SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uxi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5uxi ALDEHYDE
DECARBONYLASE
(Nostoc
punctiforme) 		5 / 9 TYR A  18
LEU A  75
VAL A  77
GLY A  72
ILE A  25
 None
None
None
None
DDQ  A 302 (-4.3A)
 1.12A 2a1oB-5uxiA:
undetectable		 2a1oB-5uxiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5uxi ALDEHYDE
DECARBONYLASE
(Nostoc
punctiforme) 		4 / 7 SER A 212
ARG A 223
LEU A 224
GLU A 168
 None
 0.96A 2cdqB-5uxiA:
undetectable		 2cdqB-5uxiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 5uxi ALDEHYDE
DECARBONYLASE
(Nostoc
punctiforme) 		4 / 7 ASN A 171
LEU A 167
GLY A 208
SER A 212
 None
 1.02A 4cp3A-5uxiA:
undetectable
4cp3B-5uxiA:
undetectable		 4cp3A-5uxiA:
23.93
4cp3B-5uxiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5uxi ALDEHYDE
DECARBONYLASE
(Nostoc
punctiforme) 		5 / 7 GLU A 195
LYS A 196
LEU A 199
ASN A 183
LEU A 182
 None
None
DDQ  A 302 ( 4.5A)
None
None
 1.24A 4wg0B-5uxiA:
undetectable
4wg0C-5uxiA:
undetectable		 4wg0B-5uxiA:
undetectable
4wg0C-5uxiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 5uxi ALDEHYDE
DECARBONYLASE
(Nostoc
punctiforme) 		5 / 9 GLY A  32
GLU A  38
ASN A  39
ILE A 115
ALA A 119
 DDQ  A 300 ( 4.0A)
None
None
None
DDQ  A 301 ( 3.5A)
 1.07A 5entC-5uxiA:
undetectable		 5entC-5uxiA:
9.98