SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uvn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.95A 1v55C-5uvnA:
undetectable
1v55J-5uvnA:
undetectable		 1v55C-5uvnA:
20.54
1v55J-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 SER A 249
ASP A 221
SER A 245
LEU A 170
 None
 1.04A 2cdqB-5uvnA:
undetectable		 2cdqB-5uvnA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 1.00A 2eijC-5uvnA:
undetectable
2eijJ-5uvnA:
undetectable		 2eijC-5uvnA:
20.54
2eijJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.96A 2eikC-5uvnA:
undetectable
2eikJ-5uvnA:
undetectable		 2eikC-5uvnA:
20.54
2eikJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.95A 2eimC-5uvnA:
undetectable
2eimJ-5uvnA:
undetectable		 2eimC-5uvnA:
20.54
2eimJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 1.00A 2einC-5uvnA:
undetectable
2einJ-5uvnA:
undetectable		 2einC-5uvnA:
20.54
2einJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 6 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 1.05A 2einP-5uvnA:
undetectable
2einW-5uvnA:
undetectable		 2einP-5uvnA:
20.54
2einW-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 8 THR A 190
GLN A 201
ARG A 159
ILE A 161
 None
 0.83A 2xytE-5uvnA:
undetectable		 2xytE-5uvnA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 6 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 1.03A 2zxwP-5uvnA:
undetectable
2zxwW-5uvnA:
undetectable		 2zxwP-5uvnA:
20.54
2zxwW-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.96A 3ag2P-5uvnA:
undetectable
3ag2W-5uvnA:
undetectable		 3ag2P-5uvnA:
20.54
3ag2W-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.91A 3ag4P-5uvnA:
undetectable
3ag4W-5uvnA:
undetectable		 3ag4P-5uvnA:
20.54
3ag4W-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.96A 3asnC-5uvnA:
undetectable
3asnJ-5uvnA:
undetectable		 3asnC-5uvnA:
20.54
3asnJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 289
LEU A 338
SER A 316
VAL A 296
 None
 1.02A 3ozkB-5uvnA:
undetectable		 3ozkB-5uvnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.80A 3x2qC-5uvnA:
undetectable
3x2qJ-5uvnA:
undetectable		 3x2qC-5uvnA:
20.54
3x2qJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.89A 3x2qP-5uvnA:
undetectable
3x2qW-5uvnA:
undetectable		 3x2qP-5uvnA:
20.54
3x2qW-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 370
LEU A 368
ILE A 339
VAL A 305
LEU A 312
 None
 1.12A 4fr0A-5uvnA:
undetectable		 4fr0A-5uvnA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 9 PHE A 292
LEU A 386
SER A 371
VAL A 315
VAL A 337
 None
 1.16A 4wnvB-5uvnA:
undetectable		 4wnvB-5uvnA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_C_QI9C602_0
(CYTOCHROME P450 2D6)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 9 PHE A 292
ASP A 294
SER A 371
VAL A 315
VAL A 337
 None
 1.39A 4wnvC-5uvnA:
undetectable		 4wnvC-5uvnA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 5 PHE A 268
PHE A 250
PHE A 218
VAL A 212
 None
 1.04A 5a1rA-5uvnA:
undetectable		 5a1rA-5uvnA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 118
GLY A 125
GLY A 120
VAL A  72
ILE A  55
 None
 0.95A 5ehgC-5uvnA:
undetectable		 5ehgC-5uvnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 118
GLY A 125
GLY A 120
VAL A  72
ILE A  55
 None
 0.95A 5ehiA-5uvnA:
undetectable		 5ehiA-5uvnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 118
GLY A 125
GLY A 120
VAL A  72
ILE A  55
 None
 0.97A 5ehiC-5uvnA:
undetectable		 5ehiC-5uvnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 118
GLY A 125
GLY A 120
VAL A  72
ILE A  55
 None
 0.93A 5eiwA-5uvnA:
undetectable		 5eiwA-5uvnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 118
GLY A 125
GLY A 120
VAL A  72
ILE A  55
 None
 0.96A 5ekxA-5uvnA:
undetectable		 5ekxA-5uvnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 118
GLY A 125
GLY A 120
VAL A  72
ILE A  55
 None
 0.91A 5njvC-5uvnA:
undetectable		 5njvC-5uvnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		3 / 3 VAL A 186
TYR A 200
GLN A 201
 None
 0.74A 5qgkA-5uvnA:
undetectable		 5qgkA-5uvnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		3 / 3 VAL A 186
TYR A 200
GLN A 201
 None
 0.75A 5qgrA-5uvnA:
undetectable		 5qgrA-5uvnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		3 / 3 VAL A 186
TYR A 200
GLN A 201
 None
 0.76A 5qgtA-5uvnA:
undetectable		 5qgtA-5uvnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.95A 5z85C-5uvnA:
undetectable
5z85J-5uvnA:
undetectable		 5z85C-5uvnA:
20.54
5z85J-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.93A 5zcoC-5uvnA:
undetectable
5zcoJ-5uvnA:
undetectable		 5zcoC-5uvnA:
20.54
5zcoJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.97A 5zcqC-5uvnA:
undetectable
5zcqJ-5uvnA:
undetectable		 5zcqC-5uvnA:
20.54
5zcqJ-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.94A 5zcqP-5uvnA:
undetectable
5zcqW-5uvnA:
undetectable		 5zcqP-5uvnA:
20.54
5zcqW-5uvnA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5uvn PARAQUAT-INDUCIBLE
PROTEIN B
(Escherichia
coli) 		4 / 5 LEU A 202
GLN A 201
PHE A 203
PHE A 250
 None
 0.96A 6nmpP-5uvnA:
undetectable
6nmpW-5uvnA:
undetectable		 6nmpP-5uvnA:
20.54
6nmpW-5uvnA:
11.78