SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v1w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 ALA A 307
VAL A 178
TRP A 159
 None
 0.93A 1c4dA-5v1wA:
undetectable
1c4dB-5v1wA:
undetectable		 1c4dA-5v1wA:
2.37
1c4dB-5v1wA:
2.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 TRP A 159
ALA A 307
VAL A 178
 None
 0.77A 1c4dA-5v1wA:
undetectable
1c4dB-5v1wA:
undetectable		 1c4dA-5v1wA:
2.37
1c4dB-5v1wA:
2.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 4 HIS A 549
VAL A 554
ASN A 553
THR A 552
 None
 1.26A 1dy5A-5v1wA:
undetectable		 1dy5A-5v1wA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 9 LEU A 373
ALA A 400
LEU A 411
LEU A 396
ALA A 376
 None
 1.40A 1sn0A-5v1wA:
undetectable
1sn0C-5v1wA:
undetectable		 1sn0A-5v1wA:
10.81
1sn0C-5v1wA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 TYR A 111
ASP A 112
HIS A 120
HIS A 131
GLY A 132
 None
None
EDO  A 814 (-4.0A)
EDO  A 814 (-4.3A)
None
 1.48A 1t69A-5v1wA:
undetectable		 1t69A-5v1wA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 ARG A 509
LEU A 573
LEU A 517
TRP A 276
 None
 1.03A 1ukbA-5v1wA:
undetectable		 1ukbA-5v1wA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 PHE A 773
LEU A 355
VAL A 354
VAL A 724
HIS A 640
 None
None
None
None
PO4  A 806 (-3.8A)
 1.29A 2hc4A-5v1wA:
undetectable		 2hc4A-5v1wA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 9 ALA A 265
ALA A 248
PHE A 212
GLY A 211
ALA A 222
 None
 1.39A 2vh3A-5v1wA:
1.2		 2vh3A-5v1wA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 ASN A  92
GLY A 135
ILE A 183
TYR A 176
 None
 0.97A 2yoeB-5v1wA:
2.2
2yoeC-5v1wA:
2.2		 2yoeB-5v1wA:
17.29
2yoeC-5v1wA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_C_GLYC73_0
(NONSTRUCTURAL
PROTEIN 1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 4 ASP A 530
ASP A 466
SER A 459
ARG A 463
 BGC  A 801 (-3.5A)
BGC  A 801 ( 2.7A)
BGC  A 802 ( 4.6A)
BGC  A 802 (-3.5A)
 1.40A 2z0aC-5v1wA:
3.5		 2z0aC-5v1wA:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 HIS A 716
ASP A 363
GLU A 720
LYS A 740
LEU A 681
 PO4  A 812 (-3.8A)
None
None
None
None
 1.47A 3g1uC-5v1wA:
undetectable		 3g1uC-5v1wA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 GLU A 480
HIS A 713
PHE A 773
PRO A 356
LEU A 355
 None
EDO  A 820 (-3.8A)
None
None
None
 1.20A 3j6pB-5v1wA:
undetectable		 3j6pB-5v1wA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 GLU A 480
PHE A 773
PRO A 356
GLY A 633
LEU A 355
 None
 1.10A 3j6pB-5v1wA:
undetectable		 3j6pB-5v1wA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 9 PHE A  98
GLY A 177
PRO A  95
ILE A 140
PHE A 110
 None
 0.98A 3ko0H-5v1wA:
undetectable
3ko0I-5v1wA:
undetectable		 3ko0H-5v1wA:
9.53
3ko0I-5v1wA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 THR A 286
THR A 287
THR A 288
ALA A 317
SER A 319
 EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
None
 1.01A 3mg02-5v1wA:
undetectable
3mg0V-5v1wA:
undetectable		 3mg02-5v1wA:
14.20
3mg0V-5v1wA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 TYR A 671
PHE A 674
VAL A 645
ILE A 581
 None
 0.96A 3n9jA-5v1wA:
2.4		 3n9jA-5v1wA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 TRP A 606
ASP A 611
ILE A 604
TRP A 615
HIS A 129
 None
None
None
BGC  A 801 (-3.8A)
EDO  A 814 (-4.3A)
 1.27A 3pocA-5v1wA:
undetectable		 3pocA-5v1wA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 ASP A 678
GLY A 722
GLY A 362
ASP A 363
PHE A 738
 None
 1.14A 3prsA-5v1wA:
undetectable		 3prsA-5v1wA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 PHE A 738
PHE A 674
ALA A 673
LEU A 358
 None
None
None
EDO  A 820 (-4.2A)
