SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uz4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_A_SAMA6735_1 (16S RRNA METHYLASE)	5uz4	SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA (Escherichia coli)	3 / 3	ASP Z 77 GLU Z 102 SER Z 267	None None G A1494 ( 4.5A)	0.82A	3p2kA-5uz4Z: 2.5	3p2kA-5uz4Z: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHD_E_EDTE301_0 (BETA-2-MICROGLOBULIN TCRBETA CHAIN)	5uz4	SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA (Escherichia coli)	4 / 8	SER Z 105 THR Z 104 ARG Z 208 ILE Z 209	None	1.09A	5jhdE-5uz4Z: undetectable 5jhdG-5uz4Z: undetectable	5jhdE-5uz4Z: 20.00 5jhdG-5uz4Z: 14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC901_0 (MRNA CAPPING ENZYME P5)	5uz4	SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA (Escherichia coli)	5 / 11	VAL Z 270 GLY Z 269 GLU Z 272 ALA Z 213 SER Z 267	None G A1494 ( 2.2A) GGM Z 402 ( 4.2A) None G A1494 ( 4.5A)	1.04A	5x6yC-5uz4Z: undetectable	5x6yC-5uz4Z: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC901_0 (MRNA CAPPING ENZYME P5)	5uz4	SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA (Escherichia coli)	5 / 11	VAL Z 270 GLY Z 269 GLU Z 272 SER Z 216 ALA Z 213	None G A1494 ( 2.2A) GGM Z 402 ( 4.2A) None None	1.07A	5x6yC-5uz4Z: undetectable	5x6yC-5uz4Z: 19.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3P2K_A_SAMA6735_1","16S RRNA METHYLASE","5uz4","SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA","Escherichia coli",3,"ASP Z  77;GLU Z 102;SER Z 267","None;None;  G A1494 ( 4.5A)","0.82A","3p2kA-5uz4Z:2.5","3p2kA-5uz4Z:21.10"],["5JHD_E_EDTE301_0","BETA-2-MICROGLOBULIN;TCRBETA CHAIN","5uz4","SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA","Escherichia coli",4,"SER Z 105;THR Z 104;ARG Z 208;ILE Z 209","None","1.09A","5jhdE-5uz4Z:undetectable;5jhdG-5uz4Z:undetectable","5jhdE-5uz4Z:20.00;5jhdG-5uz4Z:14.20"],["5X6Y_C_SAMC901_0","MRNA CAPPING ENZYME P5","5uz4","SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA","Escherichia coli",5,"VAL Z 270;GLY Z 269;GLU Z 272;ALA Z 213;SER Z 267","None;  G A1494 ( 2.2A);GGM Z 402 ( 4.2A);None;  G A1494 ( 4.5A)","1.04A","5x6yC-5uz4Z:undetectable","5x6yC-5uz4Z:19.76"],["5X6Y_C_SAMC901_0","MRNA CAPPING ENZYME P5","5uz4","SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA","Escherichia coli",5,"VAL Z 270;GLY Z 269;GLU Z 272;SER Z 216;ALA Z 213","None;  G A1494 ( 2.2A);GGM Z 402 ( 4.2A);None;None","1.07A","5x6yC-5uz4Z:undetectable","5x6yC-5uz4Z:19.76"]]