwwA-5urpA:
23.53