SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5utu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 8 THR A 212
GLY A 138
GLY A 332
GLY A 355
 NAD  A 501 ( 4.1A)
SAH  A 502 ( 3.9A)
NAD  A 501 (-3.5A)
NAD  A 501 (-3.4A)
 0.76A 1d0vA-5utuA:
2.6		 1d0vA-5utuA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 404
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
 1.32A 1d4fA-5utuA:
51.6		 1d4fA-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.33A 1d4fA-5utuA:
51.6		 1d4fA-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 5 THR A  58
GLU A 211
THR A 212
HIS A 410
 SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 ( 3.5A)
 0.72A 1d4fA-5utuA:
51.6		 1d4fA-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 404
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
 1.39A 1d4fB-5utuA:
36.1		 1d4fB-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
GLU A  57
ASP A 137
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.35A 1d4fB-5utuA:
36.1		 1d4fB-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 THR A  55
THR A  58
GLU A 211
THR A 212
HIS A 410
 SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 ( 3.5A)
 0.74A 1d4fB-5utuA:
36.1		 1d4fB-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
LYS A 241
ASP A 245
LEU A 401
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.33A 1d4fC-5utuA:
38.1		 1d4fC-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 5 THR A  58
GLU A 211
THR A 212
LEU A 404
 SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 ( 4.7A)
 0.66A 1d4fC-5utuA:
51.6		 1d4fC-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.40A 1d4fD-5utuA:
51.5		 1d4fD-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 5 THR A  58
GLU A 211
THR A 212
HIS A 410
 SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 ( 3.5A)
 0.78A 1d4fD-5utuA:
51.5		 1d4fD-5utuA:
48.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 LEU A 255
VAL A 273
ALA A 330
ILE A 328
ILE A 326
 None
 1.01A 1epbA-5utuA:
undetectable		 1epbA-5utuA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 LEU A 255
VAL A 273
ALA A 330
ILE A 328
ILE A 326
 None
 0.95A 1epbB-5utuA:
undetectable		 1epbB-5utuA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 8 THR A 212
GLY A 138
GLY A 332
GLY A 355
 NAD  A 501 ( 4.1A)
SAH  A 502 ( 3.9A)
NAD  A 501 (-3.5A)
NAD  A 501 (-3.4A)
 0.77A 1jhaA-5utuA:
2.4		 1jhaA-5utuA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 ALA A  87
VAL A  91
ALA A  88
HIS A  85
 None
 1.10A 1q23A-5utuA:
undetectable		 1q23A-5utuA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 ALA A  87
VAL A  91
ALA A  88
HIS A  85
 None
 1.19A 1q23F-5utuA:
undetectable		 1q23F-5utuA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 ALA A  87
VAL A  91
ALA A  88
HIS A  85
 None
 1.11A 1q23K-5utuA:
undetectable		 1q23K-5utuA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 8 LEU A 187
GLU A 190
GLU A 152
ILE A 144
 None
 0.88A 1qvtA-5utuA:
undetectable		 1qvtA-5utuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 10 VAL A 279
LEU A 401
GLY A 355
HIS A 410
ILE A 328
 NAD  A 501 (-3.6A)
NAD  A 501 (-4.1A)
NAD  A 501 (-3.4A)
SAH  A 502 ( 3.5A)
None
 1.14A 1sq5D-5utuA:
undetectable		 1sq5D-5utuA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.31A 1v8bA-5utuA:
56.1		 1v8bA-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.37A 1v8bA-5utuA:
56.1		 1v8bA-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.40A 1v8bB-5utuA:
55.9		 1v8bB-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.36A 1v8bB-5utuA:
55.9		 1v8bB-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.46A 1v8bC-5utuA:
56.1		 1v8bC-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.21A 1v8bC-5utuA:
56.1		 1v8bC-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.50A 1v8bC-5utuA:
56.1		 1v8bC-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.40A 1v8bD-5utuA:
55.9		 1v8bD-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.40A 1v8bD-5utuA:
55.9		 1v8bD-5utuA:
52.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
ASP A 245
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.90A 1xwfA-5utuA:
48.5		 1xwfA-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
THR A  55
GLU A  57
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.98A 1xwfA-5utuA:
48.5		 1xwfA-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
ASP A 245
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.93A 1xwfB-5utuA:
48.5		 1xwfB-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
THR A  55
GLU A  57
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 1.01A 1xwfB-5utuA:
48.5		 1xwfB-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 GLU A  57
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 SAH  A 502 (-3.7A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.94A 1xwfC-5utuA:
48.3		 1xwfC-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
HIS A  53
GLU A  57
ASP A 137
ASP A 245
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.95A 1xwfC-5utuA:
48.3		 1xwfC-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
ASP A 245
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.80A 1xwfC-5utuA:
48.3		 1xwfC-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 THR A  55
GLU A  57
ASP A 245
LEU A 401
GLY A 409
MET A 415
PHE A 419
 SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.94A 1xwfC-5utuA:
48.3		 1xwfC-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 GLU A  57
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 SAH  A 502 (-3.7A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.96A 1xwfD-5utuA:
48.3		 1xwfD-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
HIS A  53
GLU A  57
ASP A 137
ASP A 245
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.98A 1xwfD-5utuA:
48.3		 1xwfD-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
HIS A  53
THR A  55
GLU A  57
ASP A 137
ASP A 245
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.82A 1xwfD-5utuA:
48.3		 1xwfD-5utuA:
48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 THR A  55
GLU A  57
ASP A 245
LEU A 401
GLY A 409
MET A 415
PHE A 419
 SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.95A 1xwfD-5utuA:
48.3		 1xwfD-5utuA:
48.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 LEU A 254
ALA A 330
ILE A 337
VAL A 402
ILE A 354
 None
None
None
None
NAD  A 501 (-4.3A)
 0.91A 2hs2A-5utuA:
undetectable		 2hs2A-5utuA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 6 LEU A  52
SER A 238
ASP A 454
GLU A 211
 None
None
None
SAH  A 502 (-3.8A)
 0.99A 2vn1B-5utuA:
undetectable		 2vn1B-5utuA:
17.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.49A 2zj0A-5utuA:
53.5		 2zj0A-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.52A 2zj0A-5utuA:
53.5		 2zj0A-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.31A 2zj0B-5utuA:
53.7		 2zj0B-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.65A 2zj0B-5utuA:
53.7		 2zj0B-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
ASP A 245
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.5A)
 1.27A 2zj0B-5utuA:
53.7		 2zj0B-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 THR A  58
ASP A 137
ASP A 245
LEU A 404
HIS A 410
 SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.39A 2zj0B-5utuA:
53.7		 2zj0B-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.33A 2zj0C-5utuA:
53.6		 2zj0C-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.60A 2zj0C-5utuA:
53.6		 2zj0C-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 2zj0D-5utuA:
53.7		 2zj0D-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.56A 2zj0D-5utuA:
53.7		 2zj0D-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.26A 2zj0D-5utuA:
53.7		 2zj0D-5utuA:
49.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
ASP A 245
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.5A)
 1.27A 2zj0D-5utuA:
53.7		 2zj0D-5utuA:
49.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 6 LEU A 254
GLY A 249
LEU A 287
SER A 288
 None
 0.77A 3aiaA-5utuA:
1.4		 3aiaA-5utuA:
19.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
ASP A 245
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.5A)
 1.25A 3ce6A-5utuA:
53.7		 3ce6A-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.55A 3ce6A-5utuA:
53.7		 3ce6A-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
 1.12A 3ce6B-5utuA:
53.7		 3ce6B-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.66A 3ce6B-5utuA:
53.7		 3ce6B-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
ASP A 245
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.5A)
 1.26A 3ce6B-5utuA:
53.7		 3ce6B-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
ASP A 245
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.5A)
 1.25A 3ce6C-5utuA:
53.8		 3ce6C-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.54A 3ce6C-5utuA:
53.8		 3ce6C-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.60A 3ce6D-5utuA:
53.7		 3ce6D-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.42A 3ce6D-5utuA:
53.7		 3ce6D-5utuA:
49.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		8 / 12 LEU A  52
HIS A  53
ASP A 137
GLU A 211
ASN A 246
LEU A 401
LEU A 404
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 (-3.5A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 (-4.8A)
 0.86A 3g1uA-5utuA:
50.6		 3g1uA-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.64A 3g1uA-5utuA:
50.6		 3g1uA-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.51A 3g1uB-5utuA:
50.5		 3g1uB-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
 1.40A 3g1uC-5utuA:
