SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5v0s PREPHENATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 LEU A 320
GLY A 345
ILE A 339
LEU A 367
THR A 374
 None
 0.99A 1p91B-5v0sA:
undetectable		 1p91B-5v0sA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 5v0s PREPHENATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 LEU A 367
ALA A 319
ASP A 315
GLY A 348
THR A 374
 None
 1.01A 3spkA-5v0sA:
undetectable		 3spkA-5v0sA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5v0s PREPHENATE
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 LEU A 367
ALA A 319
ASP A 315
GLY A 348
THR A 374
 None
 1.00A 3spkB-5v0sA:
undetectable		 3spkB-5v0sA:
21.36