SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uw8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD
(Escherichia
coli) 		5 / 9 LEU A 128
ILE A  93
VAL A  58
GLY A  66
LEU A  99
 None
 1.03A 1e7aB-5uw8A:
undetectable		 1e7aB-5uw8A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD
(Escherichia
coli) 		5 / 12 LEU A 128
ILE A  93
VAL A  58
GLY A  66
LEU A  99
 None
 1.11A 2bxeB-5uw8A:
undetectable		 2bxeB-5uw8A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD
(Escherichia
coli) 		3 / 3 TYR A  43
GLY A 131
ASP A 130
 None
 0.68A 3ou6C-5uw8A:
undetectable		 3ou6C-5uw8A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD
(Escherichia
coli) 		3 / 3 ASN A 115
ALA A 113
ARG A 102
 None
 0.77A 3tj7C-5uw8A:
undetectable
3tj7D-5uw8A:
undetectable		 3tj7C-5uw8A:
19.49
3tj7D-5uw8A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD
(Escherichia
coli) 		5 / 12 VAL A  82
GLY A  66
VAL A  58
LEU A  99
THR A 137
 None
 0.96A 4m2vA-5uw8A:
undetectable		 4m2vA-5uw8A:
17.90