SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		4 / 8 PHE B 172
PHE B 169
GLU B  27
GLN B  28
 None
 1.44A 2aoxA-5v13B:
undetectable		 2aoxA-5v13B:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_B_THAB401_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		4 / 7 PHE B 172
PHE B 169
GLU B  27
GLN B  28
 None
 1.44A 2aoxB-5v13B:
undetectable		 2aoxB-5v13B:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		4 / 8 SER B  40
GLN B  62
TRP B  50
LYS B  47
 None
 1.13A 2cmlB-5v13B:
undetectable		 2cmlB-5v13B:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		4 / 8 SER B  40
GLN B  62
TRP B  50
LYS B  47
 None
 1.08A 2cmlD-5v13B:
undetectable		 2cmlD-5v13B:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		5 / 11 ALA B 256
LYS B 223
ILE B 258
SER B 253
LEU B 254
 None
 1.12A 3gyqB-5v13B:
undetectable		 3gyqB-5v13B:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		5 / 12 LEU B  74
PHE B 132
LEU B 102
LEU B 105
ALA B  97
 None
 1.17A 3vw7A-5v13B:
undetectable		 3vw7A-5v13B:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5v13 AAEL008620-PA
ODORANT-BINDING
PROTEIN
(Aedes
aegypti) 		3 / 3 TYR B  33
HIS B 145
MET B 143
 JH3  B 301 (-3.8A)
None
None
 1.12A 6af6A-5v13B:
undetectable		 6af6A-5v13B:
20.05