SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMB_A_PXBA692_1 (LACTOTRANSFERRIN)	5uus	POSSIBLE SORTASE-LIKE PROTEIN (Corynebacterium diphtheriae)	3 / 3	PRO A 219 GLU A 199 TYR A 198	None	0.80A	2zmbA-5uusA: undetectable	2zmbA-5uusA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K9F_F_LFXF0_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B)	5uus	POSSIBLE SORTASE-LIKE PROTEIN (Corynebacterium diphtheriae)	4 / 5	SER A 161 ARG A 126 GLY A 232 GLU A 231	None	1.28A	3k9fA-5uusA: undetectable 3k9fB-5uusA: undetectable 3k9fC-5uusA: undetectable	3k9fA-5uusA: 20.16 3k9fB-5uusA: 20.16 3k9fC-5uusA: 23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROD_D_NCAD302_0 (NICOTINAMIDE N-METHYLTRANSFERASE)	5uus	POSSIBLE SORTASE-LIKE PROTEIN (Corynebacterium diphtheriae)	4 / 7	LEU A 218 ASP A 227 ALA A 226 TYR A 198	None	1.19A	3rodD-5uusA: undetectable	3rodD-5uusA: 20.35