SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 GLY B 369
GLN B 165
VAL B 161
ILE B 246
GLY B 164
 None
 1.37A 1fohA-5uwvB:
undetectable		 1fohA-5uwvB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 GLY B 369
GLN B 165
VAL B 161
ILE B 246
GLY B 164
 None
 1.38A 1fohB-5uwvB:
undetectable		 1fohB-5uwvB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 11 ASN B 353
MET B 277
GLY B 278
THR B 284
GLY B 329
 None
 1.13A 1jr1A-5uwvB:
undetectable		 1jr1A-5uwvB:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		4 / 8 ASN B 353
GLY B 278
THR B 284
GLY B 329
 None
 0.80A 1jr1B-5uwvB:
undetectable		 1jr1B-5uwvB:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 GLY B 369
GLN B 165
VAL B 161
ILE B 246
GLY B 164
 None
 1.34A 1pn0A-5uwvB:
undetectable		 1pn0A-5uwvB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 GLY B 369
GLN B 165
VAL B 161
ILE B 246
GLY B 164
 None
 1.36A 1pn0B-5uwvB:
undetectable		 1pn0B-5uwvB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 9 GLY B 389
ILE B 330
THR B 275
VAL B 372
VAL B 254
 None
 1.11A 2nnhB-5uwvB:
undetectable		 2nnhB-5uwvB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 12 LEU B 261
LEU B 352
MET B 277
SER B 326
LEU B 382
 None
 1.24A 2po7B-5uwvB:
undetectable		 2po7B-5uwvB:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		4 / 5 ASN B 177
ALA B 179
ALA B 180
LYS B 186
 None
 1.02A 3kp2B-5uwvB:
undetectable		 3kp2B-5uwvB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		4 / 7 ASN B 285
GLU B 386
TYR B 327
TYR B 289
 None
 1.19A 3ugrA-5uwvB:
undetectable		 3ugrA-5uwvB:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 TYR B 289
ILE B 291
VAL B 372
SER B 252
ILE B 263
 None
 0.97A 3uprA-5uwvB:
3.8		 3uprA-5uwvB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 TYR B 289
ILE B 291
VAL B 372
SER B 252
ILE B 263
 None
 0.96A 3uprC-5uwvB:
2.8		 3uprC-5uwvB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		6 / 12 TYR B 289
ILE B 291
VAL B 372
SER B 252
ILE B 263
THR B 284
 None
 1.19A 3vrjA-5uwvB:
3.9
3vrjC-5uwvB:
undetectable		 3vrjA-5uwvB:
20.98
3vrjC-5uwvB:
2.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		4 / 8 ASN B 353
GLY B 278
THR B 284
GLY B 329
 None
 0.74A 4fo4B-5uwvB:
undetectable		 4fo4B-5uwvB:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		4 / 8 SER B 348
THR B 275
THR B 377
THR B 284
 None
 1.01A 5l4eA-5uwvB:
undetectable
5l4eB-5uwvB:
undetectable
5l4eC-5uwvB:
undetectable
5l4eD-5uwvB:
undetectable
5l4eE-5uwvB:
undetectable		 5l4eA-5uwvB:
24.74
5l4eB-5uwvB:
24.74
5l4eC-5uwvB:
24.74
5l4eD-5uwvB:
24.74
5l4eE-5uwvB:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		5 / 10 TYR B 289
ILE B 291
VAL B 372
SER B 252
ILE B 263
 None
 0.98A 5u98D-5uwvB:
3.9		 5u98D-5uwvB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5uwv L,D-TRANSPEPTIDASE 2
(Mycobacteroides
abscessus) 		3 / 3 ARG B 208
ARG B 206
ASP B 390
 None
 0.91A 6d8pA-5uwvB:
undetectable		 6d8pA-5uwvB:
18.52