 0.99A 3t3zA-5v1wA:
undetectable		 3t3zA-5v1wA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 PHE A 738
PHE A 674
ALA A 673
LEU A 358
 None
None
None
EDO  A 820 (-4.2A)
 0.97A 3t3zB-5v1wA:
undetectable		 3t3zB-5v1wA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 5 PHE A 738
PHE A 674
ALA A 673
LEU A 358
 None
None
None
EDO  A 820 (-4.2A)
 0.94A 3t3zC-5v1wA:
undetectable		 3t3zC-5v1wA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 PHE A 738
PHE A 674
ALA A 673
LEU A 358
 None
None
None
EDO  A 820 (-4.2A)
 0.96A 3t3zD-5v1wA:
undetectable		 3t3zD-5v1wA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 5 HIS A 315
SER A 579
THR A 576
ASP A 725
 PO4  A 808 (-3.8A)
PO4  A 808 (-4.9A)
None
None
 1.02A 3tm4A-5v1wA:
undetectable		 3tm4A-5v1wA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 5 HIS A 315
SER A 579
THR A 576
ASP A 725
 PO4  A 808 (-3.8A)
PO4  A 808 (-4.9A)
None
None
 1.05A 3tm4B-5v1wA:
undetectable		 3tm4B-5v1wA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 7 THR A 214
HIS A 115
ASN A 116
TYR A 220
 None
EDO  A 816 (-3.7A)
None
None
 1.27A 4a3uA-5v1wA:
undetectable		 4a3uA-5v1wA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 7 THR A 214
HIS A 115
ASN A 116
TYR A 220
 None
EDO  A 816 (-3.7A)
None
None
 1.24A 4a3uB-5v1wA:
undetectable		 4a3uB-5v1wA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 ASN A 440
TRP A 426
ASP A  45
 None
 0.92A 4a7tA-5v1wA:
undetectable
4a7tF-5v1wA:
undetectable		 4a7tA-5v1wA:
11.82
4a7tF-5v1wA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 ASN A 540
TRP A 606
ASP A 466
 BGC  A 801 (-3.1A)
None
BGC  A 801 ( 2.7A)
 1.10A 4a7tA-5v1wA:
undetectable
4a7tF-5v1wA:
undetectable		 4a7tA-5v1wA:
11.82
4a7tF-5v1wA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 GLN A  58
GLY A 453
ALA A 456
ARG A 518
ILE A 451
 None
 1.24A 4azsA-5v1wA:
undetectable		 4azsA-5v1wA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 GLN A  58
GLY A 453
ALA A 456
ARG A 518
ILE A 451
 None
 1.17A 4azwA-5v1wA:
undetectable		 4azwA-5v1wA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 PRO A 630
ILE A 626
TYR A 473
TYR A 387
 None
None
None
EDO  A 819 ( 3.5A)
 1.23A 4g10A-5v1wA:
undetectable		 4g10A-5v1wA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 5 GLU A 480
ARG A 416
PRO A 401
SER A 357
 None
None
None
EDO  A 820 (-4.0A)
 1.35A 4k17B-5v1wA:
undetectable		 4k17B-5v1wA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 ARG A 162
ARG A 270
ASP A 243
GLU A 188
 EDO  A 821 ( 4.7A)
None
None
EDO  A 821 (-4.7A)
 1.16A 4kr4C-5v1wA:
undetectable		 4kr4C-5v1wA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 PHE A 306
THR A 304
VAL A 269
PHE A 184
 None
None
EDO  A 815 (-4.4A)
None
 1.03A 4ltwA-5v1wA:
undetectable		 4ltwA-5v1wA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 ASN A 116
ASP A 216
ASP A 197
 None
 0.74A 4obwD-5v1wA:
undetectable		 4obwD-5v1wA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.96A 4qvlV-5v1wA:
undetectable
4qvlb-5v1wA:
undetectable		 4qvlV-5v1wA:
15.01
4qvlb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.96A 4qvlH-5v1wA:
undetectable
4qvlN-5v1wA:
undetectable		 4qvlH-5v1wA:
15.01
4qvlN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 4qvmV-5v1wA:
undetectable
4qvmb-5v1wA:
undetectable		 4qvmV-5v1wA:
15.01
4qvmb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 4qvmH-5v1wA:
undetectable
4qvmN-5v1wA:
undetectable		 4qvmH-5v1wA:
15.01
4qvmN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.01A 4qvnV-5v1wA:
undetectable
4qvnb-5v1wA:
undetectable		 4qvnV-5v1wA:
15.01
