SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uvq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5uvq SCABIN
(Streptomyces
scabiei) 		4 / 7 ARG A  77
SER A 117
GLN A 158
GLU A 160
 None
 1.15A 2c8aA-5uvqA:
3.0		 2c8aA-5uvqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 5uvq SCABIN
(Streptomyces
scabiei) 		5 / 12 SER A 131
VAL A  85
ALA A  84
VAL A 175
VAL A 172
 None
 1.00A 2nniA-5uvqA:
undetectable		 2nniA-5uvqA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5uvq SCABIN
(Streptomyces
scabiei) 		4 / 5 ILE A 137
THR A 118
THR A 119
PHE A 163
 None
 1.07A 3snfA-5uvqA:
undetectable		 3snfA-5uvqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5uvq SCABIN
(Streptomyces
scabiei) 		4 / 5 GLY A 165
VAL A  57
PRO A 114
TYR A 106
 None
 1.11A 4grkA-5uvqA:
undetectable		 4grkA-5uvqA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 5uvq SCABIN
(Streptomyces
scabiei) 		5 / 9 VAL A 145
VAL A  49
ALA A  52
VAL A 116
ALA A 162
 None
 1.28A 4oqrA-5uvqA:
undetectable		 4oqrA-5uvqA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5uvq SCABIN
(Streptomyces
scabiei) 		3 / 3 TYR A 133
GLY A  82
PRO A  83
 None
 0.54A 4qwpA-5uvqA:
undetectable		 4qwpA-5uvqA:
14.58