SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
5v10 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa)
4 / 4 LEU A  80
VAL A 100
CYH A 110
ALA A  68
None
1.08A 1mz9E-5v10A:
undetectable
1mz9E-5v10A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)
5v10 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa)
4 / 8 ASP A  20
PHE A  35
LEU A  80
ASP A  78
None
0.99A 1rmtD-5v10A:
undetectable
1rmtD-5v10A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)
5v10 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa)
4 / 7 TYR A  32
THR A  21
LEU A  80
VAL A  16
None
1.05A 2cppA-5v10A:
undetectable
2cppA-5v10A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)
5v10 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa)
4 / 6 PHE A  49
LEU A  44
ALA A 136
GLN A  51
None
1.09A 6b89B-5v10A:
undetectable
6b89B-5v10A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5v10 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa)
4 / 6 LEU A  59
ASP A  57
ARG A 127
GLN A  53
None
1.11A 6g31J-5v10A:
undetectable
6g31J-5v10A:
23.68