51.3		 3g1uC-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 LEU A  52
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
 None
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
 0.97A 3g1uC-5utuA:
51.3		 3g1uC-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.49A 3g1uC-5utuA:
51.3		 3g1uC-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.51A 3g1uD-5utuA:
51.2		 3g1uD-5utuA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 LEU A  52
ASP A 137
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 None
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.25A 3glqA-5utuA:
55.2		 3glqA-5utuA:
50.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.39A 3glqA-5utuA:
55.2		 3glqA-5utuA:
50.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 LEU A  52
ASP A 137
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 None
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.23A 3glqB-5utuA:
45.4		 3glqB-5utuA:
50.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.41A 3glqB-5utuA:
45.4		 3glqB-5utuA:
50.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 11 GLY A 275
GLY A 277
GLU A 298
ILE A 299
ASP A 300
 NAD  A 501 (-3.6A)
NAD  A 501 (-3.3A)
NAD  A 501 (-2.7A)
NAD  A 501 (-4.1A)
None
 0.61A 3grvA-5utuA:
4.3		 3grvA-5utuA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 GLY A 275
GLY A 277
GLU A 298
ILE A 299
ASP A 300
 NAD  A 501 (-3.6A)
NAD  A 501 (-3.3A)
NAD  A 501 (-2.7A)
NAD  A 501 (-4.1A)
None
 0.60A 3gryA-5utuA:
4.3		 3gryA-5utuA:
21.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 10 LEU A  52
HIS A  53
THR A  55
THR A  58
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.17A 3h9uA-5utuA:
52.9		 3h9uA-5utuA:
51.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H9U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 10 HIS A  53
THR A  55
THR A  58
ASN A 403
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.23A 3h9uB-5utuA:
52.9		 3h9uB-5utuA:
51.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 10 LEU A  52
HIS A  53
THR A  55
THR A  58
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.19A 3h9uC-5utuA:
53.1		 3h9uC-5utuA:
51.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 10 LEU A  52
HIS A  53
THR A  55
THR A  58
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.19A 3h9uD-5utuA:
53.2		 3h9uD-5utuA:
51.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 LEU A  52
ASP A 137
LYS A 241
ASP A 245
LEU A 404
 None
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
 1.00A 3n58A-5utuA:
43.0		 3n58A-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.37A 3n58A-5utuA:
43.0		 3n58A-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.49A 3n58C-5utuA:
55.0		 3n58C-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.48A 3n58C-5utuA:
55.0		 3n58C-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 3n58D-5utuA:
54.9		 3n58D-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.48A 3n58D-5utuA:
54.9		 3n58D-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
LEU A 404
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.45A 3n58D-5utuA:
54.9		 3n58D-5utuA:
52.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		8 / 12 HIS A  53
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.41A 3ondA-5utuA:
55.3		 3ondA-5utuA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.37A 3ondA-5utuA:
55.3		 3ondA-5utuA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.47A 3ondA-5utuA:
55.3		 3ondA-5utuA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.35A 3ondB-5utuA:
54.8		 3ondB-5utuA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.36A 3ondB-5utuA:
54.8		 3ondB-5utuA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.46A 3ondB-5utuA:
54.8		 3ondB-5utuA:
55.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 7 THR A 212
ASN A 246
ASP A 137
HIS A  53
 NAD  A 501 ( 4.1A)
NAD  A 501 (-3.5A)
SAH  A 502 (-3.4A)
SAH  A 502 (-4.0A)
 1.00A 3t01A-5utuA:
undetectable		 3t01A-5utuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 7 ASP A 140
GLY A  50
THR A  49
ILE A 134
 None
 0.87A 4acaC-5utuA:
2.9		 4acaC-5utuA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 6 MET A 201
GLY A 200
TRP A 198
GLU A 190
 None
 1.25A 4bqfA-5utuA:
4.0		 4bqfA-5utuA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 6 SER A 238
ASP A 237
SER A 242
GLU A 211
 None
None
None
SAH  A 502 (-3.8A)
 1.20A 4eysA-5utuA:
2.4		 4eysA-5utuA:
24.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.44A 4lvcA-5utuA:
54.6		 4lvcA-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.21A 4lvcA-5utuA:
54.6		 4lvcA-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.17A 4lvcB-5utuA:
54.7		 4lvcB-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 5 THR A  58
THR A 212
LEU A 401
LEU A 404
 SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
