SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ux5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 1c9sA-5ux5A:
undetectable
1c9sK-5ux5A:
undetectable
1c9sA-5ux5A:
5.76
1c9sK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 1c9sA-5ux5A:
undetectable
1c9sB-5ux5A:
undetectable
1c9sA-5ux5A:
5.76
1c9sB-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 1c9sB-5ux5A:
undetectable
1c9sC-5ux5A:
undetectable
1c9sB-5ux5A:
5.76
1c9sC-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 1c9sD-5ux5A:
undetectable
1c9sE-5ux5A:
undetectable
1c9sD-5ux5A:
5.76
1c9sE-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 1c9sE-5ux5A:
undetectable
1c9sF-5ux5A:
undetectable
1c9sE-5ux5A:
5.76
1c9sF-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 1c9sG-5ux5A:
undetectable
1c9sH-5ux5A:
undetectable
1c9sG-5ux5A:
5.76
1c9sH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 1c9sH-5ux5A:
undetectable
1c9sI-5ux5A:
undetectable
1c9sH-5ux5A:
5.76
1c9sI-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.20A 1c9sL-5ux5A:
undetectable
1c9sM-5ux5A:
undetectable
1c9sL-5ux5A:
5.76
1c9sM-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.18A 1c9sM-5ux5A:
undetectable
1c9sN-5ux5A:
undetectable
1c9sM-5ux5A:
5.76
1c9sN-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 1c9sN-5ux5A:
undetectable
1c9sO-5ux5A:
undetectable
1c9sN-5ux5A:
5.76
1c9sO-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.20A 1c9sO-5ux5A:
undetectable
1c9sP-5ux5A:
undetectable
1c9sO-5ux5A:
5.76
1c9sP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 1c9sQ-5ux5A:
undetectable
1c9sR-5ux5A:
undetectable
1c9sQ-5ux5A:
5.76
1c9sR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 1c9sS-5ux5A:
undetectable
1c9sT-5ux5A:
undetectable
1c9sS-5ux5A:
5.76
1c9sT-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLU A 963
ARG A 873
ARG A 882
LEU A 960
GLY A1067
None
1.08A 1cmaA-5ux5A:
undetectable
1cmaB-5ux5A:
undetectable
1cmaA-5ux5A:
7.23
1cmaB-5ux5A:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.25A 1ereA-5ux5A:
undetectable
1ereA-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.26A 1ereB-5ux5A:
undetectable
1ereB-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.26A 1ereC-5ux5A:
undetectable
1ereC-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.25A 1ereD-5ux5A:
undetectable
1ereD-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ILE A1069
GLY A1067
HIS A 850
LEU A 852
LEU A 706
None
1.43A 1fm6X-5ux5A:
undetectable
1fm6X-5ux5A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.18A 1g50A-5ux5A:
undetectable
1g50A-5ux5A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 1gtfA-5ux5A:
undetectable
1gtfB-5ux5A:
undetectable
1gtfA-5ux5A:
5.76
1gtfB-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 1gtfB-5ux5A:
undetectable
1gtfC-5ux5A:
undetectable
1gtfB-5ux5A:
5.76
1gtfC-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.20A 1gtfC-5ux5A:
undetectable
1gtfD-5ux5A:
undetectable
1gtfC-5ux5A:
5.76
1gtfD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 1gtfD-5ux5A:
undetectable
1gtfE-5ux5A:
undetectable
1gtfD-5ux5A:
5.76
1gtfE-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 1gtfE-5ux5A:
undetectable
1gtfF-5ux5A:
undetectable
1gtfE-5ux5A:
5.76
1gtfF-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 1gtfH-5ux5A:
undetectable
1gtfI-5ux5A:
undetectable
1gtfH-5ux5A:
5.76
1gtfI-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 1gtfI-5ux5A:
undetectable
1gtfJ-5ux5A:
undetectable
1gtfI-5ux5A:
5.76
1gtfJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 1gtfO-5ux5A:
undetectable
1gtfP-5ux5A:
undetectable
1gtfO-5ux5A:
5.76
1gtfP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 1gtfL-5ux5A:
undetectable
1gtfV-5ux5A:
undetectable
1gtfL-5ux5A:
5.76
1gtfV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
6 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
None
1.24A 1gtnB-5ux5A:
undetectable
1gtnC-5ux5A:
undetectable
1gtnB-5ux5A:
5.76
1gtnC-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
6 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
None
1.25A 1gtnH-5ux5A:
undetectable
1gtnI-5ux5A:
undetectable
1gtnH-5ux5A:
5.76
1gtnI-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.17A 1gtnN-5ux5A:
undetectable
1gtnO-5ux5A:
undetectable
1gtnN-5ux5A:
5.76
1gtnO-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.19A 1gtnO-5ux5A:
undetectable
1gtnP-5ux5A:
undetectable
1gtnO-5ux5A:
5.76
1gtnP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.21A 1gtnO-5ux5A:
undetectable
1gtnP-5ux5A:
undetectable
1gtnO-5ux5A:
5.76
1gtnP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 1gtnQ-5ux5A:
undetectable
1gtnR-5ux5A:
undetectable
1gtnQ-5ux5A:
5.76
1gtnR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.18A 1gtnU-5ux5A:
undetectable
1gtnV-5ux5A:
undetectable
1gtnU-5ux5A:
5.76
1gtnV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.19A 1gtnU-5ux5A:
