SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 5uv6 OPIOID-BINDING
PROTEIN/CELL
ADHESION MOLECULE
(Homo
sapiens) 		4 / 8 VAL A 132
ARG A  87
ALA A  53
GLU A 110
 None
NAG  A1001 ( 4.1A)
None
None
 1.05A 1dmiA-5uv6A:
undetectable
1dmiB-5uv6A:
undetectable		 1dmiA-5uv6A:
10.73
1dmiB-5uv6A:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 5uv6 OPIOID-BINDING
PROTEIN/CELL
ADHESION MOLECULE
(Homo
sapiens) 		4 / 7 VAL A  47
LEU A 130
ARG A 162
VAL A 134
 None
 0.94A 1jgsA-5uv6A:
undetectable		 1jgsA-5uv6A:
16.31