 0.45A 4lvcB-5utuA:
54.7		 4lvcB-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.44A 4lvcC-5utuA:
54.6		 4lvcC-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.19A 4lvcC-5utuA:
54.6		 4lvcC-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.24A 4pfjA-5utuA:
53.8		 4pfjA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 7 GLU A  57
THR A  58
THR A 212
LEU A 401
ASN A 403
SER A 418
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.5A)
 0.63A 4pfjA-5utuA:
53.8		 4pfjA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.63A 4pfjB-5utuA:
53.0		 4pfjB-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 6 GLU A  57
THR A  58
GLN A  83
THR A 212
ASN A 403
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
None
NAD  A 501 ( 4.1A)
NAD  A 501 (-2.9A)
 0.56A 4pfjB-5utuA:
53.0		 4pfjB-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
ASN A 403
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
NAD  A 501 (-2.9A)
 1.50A 4pgfA-5utuA:
53.5		 4pgfA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
ASN A 403
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.43A 4pgfA-5utuA:
53.5		 4pgfA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 6 THR A  55
GLU A  57
THR A  58
THR A 212
LEU A 404
 SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
SAH  A 502 ( 4.7A)
 0.40A 4pgfA-5utuA:
53.5		 4pgfA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
GLU A  57
ASP A 137
GLU A 211
LYS A 241
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.66A 4pgfB-5utuA:
52.5		 4pgfB-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
GLU A  57
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.44A 4pgfB-5utuA:
52.5		 4pgfB-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 5 THR A  55
THR A  58
THR A 212
ASN A 403
 SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-2.9A)
 0.41A 4pgfB-5utuA:
52.5		 4pgfB-5utuA:
47.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 SER A  81
ASP A 137
GLY A 138
ASP A 140
LEU A 143
 None
SAH  A 502 (-3.4A)
SAH  A 502 ( 3.9A)
None
None
 1.40A 4pghB-5utuA:
2.8		 4pghB-5utuA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 GLU A  57
VAL A  62
LEU A  54
THR A  55
VAL A  98
 SAH  A 502 (-3.7A)
None
None
SAH  A 502 (-2.7A)
None
 1.20A 4xiwB-5utuA:
undetectable
4xiwE-5utuA:
undetectable		 4xiwB-5utuA:
18.49
4xiwE-5utuA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 11 GLU A  57
VAL A  62
LEU A  54
THR A  55
ALA A  86
 SAH  A 502 (-3.7A)
None
None
SAH  A 502 (-2.7A)
None
 1.33A 4yhaD-5utuA:
undetectable		 4yhaD-5utuA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 7 ILE A 354
LEU A 254
GLY A 282
LYS A 281
 NAD  A 501 (-4.3A)
None
None
None
 1.00A 4z69A-5utuA:
undetectable		 4z69A-5utuA:
21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.36A 5axaA-5utuA:
53.7		 5axaA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.22A 5axaA-5utuA:
53.7		 5axaA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
THR A 212
HIS A 356
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 ( 4.4A)
NAD  A 501 (-4.1A)
 0.61A 5axaA-5utuA:
53.7		 5axaA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.48A 5axaC-5utuA:
53.5		 5axaC-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.23A 5axaC-5utuA:
53.5		 5axaC-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
THR A 212
HIS A 356
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 ( 4.4A)
NAD  A 501 (-4.1A)
 0.62A 5axaC-5utuA:
53.5		 5axaC-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.38A 5axdA-5utuA:
53.7		 5axdA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
GLU A  57
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
 0.35A 5axdA-5utuA:
53.7		 5axdA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.45A 5axdA-5utuA:
53.7		 5axdA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 THR A  58
HIS A 356
LEU A 401
 SAH  A 502 (-4.2A)
NAD  A 501 ( 4.4A)
NAD  A 501 (-4.1A)
 0.26A 5axdA-5utuA:
53.7		 5axdA-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.39A 5axdC-5utuA:
53.6		 5axdC-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
GLU A  57
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
 0.35A 5axdC-5utuA:
53.6		 5axdC-5utuA:
48.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.46A 5axdC-5utuA:
53.6		 5axdC-5utuA:
48.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 GLY A 139
TYR A 184
LEU A 187
ILE A 161
THR A 142
 None
 1.14A 5eskA-5utuA:
undetectable		 5eskA-5utuA:
21.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5hm8A-5utuA:
62.9		 5hm8A-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.14A 5hm8A-5utuA:
62.9		 5hm8A-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8A-5utuA:
62.9		 5hm8A-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.48A 5hm8B-5utuA:
