SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uti'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 5 LEU A 259
SER A 214
LEU A 218
GLY A 229
 None
None
None
GGB  A 403 (-3.3A)
 1.07A 1a4lB-5utiA:
5.3		 1a4lB-5utiA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 7 ASP A 315
GLU A 317
TRP A 296
PHE A 377
 None
PG4  A 405 (-3.8A)
PG4  A 405 (-3.8A)
None
 1.49A 1b2iA-5utiA:
undetectable		 1b2iA-5utiA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 PRO A 265
ASP A 315
TRP A 296
TYR A 381
 None
None
PG4  A 405 (-3.8A)
None
 1.40A 1hpkA-5utiA:
undetectable		 1hpkA-5utiA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 12 GLY A 200
MET A 278
LEU A 100
MET A 153
ILE A 201
 None
None
None
None
GGB  A 403 ( 4.9A)
 0.98A 1lhuA-5utiA:
undetectable		 1lhuA-5utiA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 HIS A  90
PHE A 199
LEU A 100
ILE A  66
 None
 1.23A 1sbrA-5utiA:
undetectable
1sbrB-5utiA:
undetectable		 1sbrA-5utiA:
22.16
1sbrB-5utiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 7 ASN A 350
HIS A 349
PHE A 353
ILE A 300
 None
ZN  A 401 (-3.2A)
None
None
 1.45A 1tdnA-5utiA:
undetectable		 1tdnA-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 ARG A  38
ARG A 362
ILE A  30
 None
 0.61A 1uobA-5utiA:
undetectable		 1uobA-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 MET A 260
MET A 240
VAL A 243
LEU A 244
 GGB  A 403 (-3.7A)
None
None
None
 0.77A 1x8vA-5utiA:
undetectable		 1x8vA-5utiA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 11 ARG A 362
ILE A 276
LEU A 244
PHE A 241
GLY A 270
 None
 1.39A 2bxmA-5utiA:
undetectable		 2bxmA-5utiA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 8 ARG A 274
LEU A 244
VAL A 262
GLY A 263
 None
 0.97A 2po5A-5utiA:
undetectable		 2po5A-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 MET A 176
SER A 214
ARG A 211
GLY A 204
 None
 1.46A 2y7pA-5utiA:
undetectable		 2y7pA-5utiA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 8 MET A 346
ALA A 343
GLY A 342
ILE A 335
 None
 0.91A 2zm9A-5utiA:
undetectable		 2zm9A-5utiA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 11 MET A  32
ILE A  30
LEU A 100
ILE A  66
PRO A 256
 None
 1.38A 3a50B-5utiA:
undetectable		 3a50B-5utiA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 9 GLY A 148
GLN A 192
ASP A 150
ILE A  99
GLN A 144
 None
 1.44A 3fi0L-5utiA:
undetectable		 3fi0L-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 TYR A 354
VAL A  51
THR A 285
PHE A  42
 None
 1.37A 3ltwA-5utiA:
undetectable		 3ltwA-5utiA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 9 ILE A 276
GLU A 273
GLN A 237
ARG A 378
ASP A 266
 None
 1.33A 3mjrA-5utiA:
0.9		 3mjrA-5utiA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 12 CYH A 281
ASN A 350
LEU A 357
ILE A 268
LEU A 259
 None
 1.42A 4k36B-5utiA:
4.4		 4k36B-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 ILE A  37
ASP A  65
ARG A  38
GLY A  28
 None
 1.03A 4oltA-5utiA:
undetectable		 4oltA-5utiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 ILE A  37
ASP A  65
ARG A  38
GLY A  28
 None
 1.02A 4oltB-5utiA:
undetectable		 4oltB-5utiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 12 GLY A  69
ASN A  70
HIS A  73
HIS A  90
LEU A  68
 None
 1.33A 4pooA-5utiA:
undetectable		 4pooA-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQD_A_GAIA1005_0
(THIOSULFATE
DEHYDROGENASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 4 ARG A  38
ARG A 362
GLY A  63
ARG A  60
 None
 1.44A 4wqdA-5utiA:
0.0		 4wqdA-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 THR A  71
SER A 140
ASP A 156
 None
None
GGB  A 403 (-3.1A)
 0.76A 5kvaB-5utiA:
2.7		 5kvaB-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 MET A 240
GLN A 237
ARG A 274
 None
 1.02A 5m35B-5utiA:
undetectable		 5m35B-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 MET A 240
GLN A 237
ARG A 274
 None
 0.97A 5m36A-5utiA:
undetectable		 5m36A-5utiA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 9 ASP A 156
GLN A 203
GLY A 229
ALA A 232
MET A 260
 GGB  A 403 (-3.1A)
None
GGB  A 403 (-3.3A)
GGB  A 403 ( 4.1A)
GGB  A 403 (-3.7A)
 1.33A 5v3cA-5utiA:
58.7		 5v3cA-5utiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		8 / 9 TYR A 106
ASP A 156
GLN A 203
GLY A 229
GLY A 230
ALA A 232
VAL A 233
MET A 260
 GGB  A 403 (-3.9A)
GGB  A 403 (-3.1A)
None
GGB  A 403 (-3.3A)
GGB  A 403 (-3.8A)
GGB  A 403 ( 4.1A)
None
GGB  A 403 (-3.7A)
 0.36A 5v3cA-5utiA:
58.7		 5v3cA-5utiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 9 TYR A 106
CYH A 158
GLN A 203
GLY A 229
MET A 260
 GGB  A 403 (-3.9A)
GGB  A 403 (-3.6A)
None
GGB  A 403 (-3.3A)
GGB  A 403 (-3.7A)
 1.26A 5v3cA-5utiA:
58.7		 5v3cA-5utiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 ARG A 211
PHE A 207
GLY A 204
 None
 0.80A 6fgdA-5utiA:
undetectable		 6fgdA-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 MET A 240
GLN A 237
ARG A 274
 None
 0.98A 6fn9A-5utiA:
undetectable		 6fn9A-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 MET A 240
GLN A 237
ARG A 274
 None
 1.00A 6fnaB-5utiA:
undetectable		 6fnaB-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 MET A 240
GLN A 237
ARG A 274
 None
 0.97A 6fnbA-5utiA:
undetectable		 6fnbA-5utiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 5 GLY A 229
LEU A 231
SER A 247
GLN A 202
 GGB  A 403 (-3.3A)
None
None
None
 1.27A 6ji6A-5utiA:
undetectable		 6ji6A-5utiA:
undetectable