undetectable
1gtnV-5ux5A:
undetectable
1gtnU-5ux5A:
5.76
1gtnV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 GLU A 954
ILE A 871
ARG A 968
ALA A1058
GLU A 858
None
1.20A 1ki7B-5ux5A:
undetectable
1ki7B-5ux5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 GLY A1067
GLU A 963
ARG A 873
ARG A 882
LEU A 960
None
1.16A 1mj2C-5ux5A:
undetectable
1mj2D-5ux5A:
undetectable
1mj2C-5ux5A:
7.23
1mj2D-5ux5A:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 GLY A1067
GLU A 963
ARG A 873
ARG A 882
LEU A 960
None
1.18A 1mjoC-5ux5A:
undetectable
1mjoD-5ux5A:
undetectable
1mjoC-5ux5A:
7.23
1mjoD-5ux5A:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.32A 1pcgA-5ux5A:
undetectable
1pcgA-5ux5A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.45A 1qkuB-5ux5A:
undetectable
1qkuB-5ux5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 LEU A 615
ALA A 625
VAL A 603
LEU A 607
LEU A 632
None
0.96A 1rlbF-5ux5A:
undetectable
1rlbF-5ux5A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 PRO A 884
GLY A 886
ALA A1058
SER A 892
GLU A 817
None
None
None
None
NAD  A2002 (-3.2A)
1.13A 1sg9C-5ux5A:
3.2
1sg9C-5ux5A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 601
ALA A 605
PHE A 604
ALA A 608
VAL A 586
None
1.09A 1ukbA-5ux5A:
undetectable
1ukbA-5ux5A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 1utdA-5ux5A:
undetectable
1utdB-5ux5A:
undetectable
1utdA-5ux5A:
5.76
1utdB-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.15A 1utdC-5ux5A:
undetectable
1utdD-5ux5A:
undetectable
1utdC-5ux5A:
5.76
1utdD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 1utdE-5ux5A:
undetectable
1utdF-5ux5A:
undetectable
1utdE-5ux5A:
5.76
1utdF-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 1utdA-5ux5A:
undetectable
1utdK-5ux5A:
undetectable
1utdA-5ux5A:
5.76
1utdK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 1utdM-5ux5A:
undetectable
1utdN-5ux5A:
undetectable
1utdM-5ux5A:
5.76
1utdN-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
6 / 11 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
None
SO4  A2003 (-2.4A)
None
1.24A 1utdP-5ux5A:
undetectable
1utdQ-5ux5A:
undetectable
1utdP-5ux5A:
5.76
1utdQ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.13A 1utdQ-5ux5A:
undetectable
1utdR-5ux5A:
undetectable
1utdQ-5ux5A:
5.76
1utdR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 1utdT-5ux5A:
undetectable
1utdU-5ux5A:
undetectable
1utdT-5ux5A:
5.76
1utdU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.85A 1v7zA-5ux5A:
undetectable
1v7zA-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.84A 1v7zB-5ux5A:
2.1
1v7zB-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.86A 1v7zC-5ux5A:
undetectable
1v7zC-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.86A 1v7zD-5ux5A:
undetectable
1v7zD-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.85A 1v7zE-5ux5A:
undetectable
1v7zE-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.86A 1v7zF-5ux5A:
2.4
1v7zF-5ux5A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 625
ALA A 628
LEU A 529
ALA A 558
GLU A 554
None
0.63A 2bxeA-5ux5A:
undetectable
2bxeA-5ux5A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 625
ALA A 628
LEU A 529
LEU A 600
ALA A 558
None
0.71A 2bxeA-5ux5A:
undetectable
2bxeA-5ux5A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 625
ALA A 628
LEU A 529
LEU A 600
ALA A 558
None
0.71A 2bxgB-5ux5A:
undetectable
2bxgB-5ux5A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.14A 2f16H-5ux5A:
undetectable
2f16I-5ux5A:
undetectable
2f16H-5ux5A:
13.16
2f16I-5ux5A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.14A 2f16V-5ux5A:
undetectable
2f16W-5ux5A:
undetectable
2f16V-5ux5A:
13.16
2f16W-5ux5A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ILE A 532
LEU A 632
PHE A 604
ALA A 562
ARG A 563
None
1.30A 2noaA-5ux5A:
undetectable
2noaA-5ux5A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 GLY A 392
LEU A 361
GLU A 368
ASP A 372
VAL A 345
None
0.98A 2oxtC-5ux5A:
undetectable
2oxtC-5ux5A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 7 LEU A 792
VAL A 751
GLY A 752
GLY A 763
None
0.75A 2wd9A-5ux5A:
undetectable
2wd9A-5ux5A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 LEU A 792
VAL A 751
GLY A 752
GLY A 763
None
0.76A 2wd9B-5ux5A:
undetectable
2wd9B-5ux5A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.88A 3a6jA-5ux5A:
2.4
3a6jA-5ux5A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 7 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.89A 3a6jB-5ux5A:
2.4
3a6jB-5ux5A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.88A 3a6jC-5ux5A:
2.3
3a6jC-5ux5A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.90A 3a6jE-5ux5A:
2.3
3a6jE-5ux5A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLU A 404
ASP A 405
HIS A 402
GLU A 157
None
0.88A 3a6jF-5ux5A:
2.3
