SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		4 / 8 THR A  46
LEU A   9
VAL A  13
ASP A  50
 MG  A 302 ( 4.7A)
None
None
MG  A 302 (-2.5A)
 1.15A 1uyuB-5uvdA:
undetectable		 1uyuB-5uvdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		4 / 6 ILE A 143
ARG A 125
THR A 127
LEU A 128
 None
 1.03A 3ag1N-5uvdA:
undetectable
3ag1W-5uvdA:
undetectable		 3ag1N-5uvdA:
undetectable
3ag1W-5uvdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		4 / 8 ASP A  48
ASP A  50
GLY A  31
ARG A 154
 MG  A 302 (-2.5A)
MG  A 302 (-2.5A)
None
None
 1.03A 3s3nA-5uvdA:
undetectable		 3s3nA-5uvdA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		4 / 8 THR A  46
LEU A   9
VAL A  13
ASP A  50
 MG  A 302 ( 4.7A)
None
None
MG  A 302 (-2.5A)
 1.16A 4l4fA-5uvdA:
undetectable		 4l4fA-5uvdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		5 / 9 LEU A 196
ARG A 200
LEU A 144
ILE A 171
SER A 169
 None
 1.34A 4z69A-5uvdA:
undetectable		 4z69A-5uvdA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		5 / 12 VAL A 135
LEU A   4
GLY A  32
ALA A  33
LEU A  37
 None
None
MG  A 302 ( 4.7A)
None
None
 1.03A 5iktB-5uvdA:
undetectable		 5iktB-5uvdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvd NUCLEOTIDYLTRANSFERA
SE-LIKE PROTEIN
(Paracoccidioides
brasiliensis) 		4 / 7 ILE A 143
ARG A 125
THR A 127
LEU A 128
 None
 0.96A 6nmpA-5uvdA:
undetectable
6nmpJ-5uvdA:
undetectable		 6nmpA-5uvdA:
undetectable
6nmpJ-5uvdA:
undetectable