62.7		 5hm8B-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.13A 5hm8B-5utuA:
62.7		 5hm8B-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8B-5utuA:
62.7		 5hm8B-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5hm8C-5utuA:
62.4		 5hm8C-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.14A 5hm8C-5utuA:
62.4		 5hm8C-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8C-5utuA:
62.4		 5hm8C-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5hm8D-5utuA:
62.7		 5hm8D-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.13A 5hm8D-5utuA:
62.7		 5hm8D-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8D-5utuA:
62.7		 5hm8D-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5hm8E-5utuA:
62.6		 5hm8E-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.14A 5hm8E-5utuA:
62.6		 5hm8E-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8E-5utuA:
62.6		 5hm8E-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5hm8F-5utuA:
62.7		 5hm8F-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.12A 5hm8F-5utuA:
62.7		 5hm8F-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8F-5utuA:
62.7		 5hm8F-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5hm8G-5utuA:
62.9		 5hm8G-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.14A 5hm8G-5utuA:
62.9		 5hm8G-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.64A 5hm8G-5utuA:
49.9		 5hm8G-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.48A 5hm8H-5utuA:
62.3		 5hm8H-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.13A 5hm8H-5utuA:
62.3		 5hm8H-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 5 GLU A  57
THR A  58
GLU A 211
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5hm8H-5utuA:
62.3		 5hm8H-5utuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.32A 5m5kA-5utuA:
54.7		 5m5kA-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.21A 5m5kA-5utuA:
54.7		 5m5kA-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.36A 5m5kB-5utuA:
54.6		 5m5kB-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.22A 5m5kB-5utuA:
54.6		 5m5kB-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.45A 5m5kC-5utuA:
54.5		 5m5kC-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.20A 5m5kC-5utuA:
54.5		 5m5kC-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5m66A-5utuA:
54.4		 5m66A-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.43A 5m66A-5utuA:
54.4		 5m66A-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.33A 5m66A-5utuA:
54.4		 5m66A-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.49A 5m66B-5utuA:
54.2		 5m66B-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.23A 5m66B-5utuA:
54.2		 5m66B-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
THR A  55
ASP A 137
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.34A 5m66C-5utuA:
54.7		 5m66C-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.45A 5m66C-5utuA:
54.7		 5m66C-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 5m66D-5utuA:
54.1		 5m66D-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.25A 5m66D-5utuA:
54.1		 5m66D-5utuA:
51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 THR A  58
THR A 212
LEU A 401
 SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.50A 5m66D-5utuA:
54.1		 5m66D-5utuA:
51.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 VAL A 273
VAL A 296
TYR A 312
GLN A 313
 None
None
None
SO4  A 507 (-4.6A)
 1.25A 5qggA-5utuA:
undetectable		 5qggA-5utuA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 VAL A 273
VAL A 296
TYR A 312
GLN A 313
 None
None
None
SO4  A 507 (-4.6A)
 1.28A 5qgoA-5utuA:
undetectable		 5qgoA-5utuA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 VAL A 273
VAL A 296
TYR A 312
GLN A 313
 None
None
None
SO4  A 507 (-4.6A)
 1.26A 5qgpA-5utuA:
undetectable		 5qgpA-5utuA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 VAL A 273
VAL A 296
TYR A 312
GLN A 313
 None
None
None
SO4  A 507 (-4.6A)
 1.24A 5qgqA-5utuA:
undetectable		 5qgqA-5utuA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 VAL A 273
VAL A 296
TYR A 312
GLN A 313
 None
None
None
SO4  A 507 (-4.6A)
 1.25A 5qhbA-5utuA:
undetectable		 5qhbA-5utuA:
16.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.45A 5v96A-5utuA:
55.9		 5v96A-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.22A 5v96A-5utuA:
55.9		 5v96A-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 GLU A  57
THR A  58
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.46A 5v96A-5utuA:
55.9		 5v96A-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.36A 5v96B-5utuA:
56.2		 5v96B-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.22A 5v96B-5utuA:
56.2		 5v96B-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 GLU A  57
THR A  58
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.45A 5v96B-5utuA:
