SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ux9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		3 / 3 VAL A 182
TRP A 185
TRP A 188
 None
 1.23A 1c4dA-5ux9A:
undetectable
1c4dB-5ux9A:
undetectable		 1c4dA-5ux9A:
5.45
1c4dB-5ux9A:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 12 TYR A 158
ASP A 124
GLN A 210
GLU A 206
ILE A 183
 None
 1.20A 1fkbA-5ux9A:
undetectable		 1fkbA-5ux9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 12 GLY A  79
ALA A  80
ILE A 145
GLY A 146
ILE A  76
 None
 0.80A 1hxbA-5ux9A:
undetectable		 1hxbA-5ux9A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 11 GLY A 163
ALA A 149
ILE A 127
ALA A 143
ILE A 145
 None
 1.02A 2b60B-5ux9A:
undetectable		 2b60B-5ux9A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 12 ALA A 149
VAL A 137
ASN A 165
GLY A 146
ILE A 145
 None
 1.42A 2dcfA-5ux9A:
undetectable		 2dcfA-5ux9A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 9 ALA A 149
ALA A  80
GLY A  79
GLY A 128
ILE A 127
 None
 1.05A 2v7bA-5ux9A:
undetectable		 2v7bA-5ux9A:
17.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		3 / 3 GLY A  10
TYR A  29
SER A  31
 None
 0.64A 2xatA-5ux9A:
23.4		 2xatA-5ux9A:
49.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 12 GLY A  79
ALA A  80
ILE A 145
GLY A 146
ILE A  76
 None
 0.84A 3cyxB-5ux9A:
undetectable		 3cyxB-5ux9A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 9 ALA A 149
ALA A  80
GLY A  79
GLY A 128
ILE A 127
 None
 1.05A 4eatB-5ux9A:
undetectable		 4eatB-5ux9A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		4 / 7 GLU A 174
PHE A 172
LYS A 170
TYR A 158
 None
 1.16A 4uciB-5ux9A:
undetectable		 4uciB-5ux9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5ux9 CHLORAMPHENICOL
ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 11 ILE A 139
ILE A 145
VAL A 121
ILE A  76
ALA A  80
 None
 1.05A 5lg3A-5ux9A:
undetectable		 5lg3A-5ux9A:
19.06