3a6jF-5ux5A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 GLY A 802
VAL A 822
LEU A 776
PRO A 821
None
1.01A 3bgdB-5ux5A:
undetectable
3bgdB-5ux5A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ASN A 151
VAL A 261
VAL A 181
LEU A 175
THR A 172
None
FAD  A2001 (-4.5A)
None
None
None
1.19A 3elzA-5ux5A:
undetectable
3elzA-5ux5A:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ASN A 151
VAL A 261
VAL A 181
LEU A 175
THR A 172
None
FAD  A2001 (-4.5A)
None
None
None
1.38A 3elzC-5ux5A:
undetectable
3elzC-5ux5A:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 7 LEU A  18
LEU A 361
SER A 354
ASP A 333
None
0.99A 3lm8A-5ux5A:
2.7
3lm8C-5ux5A:
2.6
3lm8A-5ux5A:
12.30
3lm8C-5ux5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 ASP A 333
LEU A  18
LEU A 361
SER A 354
None
0.96A 3lm8B-5ux5A:
3.6
3lm8D-5ux5A:
2.7
3lm8B-5ux5A:
12.30
3lm8D-5ux5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 6 LEU A 972
PRO A 971
ARG A1013
HIS A1052
None
1.46A 3ltwA-5ux5A:
undetectable
3ltwA-5ux5A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.15A 3mg0H-5ux5A:
undetectable
3mg0I-5ux5A:
undetectable
3mg0H-5ux5A:
13.16
3mg0I-5ux5A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.15A 3mg0V-5ux5A:
undetectable
3mg0W-5ux5A:
undetectable
3mg0V-5ux5A:
13.16
3mg0W-5ux5A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 LEU A 607
LEU A 641
LEU A 585
LEU A 507
SER A 510
None
1.50A 3q1eB-5ux5A:
undetectable
3q1eD-5ux5A:
undetectable
3q1eB-5ux5A:
7.78
3q1eD-5ux5A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ASN A 531
ILE A 532
LEU A 536
ALA A 526
VAL A 555
None
0.89A 3rukA-5ux5A:
undetectable
3rukA-5ux5A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ASN A 531
ILE A 532
LEU A 536
ALA A 526
VAL A 555
None
0.86A 3rukB-5ux5A:
undetectable
3rukB-5ux5A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 GLN A 721
HIS A 718
GLY A 720
ALA A 670
GLY A 669
None
None
None
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
1.24A 3v3oB-5ux5A:
undetectable
3v3oB-5ux5A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
3 / 3 THR A 933
ASN A 932
GLU A 983
None
0.73A 3v4tA-5ux5A:
0.9
3v4tC-5ux5A:
1.0
3v4tA-5ux5A:
18.63
3v4tC-5ux5A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 6 ILE A 875
VAL A 729
LEU A 731
ILE A 697
None
0.90A 4asdA-5ux5A:
undetectable
4asdA-5ux5A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 358
ILE A 347
ILE A 293
LEU A 273
ILE A 335
None
1.19A 4dtaA-5ux5A:
undetectable
4dtaA-5ux5A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 4 LEU A 169
SER A 190
LEU A 207
LEU A 214
None
1.09A 4n09A-5ux5A:
undetectable
4n09A-5ux5A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 5 LEU A 169
SER A 190
LEU A 207
LEU A 214
None
1.09A 4n09D-5ux5A:
undetectable
4n09D-5ux5A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ASN A 531
ILE A 532
LEU A 536
ALA A 526
VAL A 555
None
0.92A 4nkvB-5ux5A:
undetectable
4nkvB-5ux5A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.11A 4qvpH-5ux5A:
undetectable
4qvpI-5ux5A:
undetectable
4qvpH-5ux5A:
13.14
4qvpI-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.11A 4qvpV-5ux5A:
undetectable
4qvpW-5ux5A:
undetectable
4qvpV-5ux5A:
13.14
4qvpW-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.14A 4qvvH-5ux5A:
undetectable
4qvvH-5ux5A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.13A 4qvvV-5ux5A:
undetectable
4qvvV-5ux5A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.13A 4qw0H-5ux5A:
undetectable
4qw0I-5ux5A:
undetectable
4qw0H-5ux5A:
13.14
4qw0I-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.13A 4qw0V-5ux5A:
undetectable
4qw0W-5ux5A:
undetectable
4qw0V-5ux5A:
13.14
4qw0W-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.14A 4qw1H-5ux5A:
undetectable
4qw1I-5ux5A:
undetectable
4qw1H-5ux5A:
13.14
4qw1I-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.14A 4qw1V-5ux5A:
undetectable
4qw1W-5ux5A:
undetectable
4qw1V-5ux5A:
13.14
4qw1W-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
3 / 3 PHE A 738
THR A 876
LEU A 823
None
0.75A 4qztA-5ux5A:
undetectable
4qztA-5ux5A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 LEU A 859
GLU A 856
LEU A 831
ASP A 853
SER A 851
None
1.48A 4r88B-5ux5A:
8.0
4r88B-5ux5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 LEU A 859
GLU A 856
LEU A 831
ASP A 853
SER A 851
None
1.48A 4r88C-5ux5A:
5.2
4r88C-5ux5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 LEU A 859
GLU A 856
LEU A 831
ASP A 853
SER A 851
None
1.47A 4r88D-5ux5A:
7.9
4r88D-5ux5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 LEU A 859
GLU A 856
LEU A 831
ASP A 853
SER A 851
None
1.49A 4r88E-5ux5A:
7.5
4r88E-5ux5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 LEU A 859
GLU A 856
LEU A 831
ASP A 853
SER A 851
None
1.49A 4r88F-5ux5A:
2.6
4r88F-5ux5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
3 / 3 ARG A 330
GLN A 274
GLU A 454
None
0.93A 4tvtA-5ux5A:
