SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		3 / 3 ARG A 177
THR A 184
VAL A 131
 None
 0.89A 1hxbA-5uujA:
undetectable		 1hxbA-5uujA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		3 / 3 ALA A 299
VAL A 297
TRP A   5
 None
 1.02A 1tkqA-5uujA:
undetectable		 1tkqA-5uujA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		3 / 3 TYR A  90
ARG A  51
GLN A  16
 None
 0.77A 1tw4A-5uujA:
undetectable		 1tw4A-5uujA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		3 / 3 SER A 307
THR A  78
GLN A  37
 None
 0.80A 2fk8A-5uujA:
undetectable		 2fk8A-5uujA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		3 / 3 ARG A 177
THR A 184
VAL A 131
 None
 0.94A 2qakA-5uujA:
undetectable		 2qakA-5uujA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		4 / 5 PRO A  84
ILE A 181
TRP A  73
PHE A 190
 None
 1.08A 3topB-5uujA:
undetectable		 3topB-5uujA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		5 / 12 PHE A   9
GLY A 321
PRO A 290
ALA A 218
GLY A 216
 None
 1.30A 3v3oB-5uujA:
undetectable		 3v3oB-5uujA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		4 / 6 GLY A 255
VAL A 253
TRP A   5
ASP A 252
 None
 1.14A 3vqrA-5uujA:
undetectable		 3vqrA-5uujA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		3 / 3 LYS A 102
PRO A 103
SER A 104
 None
 0.27A 4k50I-5uujA:
undetectable		 4k50I-5uujA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5uuj ALKZ
(Streptomyces
sahachiroi) 		4 / 6 VAL A 253
ALA A   3
GLN A   7
VAL A   8
 None
 1.03A 5i8fA-5uujA:
undetectable		 5i8fA-5uujA:
18.13