SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ux1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 5ux1 TRNA-(MS(2)IO(6)A)-H
YDROXYLASE-LIKE
(Synechococcus
sp.
CC9605) 		5 / 9 CYH A  52
HIS A  87
LEU A 163
LEU A 159
LEU A  46
 None
FE  A 302 (-3.2A)
None
None
None
 1.27A 1hwiA-5ux1A:
undetectable		 1hwiA-5ux1A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 5ux1 TRNA-(MS(2)IO(6)A)-H
YDROXYLASE-LIKE
(Synechococcus
sp.
CC9605) 		5 / 12 GLU A 167
HIS A 170
TYR A 174
GLU A  53
GLU A  84
 FE  A 301 ( 2.5A)
FE  A 301 (-3.3A)
None
FE  A 302 (-2.2A)
FE  A 301 ( 2.2A)
 0.94A 1rnrB-5ux1A:
12.0		 1rnrB-5ux1A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5ux1 TRNA-(MS(2)IO(6)A)-H
YDROXYLASE-LIKE
(Synechococcus
sp.
CC9605) 		4 / 6 GLY A 121
ILE A 187
TYR A 182
TYR A  67
 None
 1.03A 5iwuA-5ux1A:
undetectable		 5iwuA-5ux1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5ux1 TRNA-(MS(2)IO(6)A)-H
YDROXYLASE-LIKE
(Synechococcus
sp.
CC9605) 		4 / 7 ALA A 133
GLY A 134
GLY A 111
TYR A 110
 None
 0.85A 6nm4A-5ux1A:
undetectable		 6nm4A-5ux1A:
undetectable