undetectable
4tvtA-5ux5A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 4 VAL A 729
ALA A 695
ASN A 694
GLN A 838
None
1.34A 4zgfA-5ux5A:
undetectable
4zgfA-5ux5A:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 GLY A 717
GLY A 720
GLY A 820
GLU A 550
ALA A 549
None
0.96A 5c0oF-5ux5A:
3.1
5c0oF-5ux5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.13A 5cz7V-5ux5A:
undetectable
5cz7W-5ux5A:
undetectable
5cz7V-5ux5A:
13.14
5cz7W-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.14A 5d0xV-5ux5A:
undetectable
5d0xV-5ux5A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eeuC-5ux5A:
undetectable
5eeuD-5ux5A:
undetectable
5eeuC-5ux5A:
5.76
5eeuD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eeuF-5ux5A:
undetectable
5eeuG-5ux5A:
undetectable
5eeuF-5ux5A:
5.76
5eeuG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eeuF-5ux5A:
undetectable
5eeuG-5ux5A:
undetectable
5eeuF-5ux5A:
5.76
5eeuG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.28A 5eeuG-5ux5A:
undetectable
5eeuH-5ux5A:
undetectable
5eeuG-5ux5A:
5.76
5eeuH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5eeuG-5ux5A:
undetectable
5eeuH-5ux5A:
undetectable
5eeuG-5ux5A:
5.76
5eeuH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eeuI-5ux5A:
undetectable
5eeuJ-5ux5A:
undetectable
5eeuI-5ux5A:
5.76
5eeuJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eeuI-5ux5A:
undetectable
5eeuJ-5ux5A:
undetectable
5eeuI-5ux5A:
5.76
5eeuJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eeuJ-5ux5A:
undetectable
5eeuK-5ux5A:
undetectable
5eeuJ-5ux5A:
5.76
5eeuK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.15A 5eeuA-5ux5A:
undetectable
5eeuK-5ux5A:
undetectable
5eeuA-5ux5A:
5.76
5eeuK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5eeuO-5ux5A:
undetectable
5eeuP-5ux5A:
undetectable
5eeuO-5ux5A:
5.76
5eeuP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.18A 5eeuO-5ux5A:
undetectable
5eeuP-5ux5A:
undetectable
5eeuO-5ux5A:
5.76
5eeuP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
6 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
None
SO4  A2003 (-2.4A)
None
1.23A 5eeuQ-5ux5A:
undetectable
5eeuR-5ux5A:
undetectable
5eeuQ-5ux5A:
5.76
5eeuR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.18A 5eeuT-5ux5A:
undetectable
5eeuU-5ux5A:
undetectable
5eeuT-5ux5A:
5.76
5eeuU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5eeuU-5ux5A:
undetectable
5eeuV-5ux5A:
undetectable
5eeuU-5ux5A:
5.76
5eeuV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5eeuU-5ux5A:
undetectable
5eeuV-5ux5A:
undetectable
5eeuU-5ux5A:
5.76
5eeuV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eevC-5ux5A:
undetectable
5eevD-5ux5A:
undetectable
5eevC-5ux5A:
5.76
5eevD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5eevF-5ux5A:
undetectable
5eevG-5ux5A:
undetectable
5eevF-5ux5A:
5.76
5eevG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eevF-5ux5A:
undetectable
5eevG-5ux5A:
undetectable
5eevF-5ux5A:
5.76
5eevG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5eevG-5ux5A:
undetectable
5eevH-5ux5A:
undetectable
5eevG-5ux5A:
5.76
5eevH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5eevG-5ux5A:
undetectable
5eevH-5ux5A:
undetectable
5eevG-5ux5A:
5.76
5eevH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eevI-5ux5A:
undetectable
5eevJ-5ux5A:
undetectable
5eevI-5ux5A:
5.76
5eevJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eevI-5ux5A:
undetectable
5eevJ-5ux5A:
undetectable
5eevI-5ux5A:
5.76
5eevJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eevJ-5ux5A:
undetectable
5eevK-5ux5A:
undetectable
5eevJ-5ux5A:
5.76
5eevK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.15A 5eevA-5ux5A:
undetectable
5eevK-5ux5A:
undetectable
5eevA-5ux5A:
5.76
5eevK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5eevO-5ux5A:
undetectable
5eevP-5ux5A:
undetectable
5eevO-5ux5A:
5.76
5eevP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 5eevO-5ux5A:
undetectable
5eevP-5ux5A:
undetectable
5eevO-5ux5A:
5.76
5eevP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
6 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
None
SO4  A2003 (-2.4A)
None
1.23A 5eevQ-5ux5A:
undetectable
5eevR-5ux5A:
undetectable
5eevQ-5ux5A:
5.76
5eevR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eevT-5ux5A:
undetectable
5eevU-5ux5A:
undetectable
5eevT-5ux5A:
5.76
5eevU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5eevU-5ux5A:
undetectable
5eevV-5ux5A:
undetectable
5eevU-5ux5A:
5.76
5eevV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5eevU-5ux5A:
undetectable
5eevV-5ux5A:
undetectable
5eevU-5ux5A:
5.76
5eevV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eewC-5ux5A:
undetectable
5eewD-5ux5A:
undetectable
5eewC-5ux5A:
5.76
5eewD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eewF-5ux5A:
undetectable
5eewG-5ux5A:
undetectable
5eewF-5ux5A:
5.76
