SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5usl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		3 / 3 GLU X  90
ASN X  92
TRP X 182
 None
 1.14A 1r15C-5uslX:
undetectable		 1r15C-5uslX:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		3 / 3 GLU X  90
ASN X  92
TRP X 182
 None
 1.20A 1r15D-5uslX:
undetectable		 1r15D-5uslX:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		3 / 3 GLU X  90
ASN X  92
TRP X 182
 None
 1.17A 1r15E-5uslX:
undetectable		 1r15E-5uslX:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		3 / 3 GLU X  90
ASN X  92
TRP X 182
 None
 1.18A 1r15F-5uslX:
undetectable		 1r15F-5uslX:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		5 / 12 PHE X 185
ILE X 119
ILE X  91
HIS X  95
LEU X  63
 None
 1.20A 2ft9A-5uslX:
1.9		 2ft9A-5uslX:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		4 / 7 SER X  65
HIS X  67
ARG X  44
TYR X 104
 None
 1.28A 2vmyA-5uslX:
undetectable
2vmyB-5uslX:
undetectable		 2vmyA-5uslX:
18.78
2vmyB-5uslX:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		4 / 8 TYR X 104
SER X  65
HIS X  67
ARG X  44
 None
 1.25A 2vmyA-5uslX:
undetectable
2vmyB-5uslX:
undetectable		 2vmyA-5uslX:
18.78
2vmyB-5uslX:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		5 / 12 LEU X 159
LEU X 160
LEU X  93
ILE X 134
ILE X  45
 None
 1.15A 4j24A-5uslX:
undetectable		 4j24A-5uslX:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		5 / 12 LEU X 160
PHE X 185
ILE X  52
LEU X  24
ILE X 183
 None
 1.11A 4nx6A-5uslX:
undetectable		 4nx6A-5uslX:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		5 / 12 LEU X 160
PHE X 185
ILE X  52
LEU X  24
ILE X 183
 None
 1.10A 4nx7A-5uslX:
undetectable		 4nx7A-5uslX:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5usl IMV MEMBRANE PROTEIN
(Vaccinia
virus) 		3 / 3 SER X 118
HIS X  80
TYR X 169
 None
 0.97A 5y2tA-5uslX:
undetectable		 5y2tA-5uslX:
undetectable