SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5usd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 5 THR A 237
THR A 233
THR A 207
HIS A 299
 None
None
None
DSZ  A 401 (-4.0A)
 1.19A 1d4fB-5usdA:
2.8		 1d4fB-5usdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 5 THR A 301
THR A 300
GLU A 228
HIS A 133
 None
None
None
DSZ  A 401 (-4.2A)
 1.32A 1d4fB-5usdA:
2.8		 1d4fB-5usdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 7 LEU A 227
PHE A 226
GLY A 263
ILE A 273
 None
 1.05A 2bdmA-5usdA:
undetectable		 2bdmA-5usdA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 11 LEU A  99
ASN A 103
VAL A  76
ALA A  70
ARG A  72
 None
 1.14A 2bxgA-5usdA:
undetectable		 2bxgA-5usdA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 12 ALA A 196
ILE A 314
VAL A 257
LEU A 248
ILE A 201
 None
 1.11A 2h42B-5usdA:
undetectable		 2h42B-5usdA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		3 / 3 LYS A   5
TYR A 129
PRO A   3
 None
 1.47A 2j9cC-5usdA:
undetectable		 2j9cC-5usdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 8 SER A 206
THR A 207
LEU A 116
THR A 237
 None
 0.82A 2v0zO-5usdA:
undetectable		 2v0zO-5usdA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		3 / 3 TYR A 244
GLU A 229
THR A 114
 None
 0.94A 2y7hB-5usdA:
undetectable		 2y7hB-5usdA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 12 GLY A 194
GLY A 259
ALA A 196
THR A 313
ALA A 312
 None
 0.89A 3sugA-5usdA:
undetectable		 3sugA-5usdA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		3 / 3 TYR A 121
MET A 205
LEU A 225
 None
 0.83A 3vw1D-5usdA:
undetectable		 3vw1D-5usdA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 9 ALA A 293
TYR A 188
PHE A 226
SER A 296
GLY A 263
 None
 1.17A 4mm5A-5usdA:
undetectable		 4mm5A-5usdA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 12 ALA A 293
TYR A 188
PHE A 226
SER A 296
GLY A 263
 None
 1.08A 4mm6A-5usdA:
undetectable		 4mm6A-5usdA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 11 ALA A 293
TYR A 188
PHE A 226
SER A 296
GLY A 263
 None
 1.21A 4mm9A-5usdA:
undetectable		 4mm9A-5usdA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 11 ALA A 293
TYR A 188
PHE A 226
SER A 296
GLY A 263
 None
 0.99A 4mmaA-5usdA:
undetectable		 4mmaA-5usdA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 12 ALA A 293
TYR A 188
PHE A 226
SER A 296
GLY A 263
 None
 1.02A 4mmdB-5usdA:
undetectable		 4mmdB-5usdA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 6 SER A 322
GLY A 310
ASP A 199
ARG A 311
 None
 0.73A 5cdnC-5usdA:
undetectable
5cdnD-5usdA:
undetectable		 5cdnC-5usdA:
21.67
5cdnD-5usdA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 6 SER A 322
GLY A 310
ASP A 199
ARG A 311
 None
 0.80A 5cdnT-5usdA:
undetectable
5cdnU-5usdA:
undetectable		 5cdnT-5usdA:
21.67
5cdnU-5usdA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 12 ILE A 113
PHE A 107
SER A  16
LEU A  91
GLY A 131
 None
 1.18A 5i75A-5usdA:
undetectable		 5i75A-5usdA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 10 THR A 207
LEU A 211
GLY A 203
GLY A 202
LEU A 116
 None
 0.79A 5l0zB-5usdA:
2.0		 5l0zB-5usdA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		5 / 12 LEU A 286
PHE A 254
ILE A 289
ALA A 196
GLY A 202
 None
 1.01A 5veuH-5usdA:
undetectable		 5veuH-5usdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5usd PEPTIDASE S66
(Bacillus
anthracis) 		4 / 5 TYR A 244
ARG A 243
THR A 233
LEU A 232
 None
 1.29A 5x19J-5usdA:
undetectable		 5x19J-5usdA:
11.80