5eewG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eewF-5ux5A:
undetectable
5eewG-5ux5A:
undetectable
5eewF-5ux5A:
5.76
5eewG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5eewG-5ux5A:
undetectable
5eewH-5ux5A:
undetectable
5eewG-5ux5A:
5.76
5eewH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5eewG-5ux5A:
undetectable
5eewH-5ux5A:
undetectable
5eewG-5ux5A:
5.76
5eewH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eewI-5ux5A:
undetectable
5eewJ-5ux5A:
undetectable
5eewI-5ux5A:
5.76
5eewJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eewI-5ux5A:
undetectable
5eewJ-5ux5A:
undetectable
5eewI-5ux5A:
5.76
5eewJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eewJ-5ux5A:
undetectable
5eewK-5ux5A:
undetectable
5eewJ-5ux5A:
5.76
5eewK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.15A 5eewA-5ux5A:
undetectable
5eewK-5ux5A:
undetectable
5eewA-5ux5A:
5.76
5eewK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.21A 5eewO-5ux5A:
undetectable
5eewP-5ux5A:
undetectable
5eewO-5ux5A:
5.76
5eewP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 5eewO-5ux5A:
undetectable
5eewP-5ux5A:
undetectable
5eewO-5ux5A:
5.76
5eewP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
6 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
None
SO4  A2003 (-2.4A)
None
1.23A 5eewQ-5ux5A:
undetectable
5eewR-5ux5A:
undetectable
5eewQ-5ux5A:
5.76
5eewR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eewT-5ux5A:
undetectable
5eewU-5ux5A:
undetectable
5eewT-5ux5A:
5.76
5eewU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5eewU-5ux5A:
undetectable
5eewV-5ux5A:
undetectable
5eewU-5ux5A:
5.76
5eewV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5eewU-5ux5A:
undetectable
5eewV-5ux5A:
undetectable
5eewU-5ux5A:
5.76
5eewV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eexC-5ux5A:
undetectable
5eexD-5ux5A:
undetectable
5eexC-5ux5A:
5.76
5eexD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eexF-5ux5A:
undetectable
5eexG-5ux5A:
undetectable
5eexF-5ux5A:
5.76
5eexG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eexF-5ux5A:
undetectable
5eexG-5ux5A:
undetectable
5eexF-5ux5A:
5.76
5eexG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5eexG-5ux5A:
undetectable
5eexH-5ux5A:
undetectable
5eexG-5ux5A:
5.76
5eexH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eexG-5ux5A:
undetectable
5eexH-5ux5A:
undetectable
5eexG-5ux5A:
5.76
5eexH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5eexI-5ux5A:
undetectable
5eexJ-5ux5A:
undetectable
5eexI-5ux5A:
5.76
5eexJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eexI-5ux5A:
undetectable
5eexJ-5ux5A:
undetectable
5eexI-5ux5A:
5.76
5eexJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eexJ-5ux5A:
undetectable
5eexK-5ux5A:
undetectable
5eexJ-5ux5A:
5.76
5eexK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.32A 5eexA-5ux5A:
undetectable
5eexK-5ux5A:
undetectable
5eexA-5ux5A:
5.76
5eexK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.15A 5eexA-5ux5A:
undetectable
5eexK-5ux5A:
undetectable
5eexA-5ux5A:
5.76
5eexK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5eexO-5ux5A:
undetectable
5eexP-5ux5A:
undetectable
5eexO-5ux5A:
5.76
5eexP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 5eexO-5ux5A:
undetectable
5eexP-5ux5A:
undetectable
5eexO-5ux5A:
5.76
5eexP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eexQ-5ux5A:
undetectable
5eexR-5ux5A:
undetectable
5eexQ-5ux5A:
5.76
5eexR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eexT-5ux5A:
undetectable
5eexU-5ux5A:
undetectable
5eexT-5ux5A:
5.76
5eexU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5eexU-5ux5A:
undetectable
5eexV-5ux5A:
undetectable
5eexU-5ux5A:
5.76
5eexV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eexU-5ux5A:
undetectable
5eexV-5ux5A:
undetectable
5eexU-5ux5A:
5.76
5eexV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.15A 5eeyC-5ux5A:
undetectable
5eeyD-5ux5A:
undetectable
5eeyC-5ux5A:
5.76
5eeyD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eeyF-5ux5A:
undetectable
5eeyG-5ux5A:
undetectable
5eeyF-5ux5A:
5.76
5eeyG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eeyF-5ux5A:
undetectable
5eeyG-5ux5A:
undetectable
5eeyF-5ux5A:
5.76
5eeyG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5eeyG-5ux5A:
undetectable
5eeyH-5ux5A:
undetectable
5eeyG-5ux5A:
5.76
5eeyH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eeyG-5ux5A:
undetectable
5eeyH-5ux5A:
undetectable
5eeyG-5ux5A:
5.76
5eeyH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5eeyI-5ux5A:
undetectable
5eeyJ-5ux5A:
undetectable
5eeyI-5ux5A:
5.76
5eeyJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eeyI-5ux5A:
undetectable
5eeyJ-5ux5A:
undetectable
5eeyI-5ux5A:
5.76
5eeyJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eeyJ-5ux5A:
undetectable
5eeyK-5ux5A:
undetectable
5eeyJ-5ux5A:
