SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 SER A 387
VAL A 386
MET A 445
LEU A 409
VAL A 371
 None
 1.44A 1a27A-5v0tA:
7.8		 1a27A-5v0tA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 HIS A 139
ILE A 239
LEU A 409
ASP A 376
GLY A 377
 None
None
None
UDP  A 501 ( 4.5A)
None
 1.14A 1axwA-5v0tA:
undetectable		 1axwA-5v0tA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 ARG A 151
ALA A 147
ASP A 190
GLY A 160
 None
 1.12A 1e7bA-5v0tA:
undetectable		 1e7bA-5v0tA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 GLU A 296
ILE A 335
ARG A 293
ALA A 424
ARG A 338
 None
 1.11A 1ki7B-5v0tA:
undetectable		 1ki7B-5v0tA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 GLY A 283
GLU A 286
LEU A 278
ILE A 324
HIS A  99
 None
FMT  A 512 (-3.7A)
None
None
None
 1.13A 1kyvA-5v0tA:
4.4
1kyvE-5v0tA:
4.2		 1kyvA-5v0tA:
16.40
1kyvE-5v0tA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 HIS A  99
GLY A 283
GLU A 286
LEU A 278
ILE A 324
 None
None
FMT  A 512 (-3.7A)
None
None
 1.13A 1kyvB-5v0tA:
4.3
1kyvC-5v0tA:
4.4		 1kyvB-5v0tA:
16.40
1kyvC-5v0tA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 HIS A  99
GLY A 283
GLU A 286
LEU A 278
ILE A 324
 None
None
FMT  A 512 (-3.7A)
None
None
 1.16A 1kyvC-5v0tA:
4.3
1kyvD-5v0tA:
4.4		 1kyvC-5v0tA:
16.40
1kyvD-5v0tA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 HIS A  99
GLY A 283
GLU A 286
LEU A 278
ILE A 324
 None
None
FMT  A 512 (-3.7A)
None
None
 1.16A 1kyvD-5v0tA:
4.4
1kyvE-5v0tA:
4.3		 1kyvD-5v0tA:
16.40
1kyvE-5v0tA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 PHE A 363
GLU A 384
ARG A 356
HIS A 442
PRO A 243
 None
UDP  A 501 (-2.8A)
None
None
FMT  A 509 ( 4.6A)
 1.29A 1mj2C-5v0tA:
undetectable
1mj2D-5v0tA:
undetectable		 1mj2C-5v0tA:
11.56
1mj2D-5v0tA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 8 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.88A 1v54C-5v0tA:
undetectable
1v54J-5v0tA:
undetectable		 1v54C-5v0tA:
20.08
1v54J-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 8 LEU A  40
HIS A 139
HIS A 164
ALA A  39
 None
 0.97A 2bnnA-5v0tA:
undetectable
2bnnB-5v0tA:
undetectable		 2bnnA-5v0tA:
19.34
2bnnB-5v0tA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 8 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.88A 2dyrC-5v0tA:
undetectable
2dyrJ-5v0tA:
undetectable		 2dyrC-5v0tA:
20.08
2dyrJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.87A 2eikC-5v0tA:
undetectable
2eikJ-5v0tA:
undetectable		 2eikC-5v0tA:
20.08
2eikJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 8 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.88A 2eilC-5v0tA:
undetectable
2eilJ-5v0tA:
undetectable		 2eilC-5v0tA:
20.08
2eilJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 LEU A 294
SER A 298
VAL A 368
HIS A 367
LEU A 266
 None
None
None
ACT  A 505 ( 4.2A)
EDO  A 503 ( 4.7A)
 1.33A 2hc4A-5v0tA:
undetectable		 2hc4A-5v0tA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 ASN A  17
ARG A  18
ASP A 317
 None
G6P  A 502 (-3.8A)
None
 0.98A 2qe6A-5v0tA:
undetectable		 2qe6A-5v0tA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 ASN A  17
ARG A  18
ASP A 317
 None
G6P  A 502 (-3.8A)
None
 0.94A 2qe6B-5v0tA:
undetectable		 2qe6B-5v0tA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 VAL A 138
ASN A 119
TRP A 116
 None
 0.87A 2y00B-5v0tA:
undetectable		 2y00B-5v0tA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.96A 2y69C-5v0tA:
undetectable
2y69J-5v0tA:
undetectable		 2y69C-5v0tA:
20.08
2y69J-5v0tA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 1.04A 2y69P-5v0tA:
undetectable
2y69W-5v0tA:
undetectable		 2y69P-5v0tA:
20.08
2y69W-5v0tA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.90A 3abkP-5v0tA:
undetectable
3abkW-5v0tA:
undetectable		 3abkP-5v0tA:
20.08
3abkW-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.94A 3abmC-5v0tA:
undetectable
3abmJ-5v0tA:
undetectable		 3abmC-5v0tA:
20.08
3abmJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.97A 3abmP-5v0tA:
undetectable
3abmW-5v0tA:
undetectable		 3abmP-5v0tA:
20.08
3abmW-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.96A 3ag3C-5v0tA:
undetectable
3ag3J-5v0tA:
undetectable		 3ag3C-5v0tA:
20.08
3ag3J-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 8 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.89A 3ag4C-5v0tA:
undetectable
3ag4J-5v0tA:
undetectable		 3ag4C-5v0tA:
20.08
3ag4J-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.86A 3asnC-5v0tA:
undetectable
3asnJ-5v0tA:
undetectable		 3asnC-5v0tA:
20.08
3asnJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 8 LEU A 397
THR A 372
ALA A 405
ALA A 403
 None
 1.01A 3ax9B-5v0tA:
undetectable		 3ax9B-5v0tA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 ILE A  14
HIS A 139
ARG A 458
GLY A  35
 None
None
ACT  A 506 (-4.3A)
None
 1.22A 3b9mA-5v0tA:
undetectable		 3b9mA-5v0tA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.84A 3wg7C-5v0tA:
undetectable
3wg7J-5v0tA:
undetectable		 3wg7C-5v0tA:
20.08
3wg7J-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.87A 3x2qC-5v0tA:
undetectable
3x2qJ-5v0tA:
undetectable		 3x2qC-5v0tA:
20.08
3x2qJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 139
ILE A 239
LEU A 409
ASP A 376
GLY A 377
 None
None
None
UDP  A 501 ( 4.5A)
None
 1.13A 4fogA-5v0tA:
undetectable		 4fogA-5v0tA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 139
ILE A 239
LEU A 409
ASP A 376
GLY A 377
 None
None
None
UDP  A 501 ( 4.5A)
None
 0.99A 4fogC-5v0tA:
undetectable		 4fogC-5v0tA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.74A 4k8cA-5v0tA:
3.9		 4k8cA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.91A 4k8cA-5v0tA:
3.9		 4k8cA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.73A 4kahA-5v0tA:
3.9		 4kahA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.92A 4kahA-5v0tA:
3.9		 4kahA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.72A 4kahB-5v0tA:
4.4		 4kahB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.91A 4kahB-5v0tA:
4.4		 4kahB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.76A 4kanA-5v0tA:
3.4		 4kanA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.91A 4kanA-5v0tA:
3.4		 4kanA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.74A 4kanB-5v0tA:
5.0		 4kanB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.91A 4kanB-5v0tA:
5.0		 4kanB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.73A 4kbeA-5v0tA:
4.3		 4kbeA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.91A 4kbeA-5v0tA:
4.3		 4kbeA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.73A 4kbeB-5v0tA:
5.2		 4kbeB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.88A 4kbeB-5v0tA:
5.2		 4kbeB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 ARG A 458
GLY A  35
ASP A  38
GLY A 240
 ACT  A 506 (-4.3A)
None
None
None
 0.89A 4koeA-5v0tA:
undetectable
4koeB-5v0tA:
undetectable
4koeC-5v0tA:
2.8		 4koeA-5v0tA:
21.74
4koeB-5v0tA:
21.74
4koeC-5v0tA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 ARG A 458
GLY A  35
ASP A  38
GLY A 240
 ACT  A 506 (-4.3A)
None
None
None
 0.87A 4koeA-5v0tA:
undetectable
4koeB-5v0tA:
undetectable
4koeD-5v0tA:
3.2		 4koeA-5v0tA:
21.74
4koeB-5v0tA:
21.74
4koeD-5v0tA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.73A 4lbgA-5v0tA:
3.4		 4lbgA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.94A 4lbgA-5v0tA:
3.4		 4lbgA-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A  90
TYR A 115
PRO A  96
 None
 0.73A 4lbgB-5v0tA:
4.3		 4lbgB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		3 / 3 SER A 281
TYR A 280
PRO A 166
 None
 0.93A 4lbgB-5v0tA:
4.3		 4lbgB-5v0tA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 ASP A 376
ARG A 277
SER A 281
HIS A  99
 UDP  A 501 ( 4.5A)
UDP  A 501 ( 3.9A)
None
None
 1.46A 4o4dA-5v0tA:
undetectable		 4o4dA-5v0tA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 11 GLY A 377
PHE A 167
TYR A 206
ASP A 199
PRO A 168
 None
