SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 10 LEU A 439
VAL A 429
GLU A 328
LEU A 330
VAL A 355
 None
 0.89A 1cqpA-5uyrA:
undetectable
1cqpB-5uyrA:
undetectable		 1cqpA-5uyrA:
17.09
1cqpB-5uyrA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRE_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 12 ALA A 337
PHE A 334
SER A 370
ILE A 363
LEU A 439
 None
 1.25A 1dreA-5uyrA:
undetectable		 1dreA-5uyrA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 8 ASP A 163
VAL A 165
HIS A 283
GLY A 161
 None
 0.90A 1ekjA-5uyrA:
undetectable
1ekjB-5uyrA:
undetectable		 1ekjA-5uyrA:
undetectable
1ekjB-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 12 SER A 198
TYR A 255
LEU A 193
MET A 166
TYR A 190
 None
BLA  A 900 (-3.7A)
None
BLA  A 900 (-3.4A)
BLA  A 900 (-4.4A)
 1.45A 1p33A-5uyrA:
undetectable		 1p33A-5uyrA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 7 TYR A 221
THR A 289
GLU A 118
VAL A 248
 None
None
None
BLA  A 900 (-4.0A)
 0.95A 1tv8A-5uyrA:
undetectable		 1tv8A-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 6 LEU A 431
GLY A 402
ILE A 427
HIS A 405
 None
 0.92A 1yajF-5uyrA:
undetectable		 1yajF-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		3 / 3 SER A 496
GLU A 328
ASP A 333
 None
 0.85A 2avdB-5uyrA:
undetectable		 2avdB-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 8 TYR A 221
THR A 289
GLU A 118
VAL A 248
 None
None
None
BLA  A 900 (-4.0A)
 0.95A 2fb2A-5uyrA:
undetectable		 2fb2A-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 7 TYR A 221
THR A 289
GLU A 118
VAL A 248
 None
None
None
BLA  A 900 (-4.0A)
 0.88A 2fb2B-5uyrA:
undetectable		 2fb2B-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R6V_A_NCAA174_0
(UNCHARACTERIZED
PROTEIN PH0856)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 6 HIS A 493
ASP A 407
TRP A 489
ARG A 487
 None
 1.42A 2r6vA-5uyrA:
undetectable		 2r6vA-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 6 LEU A 416
GLU A 415
PRO A 414
ARG A 383
 None
 1.13A 3ltwA-5uyrA:
undetectable		 3ltwA-5uyrA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 10 ALA A 586
ARG A 591
GLY A 590
LEU A 613
ILE A 533
 None
 1.09A 3wdmB-5uyrA:
undetectable		 3wdmB-5uyrA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 8 ARG A 214
VAL A 248
SER A 249
HIS A 252
 BLA  A 900 (-3.0A)
BLA  A 900 (-4.0A)
BLA  A 900 (-4.3A)
BLA  A 900 (-3.6A)
 0.89A 4qknA-5uyrA:
2.5		 4qknA-5uyrA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 12 ILE A 409
GLY A 425
ALA A 358
VAL A 406
HIS A 405
 None
 1.13A 4rvdA-5uyrA:
undetectable		 4rvdA-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 12 ILE A 409
GLY A 425
ALA A 358
VAL A 406
HIS A 405
 None
 1.12A 4rvgA-5uyrA:
undetectable		 4rvgA-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 6 PHE A 516
SER A 522
ALA A 521
LEU A 518
 None
 1.15A 5dzkB-5uyrA:
undetectable
5dzkP-5uyrA:
undetectable		 5dzkB-5uyrA:
undetectable
5dzkP-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 7 PHE A 516
SER A 522
ALA A 521
LEU A 518
 None
 1.06A 5dzkD-5uyrA:
undetectable
5dzkR-5uyrA:
undetectable		 5dzkD-5uyrA:
undetectable
5dzkR-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 6 ALA A 263
THR A 262
VAL A 219
HIS A 283
 None
 1.02A 5eckA-5uyrA:
undetectable		 5eckA-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		4 / 6 ALA A 263
THR A 262
VAL A 219
HIS A 283
 None
 0.97A 5eclA-5uyrA:
undetectable		 5eclA-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 10 VAL A 355
ASP A 354
HIS A 493
LEU A 494
GLY A 360
 None
 1.20A 5m5cE-5uyrA:
undetectable		 5m5cE-5uyrA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5uyr BACTERIOPHYTOCHROME
(Xanthomonas
campestris) 		5 / 10 LEU A 187
TYR A 190
ILE A 178
LEU A 256
GLU A 186
 None
BLA  A 900 (-4.4A)
None
None
None
 1.23A 5y7pG-5uyrA:
undetectable		 5y7pG-5uyrA:
undetectable