5.76
5eeyK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.15A 5eeyA-5ux5A:
undetectable
5eeyK-5ux5A:
undetectable
5eeyA-5ux5A:
5.76
5eeyK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5eeyO-5ux5A:
undetectable
5eeyP-5ux5A:
undetectable
5eeyO-5ux5A:
5.76
5eeyP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 5eeyO-5ux5A:
undetectable
5eeyP-5ux5A:
undetectable
5eeyO-5ux5A:
5.76
5eeyP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eeyQ-5ux5A:
undetectable
5eeyR-5ux5A:
undetectable
5eeyQ-5ux5A:
5.76
5eeyR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eeyT-5ux5A:
undetectable
5eeyU-5ux5A:
undetectable
5eeyT-5ux5A:
5.76
5eeyU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5eeyU-5ux5A:
undetectable
5eeyV-5ux5A:
undetectable
5eeyU-5ux5A:
5.76
5eeyV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eeyU-5ux5A:
undetectable
5eeyV-5ux5A:
undetectable
5eeyU-5ux5A:
5.76
5eeyV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eezC-5ux5A:
undetectable
5eezD-5ux5A:
undetectable
5eezC-5ux5A:
5.76
5eezD-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eezF-5ux5A:
undetectable
5eezG-5ux5A:
undetectable
5eezF-5ux5A:
5.76
5eezG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5eezF-5ux5A:
undetectable
5eezG-5ux5A:
undetectable
5eezF-5ux5A:
5.76
5eezG-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.28A 5eezG-5ux5A:
undetectable
5eezH-5ux5A:
undetectable
5eezG-5ux5A:
5.76
5eezH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5eezG-5ux5A:
undetectable
5eezH-5ux5A:
undetectable
5eezG-5ux5A:
5.76
5eezH-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5eezI-5ux5A:
undetectable
5eezJ-5ux5A:
undetectable
5eezI-5ux5A:
5.76
5eezJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5eezI-5ux5A:
undetectable
5eezJ-5ux5A:
undetectable
5eezI-5ux5A:
5.76
5eezJ-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5eezJ-5ux5A:
undetectable
5eezK-5ux5A:
undetectable
5eezJ-5ux5A:
5.76
5eezK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5eezA-5ux5A:
undetectable
5eezK-5ux5A:
undetectable
5eezA-5ux5A:
5.76
5eezK-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5eezO-5ux5A:
undetectable
5eezP-5ux5A:
undetectable
5eezO-5ux5A:
5.76
5eezP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 5eezO-5ux5A:
undetectable
5eezP-5ux5A:
undetectable
5eezO-5ux5A:
5.76
5eezP-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eezQ-5ux5A:
undetectable
5eezR-5ux5A:
undetectable
5eezQ-5ux5A:
5.76
5eezR-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eezT-5ux5A:
undetectable
5eezU-5ux5A:
undetectable
5eezT-5ux5A:
5.76
5eezU-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5eezU-5ux5A:
undetectable
5eezV-5ux5A:
undetectable
5eezU-5ux5A:
5.76
5eezV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5eezU-5ux5A:
undetectable
5eezV-5ux5A:
undetectable
5eezU-5ux5A:
5.76
5eezV-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef0C-5ux5A:
undetectable
5ef0D-5ux5A:
undetectable
5ef0C-5ux5A:
5.76
5ef0D-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5ef0F-5ux5A:
undetectable
5ef0G-5ux5A:
undetectable
5ef0F-5ux5A:
5.76
5ef0G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef0F-5ux5A:
undetectable
5ef0G-5ux5A:
undetectable
5ef0F-5ux5A:
5.76
5ef0G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.28A 5ef0G-5ux5A:
undetectable
5ef0H-5ux5A:
undetectable
5ef0G-5ux5A:
5.76
5ef0H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5ef0G-5ux5A:
undetectable
5ef0H-5ux5A:
undetectable
5ef0G-5ux5A:
5.76
5ef0H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5ef0I-5ux5A:
undetectable
5ef0J-5ux5A:
undetectable
5ef0I-5ux5A:
5.76
5ef0J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef0I-5ux5A:
undetectable
5ef0J-5ux5A:
undetectable
5ef0I-5ux5A:
5.76
5ef0J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5ef0J-5ux5A:
undetectable
5ef0K-5ux5A:
undetectable
5ef0J-5ux5A:
5.76
5ef0K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.31A 5ef0A-5ux5A:
undetectable
5ef0K-5ux5A:
undetectable
5ef0A-5ux5A:
5.76
5ef0K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5ef0A-5ux5A:
undetectable
5ef0K-5ux5A:
undetectable
5ef0A-5ux5A:
5.76
5ef0K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5ef0O-5ux5A:
undetectable
5ef0P-5ux5A:
undetectable
5ef0O-5ux5A:
5.76
5ef0P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.19A 5ef0O-5ux5A:
undetectable
5ef0P-5ux5A:
undetectable
5ef0O-5ux5A:
5.76
5ef0P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef0Q-5ux5A:
undetectable
5ef0R-5ux5A:
undetectable
5ef0Q-5ux5A:
5.76
5ef0R-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef0T-5ux5A:
undetectable
5ef0U-5ux5A:
undetectable
5ef0T-5ux5A:
5.76
5ef0U-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5ef0U-5ux5A:
undetectable
5ef0V-5ux5A:
undetectable
5ef0U-5ux5A:
5.76
5ef0V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef0U-5ux5A:
