SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5utt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5utt SORTASE
(Actinomyces
oris) 		4 / 6 TYR A 105
ILE A 169
PRO A 247
GLU A 167
 None
 1.29A 1oniA-5uttA:
undetectable
1oniC-5uttA:
undetectable		 1oniA-5uttA:
19.69
1oniC-5uttA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5utt SORTASE
(Actinomyces
oris) 		3 / 3 PRO A  84
GLY A 138
TYR A 177
 None
 0.67A 2vouA-5uttA:
undetectable		 2vouA-5uttA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5utt SORTASE
(Actinomyces
oris) 		3 / 3 PRO A  84
GLY A 138
TYR A 177
 None
 0.58A 2vouB-5uttA:
undetectable		 2vouB-5uttA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5utt SORTASE
(Actinomyces
oris) 		3 / 3 PRO A  84
GLY A 138
TYR A 177
 None
 0.59A 2vouC-5uttA:
undetectable		 2vouC-5uttA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 5utt SORTASE
(Actinomyces
oris) 		4 / 4 GLU A 185
GLY A 183
THR A 182
GLU A 164
 None
 0.95A 3e9xA-5uttA:
undetectable		 3e9xA-5uttA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5utt SORTASE
(Actinomyces
oris) 		5 / 10 VAL A 170
PHE A 179
ILE A 114
PHE A 143
ALA A 144
 None
 1.00A 3me6A-5uttA:
undetectable		 3me6A-5uttA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 5utt SORTASE
(Actinomyces
oris) 		5 / 9 VAL A 170
PHE A 179
ILE A 114
PHE A 143
ALA A 144
 None
 0.98A 3me6C-5uttA:
undetectable		 3me6C-5uttA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5utt SORTASE
(Actinomyces
oris) 		5 / 9 VAL A 170
PHE A 179
ILE A 114
PHE A 143
ALA A 144
 None
 1.10A 3me6D-5uttA:
undetectable		 3me6D-5uttA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5utt SORTASE
(Actinomyces
oris) 		5 / 12 ASN A 142
ILE A 168
VAL A 181
ILE A 114
VAL A 101
 None
 1.41A 6j21A-5uttA:
undetectable		 6j21A-5uttA:
15.84