 1.24A 4rtrA-5v0tA:
2.0		 4rtrA-5v0tA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 GLY A 377
PHE A 167
TYR A 206
ASP A 199
PRO A 168
 None
 1.26A 4rtsA-5v0tA:
undetectable		 4rtsA-5v0tA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 ILE A 165
SER A  90
HIS A 142
ASP A 279
 G6P  A 502 (-4.8A)
None
G6P  A 502 (-4.7A)
None
 1.27A 4rzvB-5v0tA:
undetectable		 4rzvB-5v0tA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PRO A 168
PHE A  98
TRP A  95
TYR A 280
 None
 1.44A 4v2yA-5v0tA:
undetectable		 4v2yA-5v0tA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 ILE A 310
VAL A 358
PHE A 363
THR A 365
 None
None
None
FMT  A 510 ( 4.8A)
 1.07A 4xe5A-5v0tA:
undetectable		 4xe5A-5v0tA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 GLY A  35
ASP A  38
GLY A 240
ARG A 458
 None
None
None
ACT  A 506 (-4.3A)
 0.92A 4z53A-5v0tA:
undetectable
4z53B-5v0tA:
undetectable		 4z53A-5v0tA:
20.58
4z53B-5v0tA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 ARG A 458
GLY A  35
ASP A  38
GLY A 240
 ACT  A 506 (-4.3A)
None
None
None
 0.87A 4z53A-5v0tA:
undetectable
4z53B-5v0tA:
undetectable		 4z53A-5v0tA:
20.58
4z53B-5v0tA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PRO A 168
PHE A  98
TRP A  95
TYR A 280
 None
 1.46A 5amkB-5v0tA:
undetectable		 5amkB-5v0tA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.95A 5b1bC-5v0tA:
undetectable
5b1bJ-5v0tA:
undetectable		 5b1bC-5v0tA:
20.08
5b1bJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.90A 5b1bP-5v0tA:
undetectable
5b1bW-5v0tA:
undetectable		 5b1bP-5v0tA:
20.08
5b1bW-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PHE A 291
ARG A 338
ILE A 335
GLY A 337
 None
 0.96A 5nzyA-5v0tA:
undetectable		 5nzyA-5v0tA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 PRO A 168
PHE A  98
TRP A  95
TYR A 280
 None
 1.43A 5oh1A-5v0tA:
undetectable		 5oh1A-5v0tA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.92A 5wauC-5v0tA:
undetectable
5wauJ-5v0tA:
undetectable		 5wauC-5v0tA:
20.08
5wauJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.89A 5wauc-5v0tA:
undetectable
5wauj-5v0tA:
undetectable		 5wauc-5v0tA:
20.08
5wauj-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.94A 5xdqC-5v0tA:
undetectable
5xdqJ-5v0tA:
undetectable		 5xdqC-5v0tA:
20.08
5xdqJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 5 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.91A 5xdqP-5v0tA:
undetectable
5xdqW-5v0tA:
undetectable		 5xdqP-5v0tA:
20.08
5xdqW-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.94A 5z84P-5v0tA:
undetectable
5z84W-5v0tA:
undetectable		 5z84P-5v0tA:
20.08
5z84W-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.93A 5z85P-5v0tA:
undetectable
5z85W-5v0tA:
undetectable		 5z85P-5v0tA:
20.08
5z85W-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.93A 5z86C-5v0tA:
undetectable
5z86J-5v0tA:
undetectable		 5z86C-5v0tA:
20.08
5z86J-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.94A 5z86P-5v0tA:
undetectable
5z86W-5v0tA:
undetectable		 5z86P-5v0tA:
20.08
5z86W-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.93A 5zcoP-5v0tA:
undetectable
5zcoW-5v0tA:
undetectable		 5zcoP-5v0tA:
20.08
5zcoW-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.91A 5zcpC-5v0tA:
undetectable
5zcpJ-5v0tA:
undetectable		 5zcpC-5v0tA:
20.08
5zcpJ-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 167
PHE A  98
LEU A  94
PHE A  89
 None
 0.96A 5zcpP-5v0tA:
undetectable
5zcpW-5v0tA:
undetectable		 5zcpP-5v0tA:
20.08
5zcpW-5v0tA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 ASP A 140
HIS A  99
ASN A  91
HIS A 142
PHE A 161
 G6P  A 502 (-3.3A)
None
G6P  A 502 ( 4.6A)
G6P  A 502 (-4.7A)
None
 1.50A 6exiD-5v0tA:
3.2		 6exiD-5v0tA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 GLY A  30
GLY A  31
LEU A  32
HIS A 142
ARG A 277
 UDP  A 501 (-3.4A)
UDP  A 501 ( 3.1A)
G6P  A 502 (-3.9A)
G6P  A 502 (-4.7A)
UDP  A 501 ( 3.9A)
 0.88A 6gngB-5v0tA:
21.9		 6gngB-5v0tA:
25.08