56.2		 5v96B-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.46A 5v96C-5utuA:
56.0		 5v96C-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.22A 5v96C-5utuA:
56.0		 5v96C-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 GLU A  57
THR A  58
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.48A 5v96C-5utuA:
56.0		 5v96C-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.44A 5v96D-5utuA:
56.1		 5v96D-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.22A 5v96D-5utuA:
56.1		 5v96D-5utuA:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 4 GLU A  57
THR A  58
THR A 212
LEU A 401
 SAH  A 502 (-3.7A)
SAH  A 502 (-4.2A)
NAD  A 501 ( 4.1A)
NAD  A 501 (-4.1A)
 0.49A 5v96D-5utuA:
56.1		 5v96D-5utuA:
54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 ASP A 136
PHE A 357
ARG A 218
 None
SAH  A 502 (-4.8A)
None
 1.16A 5yw0A-5utuA:
undetectable		 5yw0A-5utuA:
21.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 LEU A  52
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 None
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.18A 6aphA-5utuA:
53.0		 6aphA-5utuA:
45.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.43A 6aphA-5utuA:
53.0		 6aphA-5utuA:
45.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 ILE A 375
ASN A 348
CYH A 262
 None
 0.45A 6bp4A-5utuA:
undetectable		 6bp4A-5utuA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 HIS A  53
THR A  55
THR A  58
ASP A 245
ASN A 403
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-2.8A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.32A 6exiA-5utuA:
53.7		 6exiA-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 10 GLY A 275
GLY A 277
GLU A 298
ASP A 300
CYH A 303
THR A 331
ASN A 333
 NAD  A 501 (-3.6A)
NAD  A 501 (-3.3A)
NAD  A 501 (-2.7A)
None
NAD  A 501 (-3.5A)
NAD  A 501 (-4.1A)
NAD  A 501 (-3.7A)
 0.31A 6exiA-5utuA:
53.7		 6exiA-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 LEU A 472
GLN A 476
LYS A 489
 None
 0.22A 6exiB-5utuA:
52.7		 6exiB-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 HIS A  53
THR A  55
THR A  58
LYS A 241
ASP A 245
ASN A 403
LEU A 404
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.73A 6exiB-5utuA:
52.7		 6exiB-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		3 / 3 LEU A 472
GLN A 476
LYS A 489
 None
 0.26A 6exiA-5utuA:
53.7		 6exiA-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 10 GLY A 275
GLY A 277
GLU A 298
ASP A 300
CYH A 303
THR A 331
ASN A 333
 NAD  A 501 (-3.6A)
NAD  A 501 (-3.3A)
NAD  A 501 (-2.7A)
None
NAD  A 501 (-3.5A)
NAD  A 501 (-4.1A)
NAD  A 501 (-3.7A)
 0.30A 6exiB-5utuA:
52.7		 6exiB-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		9 / 12 LEU A  52
HIS A  53
THR A  55
THR A  58
ASP A 245
ASN A 403
LEU A 404
HIS A 410
MET A 415
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-2.8A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
 0.32A 6exiC-5utuA:
53.6		 6exiC-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 LEU A  52
THR A  58
ASP A 245
ASN A 246
MET A 415
 None
SAH  A 502 (-4.2A)
SAH  A 502 (-2.8A)
NAD  A 501 (-3.5A)
SAH  A 502 (-3.6A)
 0.87A 6exiC-5utuA:
53.6		 6exiC-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 GLY A 275
GLY A 277
GLU A 298
ASP A 300
CYH A 303
THR A 331
ASN A 333
 NAD  A 501 (-3.6A)
NAD  A 501 (-3.3A)
NAD  A 501 (-2.7A)
None
NAD  A 501 (-3.5A)
NAD  A 501 (-4.1A)
NAD  A 501 (-3.7A)
 0.31A 6exiC-5utuA:
53.6
6exiD-5utuA:
52.9		 6exiC-5utuA:
9.38
6exiD-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		10 / 12 HIS A  53
THR A  55
THR A  58
ASP A 245
ASN A 403
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-2.8A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.40A 6exiD-5utuA:
52.9		 6exiD-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 GLY A 275
GLY A 277
GLU A 298
ASP A 300
CYH A 303
THR A 331
ASN A 333
 NAD  A 501 (-3.6A)
NAD  A 501 (-3.3A)
NAD  A 501 (-2.7A)
None
NAD  A 501 (-3.5A)
NAD  A 501 (-4.1A)
NAD  A 501 (-3.7A)
 0.32A 6exiC-5utuA:
53.6
6exiD-5utuA:
52.9		 6exiC-5utuA:
9.38
6exiD-5utuA:
9.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_A_ADNA502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.10A 6f3mA-5utuA:
49.3		 6f3mA-5utuA:
42.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_A_ADNA502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.39A 6f3mA-5utuA:
49.3		 6f3mA-5utuA:
42.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_B_ADNB502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 6f3mB-5utuA:
49.3		 6f3mB-5utuA:
42.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_B_ADNB502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.27A 6f3mB-5utuA:
49.3		 6f3mB-5utuA:
42.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_C_ADNC502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
