SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5uso PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A  59
ASP A  87
ASP A 124
 None
 0.57A 2ejtA-5usoA:
undetectable		 2ejtA-5usoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5uso PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A  35
VAL A  37
CYH A  79
VAL A  94
LEU A 104
 None
 1.38A 2hc4A-5usoA:
undetectable		 2hc4A-5usoA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5uso PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A  35
VAL A  37
CYH A  79
VAL A  94
LEU A 104
 None
 1.43A 2zlcA-5usoA:
undetectable		 2zlcA-5usoA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5uso PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 VAL A  23
ALA A  21
VAL A  89
TYR A  88
 None
 1.04A 5i8fA-5usoA:
undetectable		 5i8fA-5usoA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5uso PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A  19
LEU A   8
ALA A  21
SER A  66
 None
 0.83A 6f88A-5usoA:
undetectable		 6f88A-5usoA:
19.32