SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uvk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		4 / 6 HIS A 140
GLY A 141
ALA A  43
GLU A  39
 None
 0.71A 1dmaB-5uvkA:
undetectable		 1dmaB-5uvkA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		3 / 3 GLU A   7
ASP A 108
TYR A 156
 None
 0.87A 2yvlB-5uvkA:
undetectable		 2yvlB-5uvkA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		5 / 12 HIS A 140
GLY A 141
GLY A 144
ALA A 152
ASP A 155
 None
 1.04A 3keeC-5uvkA:
undetectable		 3keeC-5uvkA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		5 / 11 VAL A  95
LEU A  44
THR A  45
GLU A 149
ALA A 150
 None
 1.25A 4e0fA-5uvkA:
undetectable		 4e0fA-5uvkA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		4 / 7 HIS A 140
GLY A 141
ALA A  43
GLU A  39
 None
 0.84A 4hyfA-5uvkA:
undetectable		 4hyfA-5uvkA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		4 / 8 HIS A 140
GLY A 141
ALA A  43
GLU A  39
 None
 0.83A 4hyfB-5uvkA:
undetectable		 4hyfB-5uvkA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 5uvk C-PHYCOCYANIN ALPHA
CHAIN
(Thermosynechococ
cus
elongatus) 		4 / 8 HIS A 140
GLY A 141
ALA A  43
GLU A  39
 None
 0.81A 4hyfC-5uvkA:
undetectable		 4hyfC-5uvkA:
20.16