HIS A 410
 SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
 1.12A 6f3mC-5utuA:
49.3		 6f3mC-5utuA:
42.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_C_ADNC502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.39A 6f3mC-5utuA:
49.3		 6f3mC-5utuA:
42.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_D_ADND502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 6f3mD-5utuA:
49.3		 6f3mD-5utuA:
42.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3M_D_ADND502_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		11 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.26A 6f3mD-5utuA:
49.3		 6f3mD-5utuA:
42.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_A_ADNA505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.48A 6f3nA-5utuA:
49.4		 6f3nA-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_A_ADNA505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.41A 6f3nA-5utuA:
49.4		 6f3nA-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_B_ADNB505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		8 / 12 HIS A  53
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.43A 6f3nB-5utuA:
49.5		 6f3nB-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_B_ADNB505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
THR A 212
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.35A 6f3nB-5utuA:
49.5		 6f3nB-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_B_ADNB505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 12 HIS A  53
THR A  58
ASP A 137
THR A 212
ASP A 245
 SAH  A 502 (-4.0A)
SAH  A 502 (-4.2A)
SAH  A 502 (-3.4A)
NAD  A 501 ( 4.1A)
SAH  A 502 (-2.8A)
 1.43A 6f3nB-5utuA:
49.5		 6f3nB-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_C_ADNC505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.49A 6f3nC-5utuA:
49.4		 6f3nC-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_C_ADNC505_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.33A 6f3nC-5utuA:
49.4		 6f3nC-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_D_ADND506_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 6f3nD-5utuA:
49.4		 6f3nD-5utuA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F3N_D_ADND506_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.42A 6f3nD-5utuA:
49.4		 6f3nD-5utuA:
42.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 6 LEU A 429
ALA A 425
LEU A 230
THR A 142
 None
 0.91A 6f88B-5utuA:
undetectable		 6f88B-5utuA:
9.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_A_ADNA501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.48A 6gbnA-5utuA:
52.8		 6gbnA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_A_ADNA501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.21A 6gbnA-5utuA:
52.8		 6gbnA-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_B_ADNB501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		6 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
 1.27A 6gbnB-5utuA:
52.5		 6gbnB-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_B_ADNB501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.26A 6gbnB-5utuA:
52.5		 6gbnB-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_C_ADNC501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.50A 6gbnC-5utuA:
52.9		 6gbnC-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_C_ADNC501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
LEU A 404
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.27A 6gbnC-5utuA:
52.9		 6gbnC-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_D_ADND501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		7 / 12 HIS A  53
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 401
HIS A 410
 SAH  A 502 (-4.0A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-4.1A)
SAH  A 502 ( 3.5A)
 1.47A 6gbnD-5utuA:
52.4		 6gbnD-5utuA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GBN_D_ADND501_1
(-)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		12 / 12 LEU A  52
HIS A  53
THR A  55
ASP A 137
GLU A 211
LYS A 241
ASP A 245
LEU A 404
GLY A 409
HIS A 410
MET A 415
PHE A 419
 None
SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-3.4A)
SAH  A 502 (-3.8A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.23A 6gbnD-5utuA:
52.4		 6gbnD-5utuA:
47.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		4 / 5 ASN A 353
GLY A 215
HIS A 356
ASP A 359
 None
None
NAD  A 501 ( 4.4A)
None
 0.97A 6gh9A-5utuA:
undetectable		 6gh9A-5utuA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 5utu ADENOSYLHOMOCYSTEINA
SE
(Cryptosporidium
parvum) 		5 / 11 THR A 212
ASN A 236
VAL A 135
THR A  58
PHE A 419
 NAD  A 501 ( 4.1A)
None
None
SAH  A 502 (-4.2A)
SAH  A 502 (-4.8A)
 1.36A 6hcoA-5utuA:
undetectable
6hcoB-5utuA:
undetectable		 6hcoA-5utuA:
21.80
6hcoB-5utuA:
21.80