undetectable
5ef0V-5ux5A:
undetectable
5ef0U-5ux5A:
5.76
5ef0V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef1C-5ux5A:
undetectable
5ef1D-5ux5A:
undetectable
5ef1C-5ux5A:
5.76
5ef1D-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef1F-5ux5A:
undetectable
5ef1G-5ux5A:
undetectable
5ef1F-5ux5A:
5.76
5ef1G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef1F-5ux5A:
undetectable
5ef1G-5ux5A:
undetectable
5ef1F-5ux5A:
5.76
5ef1G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5ef1G-5ux5A:
undetectable
5ef1H-5ux5A:
undetectable
5ef1G-5ux5A:
5.76
5ef1H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5ef1G-5ux5A:
undetectable
5ef1H-5ux5A:
undetectable
5ef1G-5ux5A:
5.76
5ef1H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5ef1I-5ux5A:
undetectable
5ef1J-5ux5A:
undetectable
5ef1I-5ux5A:
5.76
5ef1J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef1I-5ux5A:
undetectable
5ef1J-5ux5A:
undetectable
5ef1I-5ux5A:
5.76
5ef1J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5ef1J-5ux5A:
undetectable
5ef1K-5ux5A:
undetectable
5ef1J-5ux5A:
5.76
5ef1K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5ef1A-5ux5A:
undetectable
5ef1K-5ux5A:
undetectable
5ef1A-5ux5A:
5.76
5ef1K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.21A 5ef1O-5ux5A:
undetectable
5ef1P-5ux5A:
undetectable
5ef1O-5ux5A:
5.76
5ef1P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5ef1O-5ux5A:
undetectable
5ef1P-5ux5A:
undetectable
5ef1O-5ux5A:
5.76
5ef1P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef1Q-5ux5A:
undetectable
5ef1R-5ux5A:
undetectable
5ef1Q-5ux5A:
5.76
5ef1R-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef1T-5ux5A:
undetectable
5ef1U-5ux5A:
undetectable
5ef1T-5ux5A:
5.76
5ef1U-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.25A 5ef1U-5ux5A:
undetectable
5ef1V-5ux5A:
undetectable
5ef1U-5ux5A:
5.76
5ef1V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef1U-5ux5A:
undetectable
5ef1V-5ux5A:
undetectable
5ef1U-5ux5A:
5.76
5ef1V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef2C-5ux5A:
undetectable
5ef2D-5ux5A:
undetectable
5ef2C-5ux5A:
5.76
5ef2D-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef2F-5ux5A:
undetectable
5ef2G-5ux5A:
undetectable
5ef2F-5ux5A:
5.76
5ef2G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef2F-5ux5A:
undetectable
5ef2G-5ux5A:
undetectable
5ef2F-5ux5A:
5.76
5ef2G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5ef2G-5ux5A:
undetectable
5ef2H-5ux5A:
undetectable
5ef2G-5ux5A:
5.76
5ef2H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef2G-5ux5A:
undetectable
5ef2H-5ux5A:
undetectable
5ef2G-5ux5A:
5.76
5ef2H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5ef2I-5ux5A:
undetectable
5ef2J-5ux5A:
undetectable
5ef2I-5ux5A:
5.76
5ef2J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef2I-5ux5A:
undetectable
5ef2J-5ux5A:
undetectable
5ef2I-5ux5A:
5.76
5ef2J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5ef2J-5ux5A:
undetectable
5ef2K-5ux5A:
undetectable
5ef2J-5ux5A:
5.76
5ef2K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5ef2A-5ux5A:
undetectable
5ef2K-5ux5A:
undetectable
5ef2A-5ux5A:
5.76
5ef2K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5ef2O-5ux5A:
undetectable
5ef2P-5ux5A:
undetectable
5ef2O-5ux5A:
5.76
5ef2P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5ef2O-5ux5A:
undetectable
5ef2P-5ux5A:
undetectable
5ef2O-5ux5A:
5.76
5ef2P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef2Q-5ux5A:
undetectable
5ef2R-5ux5A:
undetectable
5ef2Q-5ux5A:
5.76
5ef2R-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef2T-5ux5A:
undetectable
5ef2U-5ux5A:
undetectable
5ef2T-5ux5A:
5.76
5ef2U-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.24A 5ef2U-5ux5A:
undetectable
5ef2V-5ux5A:
undetectable
5ef2U-5ux5A:
5.76
5ef2V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef2U-5ux5A:
undetectable
5ef2V-5ux5A:
undetectable
5ef2U-5ux5A:
5.76
5ef2V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.16A 5ef3C-5ux5A:
undetectable
5ef3D-5ux5A:
undetectable
5ef3C-5ux5A:
5.76
5ef3D-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
ALA A 725
GLY A 874
ALA A 726
THR A 846
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef3F-5ux5A:
undetectable
5ef3G-5ux5A:
undetectable
5ef3F-5ux5A:
5.76
5ef3G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef3F-5ux5A:
undetectable
5ef3G-5ux5A:
undetectable
5ef3F-5ux5A:
5.76
5ef3G-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.27A 5ef3G-5ux5A:
undetectable
5ef3H-5ux5A:
undetectable
5ef3G-5ux5A:
5.76
5ef3H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.19A 5ef3G-5ux5A:
undetectable
5ef3H-5ux5A:
undetectable
5ef3G-5ux5A:
5.76
5ef3H-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.30A 5ef3I-5ux5A:
undetectable
5ef3J-5ux5A:
undetectable
5ef3I-5ux5A:
5.76
