SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_B_CCSB47_0 (GLUTATHIONE S-TRANSFERASE)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	4 / 7	THR A 149 LEU A 232 GLY A 234 TYR A 231	None	0.92A	1gtiB-5uu6A: undetectable	1gtiB-5uu6A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_E_CCSE47_0 (GLUTATHIONE S-TRANSFERASE)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	4 / 7	THR A 149 LEU A 232 GLY A 234 TYR A 231	None	0.92A	1gtiE-5uu6A: undetectable	1gtiE-5uu6A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA501_0 (FERROCHELATASE)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	5 / 11	LEU A 77 LEU A 157 LEU A 124 ARG A 50 ILE A 48	None	1.29A	2qd3A-5uu6A: undetectable	2qd3A-5uu6A: 19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VH3_B_DAHB2_1 (RANASMURFIN)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	4 / 8	ALA A 68 GLY A 126 SER A 72 ALA A 73	None	0.89A	2vh3B-5uu6A: undetectable	2vh3B-5uu6A: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_A_SAMA201_0 (YAEB-LIKE PROTEIN RPA0152)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	5 / 12	LEU A 31 LEU A 157 ARG A 50 GLY A 126 LEU A 27	None	1.33A	3okxA-5uu6A: undetectable	3okxA-5uu6A: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_A_AERA601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	5 / 12	LEU A 77 ALA A 119 ILE A 48 GLY A 34 ALA A 33	None	1.04A	4nkvA-5uu6A: undetectable	4nkvA-5uu6A: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_C_AERC601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	5 / 12	LEU A 77 ALA A 119 ILE A 48 GLY A 34 ALA A 33	None	1.02A	4nkvC-5uu6A: undetectable	4nkvC-5uu6A: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_D_AERD601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	5uu6	NADPH-FLAVIN OXIDOREDUCTASE (Vibrio parahaemolyticus)	5 / 12	LEU A 77 ALA A 119 ILE A 48 GLY A 34 ALA A 33	None	1.02A	4nkvD-5uu6A: undetectable	4nkvD-5uu6A: 19.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_B_CCSB47_0","GLUTATHIONE S-TRANSFERASE","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",4,"THR A 149;LEU A 232;GLY A 234;TYR A 231","None","0.92A","1gtiB-5uu6A:undetectable","1gtiB-5uu6A:21.07"],["1GTI_E_CCSE47_0","GLUTATHIONE S-TRANSFERASE","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",4,"THR A 149;LEU A 232;GLY A 234;TYR A 231","None","0.92A","1gtiE-5uu6A:undetectable","1gtiE-5uu6A:21.07"],["2QD3_A_CHDA501_0","FERROCHELATASE","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",5,"LEU A  77;LEU A 157;LEU A 124;ARG A  50;ILE A  48","None","1.29A","2qd3A-5uu6A:undetectable","2qd3A-5uu6A:19.61"],["2VH3_B_DAHB2_1","RANASMURFIN","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",4,"ALA A  68;GLY A 126;SER A  72;ALA A  73","None","0.89A","2vh3B-5uu6A:undetectable","2vh3B-5uu6A:20.34"],["3OKX_A_SAMA201_0","YAEB-LIKE PROTEIN RPA0152","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",5,"LEU A  31;LEU A 157;ARG A  50;GLY A 126;LEU A  27","None","1.33A","3okxA-5uu6A:undetectable","3okxA-5uu6A:21.81"],["4NKV_A_AERA601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",5,"LEU A  77;ALA A 119;ILE A  48;GLY A  34;ALA A  33","None","1.04A","4nkvA-5uu6A:undetectable","4nkvA-5uu6A:19.83"],["4NKV_C_AERC601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",5,"LEU A  77;ALA A 119;ILE A  48;GLY A  34;ALA A  33","None","1.02A","4nkvC-5uu6A:undetectable","4nkvC-5uu6A:19.83"],["4NKV_D_AERD601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","5uu6","NADPH-FLAVIN OXIDOREDUCTASE","Vibrio parahaemolyticus",5,"LEU A  77;ALA A 119;ILE A  48;GLY A  34;ALA A  33","None","1.02A","4nkvD-5uu6A:undetectable","4nkvD-5uu6A:19.83"]]