SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uxv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 ALA A 253
GLN A 252
LEU A 249
LEU A 254
ILE A 144
 None
 1.00A 2aclA-5uxvA:
undetectable
2aclE-5uxvA:
undetectable		 2aclA-5uxvA:
19.67
2aclE-5uxvA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		4 / 5 PHE A 256
THR A 234
LEU A 249
ALA A 253
 None
 1.14A 2e1qD-5uxvA:
undetectable		 2e1qD-5uxvA:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 11 ASP A  65
SER A  89
LEU A 127
PHE A  99
ILE A 102
 None
 1.03A 3ko0A-5uxvA:
undetectable
3ko0B-5uxvA:
undetectable
3ko0C-5uxvA:
undetectable
3ko0D-5uxvA:
undetectable		 3ko0A-5uxvA:
17.59
3ko0B-5uxvA:
17.59
3ko0C-5uxvA:
17.59
3ko0D-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 11 ASP A  65
SER A  89
LEU A 127
PHE A  99
ILE A 102
 None
 1.01A 3ko0C-5uxvA:
undetectable
3ko0D-5uxvA:
undetectable
3ko0E-5uxvA:
undetectable
3ko0F-5uxvA:
undetectable		 3ko0C-5uxvA:
17.59
3ko0D-5uxvA:
17.59
3ko0E-5uxvA:
17.59
3ko0F-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 11 LEU A 127
PHE A  99
ILE A 102
ASP A  65
SER A  89
 None
 1.06A 3ko0E-5uxvA:
undetectable
3ko0F-5uxvA:
undetectable
3ko0G-5uxvA:
undetectable
3ko0H-5uxvA:
undetectable		 3ko0E-5uxvA:
17.59
3ko0F-5uxvA:
17.59
3ko0G-5uxvA:
17.59
3ko0H-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 LEU A 127
PHE A  99
ILE A 102
ASP A  65
SER A  89
 None
 1.04A 3ko0G-5uxvA:
undetectable
3ko0H-5uxvA:
undetectable
3ko0I-5uxvA:
undetectable
3ko0J-5uxvA:
undetectable		 3ko0G-5uxvA:
17.59
3ko0H-5uxvA:
17.59
3ko0I-5uxvA:
17.59
3ko0J-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 ASP A  65
SER A  89
LEU A 127
PHE A  99
ILE A 102
 None
 1.00A 3ko0G-5uxvA:
undetectable
3ko0H-5uxvA:
undetectable
3ko0I-5uxvA:
undetectable
3ko0J-5uxvA:
undetectable		 3ko0G-5uxvA:
17.59
3ko0H-5uxvA:
17.59
3ko0I-5uxvA:
17.59
3ko0J-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 LEU A 127
PHE A  99
ILE A 102
ASP A  65
SER A  89
 None
 1.02A 3ko0M-5uxvA:
undetectable
3ko0N-5uxvA:
undetectable
3ko0O-5uxvA:
undetectable
3ko0P-5uxvA:
undetectable		 3ko0M-5uxvA:
17.59
3ko0N-5uxvA:
17.59
3ko0O-5uxvA:
17.59
3ko0P-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 11 LEU A 127
PHE A  99
ILE A 102
ASP A  65
SER A  89
 None
 0.99A 3ko0O-5uxvA:
undetectable
3ko0P-5uxvA:
undetectable
3ko0Q-5uxvA:
undetectable
3ko0R-5uxvA:
undetectable		 3ko0O-5uxvA:
17.59
3ko0P-5uxvA:
17.59
3ko0Q-5uxvA:
17.59
3ko0R-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 ASP A  65
SER A  89
LEU A 127
PHE A  99
ILE A 102
 None
 1.03A 3ko0M-5uxvA:
undetectable
3ko0N-5uxvA:
undetectable
3ko0O-5uxvA:
undetectable
3ko0P-5uxvA:
undetectable		 3ko0M-5uxvA:
17.59
3ko0N-5uxvA:
17.59
3ko0O-5uxvA:
17.59
3ko0P-5uxvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 MET A 245
VAL A 104
ARG A  53
LEU A 249
ILE A 192
 None
 1.25A 3mnoA-5uxvA:
undetectable		 3mnoA-5uxvA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 12 MET A 245
VAL A 104
ARG A  53
LEU A 249
ILE A 192
 None
 1.23A 3mnpA-5uxvA:
undetectable		 3mnpA-5uxvA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		4 / 7 PHE A 235
VAL A 104
PHE A 256
THR A  92
 None
 0.99A 4ejjB-5uxvA:
undetectable		 4ejjB-5uxvA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		4 / 6 LEU A 189
LEU A 236
VAL A 237
PHE A 217
 None
 0.97A 4uswA-5uxvA:
undetectable		 4uswA-5uxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		5 / 8 ALA A 190
VAL A 215
PHE A 217
GLY A 200
ALA A 203
 None
 1.07A 4zjzA-5uxvA:
4.7		 4zjzA-5uxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN
(Bartonella
quintana) 		3 / 3 VAL A 237
GLU A 148
GLU A 146
 None
 0.85A 5jsdB-5uxvA:
undetectable
5jsdC-5uxvA:
undetectable		 5jsdB-5uxvA:
8.79
5jsdC-5uxvA:
8.79