5ef3J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.17A 5ef3I-5ux5A:
undetectable
5ef3J-5ux5A:
undetectable
5ef3I-5ux5A:
5.76
5ef3J-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 SER A 724
GLY A 874
ALA A 726
THR A 846
ILE A 696
SO4  A2003 (-2.4A)
None
None
None
None
1.18A 5ef3J-5ux5A:
undetectable
5ef3K-5ux5A:
undetectable
5ef3J-5ux5A:
5.76
5ef3K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.31A 5ef3A-5ux5A:
undetectable
5ef3K-5ux5A:
undetectable
5ef3A-5ux5A:
5.76
5ef3K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.16A 5ef3A-5ux5A:
undetectable
5ef3K-5ux5A:
undetectable
5ef3A-5ux5A:
5.76
5ef3K-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 726
THR A 846
ILE A 696
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.21A 5ef3O-5ux5A:
undetectable
5ef3P-5ux5A:
undetectable
5ef3O-5ux5A:
5.76
5ef3P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
SER A 724
ALA A 725
None
None
None
SO4  A2003 (-2.4A)
None
1.20A 5ef3O-5ux5A:
undetectable
5ef3P-5ux5A:
undetectable
5ef3O-5ux5A:
5.76
5ef3P-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef3Q-5ux5A:
undetectable
5ef3R-5ux5A:
undetectable
5ef3Q-5ux5A:
5.76
5ef3R-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.17A 5ef3T-5ux5A:
undetectable
5ef3U-5ux5A:
undetectable
5ef3T-5ux5A:
5.76
5ef3U-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 538
HIS A 542
ALA A 481
HIS A 755
THR A 541
None
1.25A 5ef3U-5ux5A:
undetectable
5ef3V-5ux5A:
undetectable
5ef3U-5ux5A:
5.76
5ef3V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 GLY A 874
ALA A 726
THR A 846
ILE A 696
SER A 724
None
None
None
None
SO4  A2003 (-2.4A)
1.18A 5ef3U-5ux5A:
undetectable
5ef3V-5ux5A:
undetectable
5ef3U-5ux5A:
5.76
5ef3V-5ux5A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 4 VAL A 807
GLU A 783
GLY A 824
LEU A 728
None
1.39A 5g5gC-5ux5A:
undetectable
5g5gC-5ux5A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 TYR A 904
ALA A 878
GLY A 602
PHE A 561
GLY A 900
None
SO4  A2003 (-3.4A)
None
None
None
1.28A 5i71A-5ux5A:
undetectable
5i71A-5ux5A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.11A 5l5fH-5ux5A:
undetectable
5l5fI-5ux5A:
undetectable
5l5fH-5ux5A:
13.14
5l5fI-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.11A 5l5fV-5ux5A:
undetectable
5l5fW-5ux5A:
undetectable
5l5fV-5ux5A:
13.14
5l5fW-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.11A 5l66H-5ux5A:
undetectable
5l66I-5ux5A:
undetectable
5l66H-5ux5A:
13.14
5l66I-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 THR A 673
ALA A 670
GLY A 669
THR A 668
ALA A 688
NAD  A2002 (-2.9A)
NAD  A2002 (-3.5A)
NAD  A2002 (-3.3A)
None
None
1.11A 5l66V-5ux5A:
undetectable
5l66W-5ux5A:
undetectable
5l66V-5ux5A:
13.14
5l66W-5ux5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 ALA A 188
VAL A 191
LEU A 169
ILE A 227
None
0.69A 5nujA-5ux5A:
undetectable
5nujA-5ux5A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 HIS A 827
ALA A 726
GLY A 874
ILE A 875
ALA A 695
None
1.30A 5vyhA-5ux5A:
undetectable
5vyhA-5ux5A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 TYR A 565
ILE A 598
PHE A 885
GLY A 900
GLY A 602
None
None
SO4  A2003 (-4.2A)
None
None
1.32A 6awoA-5ux5A:
1.7
6awoA-5ux5A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 9 TYR A 565
ILE A 598
PHE A 885
GLY A 900
GLY A 602
None
None
SO4  A2003 (-4.2A)
None
None
1.32A 6awqA-5ux5A:
1.7
6awqA-5ux5A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 PRO A 489
GLU A 543
PRO A 591
ALA A 618
ALA A 589
None
None
None
NAD  A2002 (-3.9A)
NAD  A2002 ( 3.9A)
1.37A 6bm5A-5ux5A:
undetectable
6bm5A-5ux5A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 ILE A 559
ASP A 560
VAL A 880
ALA A 525
LEU A 600
None
1.11A 6bq4B-5ux5A:
3.6
6bq4B-5ux5A:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 10 ALA A 625
GLU A 626
LEU A 644
ILE A 637
LEU A 600
None
1.33A 6cbzB-5ux5A:
undetectable
6cbzB-5ux5A:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_A_GM4A301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 11 VAL A 711
ALA A 715
LEU A 731
ASP A 805
ALA A 726
None
1.32A 6dk1A-5ux5A:
undetectable
6dk1A-5ux5A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 VAL A 373
ASP A 372
LEU A  15
LEU A  18
LEU A 329
None
1.09A 6ew0B-5ux5A:
undetectable
6ew0B-5ux5A:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 VAL A 373
ASP A 372
LEU A  15
LEU A  18
LEU A 329
None
1.10A 6ew0D-5ux5A:
undetectable
6ew0D-5ux5A:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 VAL A 373
ASP A 372
LEU A  15
LEU A  18
LEU A 329
None
1.09A 6ew0H-5ux5A:
undetectable
6ew0H-5ux5A:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
5 / 12 VAL A 373
ASP A 372
LEU A  15
LEU A  18
LEU A 329
None
1.09A 6ew0I-5ux5A:
undetectable
6ew0I-5ux5A:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense)
4 / 8 ALA A 628
LEU A 529
ALA A 558
GLU A 554
None
0.69A 6mdqA-5ux5A:
undetectable
6mdqA-5ux5A:
5.47