SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.15A 1dz4B-5v1mA:
undetectable		 1dz4B-5v1mA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 5 GLU A  93
LEU A  99
LEU A  96
LEU A  98
 None
 0.98A 1np1A-5v1mA:
undetectable		 1np1A-5v1mA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 5 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.14A 1t88B-5v1mA:
undetectable		 1t88B-5v1mA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 8 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.08A 1uyuB-5v1mA:
undetectable		 1uyuB-5v1mA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 5 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.17A 2m56A-5v1mA:
undetectable		 2m56A-5v1mA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 LEU A 123
MET A 145
THR A 146
LEU A 264
 None
None
GOL  A 305 ( 2.9A)
None
 1.09A 2zxwA-5v1mA:
undetectable
2zxwJ-5v1mA:
undetectable		 2zxwA-5v1mA:
16.50
2zxwJ-5v1mA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.11A 3fwgA-5v1mA:
undetectable		 3fwgA-5v1mA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 137
HIS A  84
THR A  83
VAL A 127
 None
GOL  A 303 (-3.4A)
None
None
 0.80A 3lb3A-5v1mA:
undetectable		 3lb3A-5v1mA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 137
HIS A  84
THR A  83
VAL A 127
 None
GOL  A 303 (-3.4A)
None
None
 0.72A 3lb3B-5v1mA:
undetectable		 3lb3B-5v1mA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.09A 3wrhE-5v1mA:
undetectable		 3wrhE-5v1mA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.10A 3wrjE-5v1mA:
undetectable		 3wrjE-5v1mA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 8 ASP A 217
GLY A 216
VAL A 110
CYH A 214
 None
None
CL  A 301 ( 4.4A)
None
 0.88A 4c5nC-5v1mA:
undetectable		 4c5nC-5v1mA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.09A 4ek1A-5v1mA:
undetectable		 4ek1A-5v1mA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.14A 4g3rA-5v1mA:
undetectable		 4g3rA-5v1mA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 5 VAL A 189
ARG A 144
MET A 193
GLU A 195
 None
GOL  A 304 (-3.7A)
None
GOL  A 304 (-2.2A)
 1.41A 4hojA-5v1mA:
undetectable		 4hojA-5v1mA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.15A 4kkyX-5v1mA:
undetectable		 4kkyX-5v1mA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 5 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.16A 4l49A-5v1mA:
undetectable		 4l49A-5v1mA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 8 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.12A 4l4dA-5v1mA:
undetectable		 4l4dA-5v1mA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 8 PHE A 151
LEU A 123
VAL A  87
VAL A 175
 None
 1.10A 4l4fA-5v1mA:
undetectable		 4l4fA-5v1mA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 12 ILE A 160
GLN A 231
VAL A 101
LEU A 243
LEU A 173
 None
 1.20A 4qztA-5v1mA:
undetectable		 4qztA-5v1mA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		3 / 3 CYH A 253
LYS A 254
HIS A  84
 None
GOL  A 303 (-3.5A)
GOL  A 303 (-3.4A)
 1.12A 5js5A-5v1mA:
undetectable		 5js5A-5v1mA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v1m U6 SNRNA
PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 LEU A 123
MET A 145
THR A 146
LEU A 264
 None
None
GOL  A 305 ( 2.9A)
None
 1.09A 5x1fA-5v1mA:
undetectable
5x1fJ-5v1mA:
undetectable		 5x1fA-5v1mA:
16.50
5x1fJ-5v1mA:
14.66