4qvnb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.01A 4qvnH-5v1wA:
undetectable
4qvnN-5v1wA:
undetectable		 4qvnH-5v1wA:
15.01
4qvnN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 4qvpV-5v1wA:
undetectable
4qvpb-5v1wA:
undetectable		 4qvpV-5v1wA:
15.01
4qvpb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 4qvpH-5v1wA:
undetectable
4qvpN-5v1wA:
undetectable		 4qvpH-5v1wA:
15.01
4qvpN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 4qvqV-5v1wA:
undetectable
4qvqb-5v1wA:
undetectable		 4qvqV-5v1wA:
15.01
4qvqb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 4qvqH-5v1wA:
undetectable
4qvqN-5v1wA:
undetectable		 4qvqH-5v1wA:
15.01
4qvqN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 10 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 4qvvV-5v1wA:
undetectable
4qvvb-5v1wA:
undetectable		 4qvvV-5v1wA:
15.01
4qvvb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 10 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 4qvvH-5v1wA:
undetectable
4qvvN-5v1wA:
undetectable		 4qvvH-5v1wA:
15.01
4qvvN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.97A 4qvwV-5v1wA:
undetectable
4qvwb-5v1wA:
undetectable		 4qvwV-5v1wA:
15.01
4qvwb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.97A 4qvwH-5v1wA:
undetectable
4qvwN-5v1wA:
undetectable		 4qvwH-5v1wA:
15.01
4qvwN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.94A 4qvyV-5v1wA:
undetectable
4qvyb-5v1wA:
1.6		 4qvyV-5v1wA:
15.01
4qvyb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.94A 4qvyH-5v1wA:
undetectable
4qvyN-5v1wA:
undetectable		 4qvyH-5v1wA:
15.01
4qvyN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.97A 4qw0V-5v1wA:
undetectable
4qw0b-5v1wA:
undetectable		 4qw0V-5v1wA:
15.01
4qw0b-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.96A 4qw0H-5v1wA:
undetectable
4qw0N-5v1wA:
undetectable		 4qw0H-5v1wA:
15.01
4qw0N-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.97A 4qw1V-5v1wA:
undetectable
4qw1b-5v1wA:
undetectable		 4qw1V-5v1wA:
15.01
4qw1b-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 4qw1H-5v1wA:
undetectable
4qw1N-5v1wA:
undetectable		 4qw1H-5v1wA:
15.01
4qw1N-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 4qw3V-5v1wA:
undetectable
4qw3b-5v1wA:
undetectable		 4qw3V-5v1wA:
15.01
4qw3b-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 4qw3H-5v1wA:
undetectable
4qw3N-5v1wA:
undetectable		 4qw3H-5v1wA:
15.01
4qw3N-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 TYR A 574
GLY A 353
PRO A 352
 None
 0.66A 4qwpA-5v1wA:
undetectable		 4qwpA-5v1wA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 4qwuV-5v1wA:
undetectable
4qwub-5v1wA:
undetectable		 4qwuV-5v1wA:
15.01
4qwub-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 4qwuH-5v1wA:
undetectable
4qwuN-5v1wA:
undetectable		 4qwuH-5v1wA:
15.01
4qwuN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 10 GLY A 106
ILE A 174
LEU A 107
LEU A 165
TYR A 176
 None
 1.15A 4xj7A-5v1wA:
undetectable
4xj7B-5v1wA:
undetectable		 4xj7A-5v1wA:
17.12
4xj7B-5v1wA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 LEU A 194
ILE A 247
ALA A 246
ALA A 242
 None
 0.68A 4zf8A-5v1wA:
undetectable		 4zf8A-5v1wA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 TYR A 176
GLY A  82
SER A  83
LEU A  84
 None
 1.20A 5bphA-5v1wA:
undetectable		 5bphA-5v1wA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 4 TYR A 176
GLY A  82
SER A  83
LEU A  84
 None
 1.20A 5bphC-5v1wA:
undetectable		 5bphC-5v1wA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 TYR A 176
GLY A  82
SER A  83
LEU A  84
 None
 1.27A 5bphD-5v1wA:
undetectable		 5bphD-5v1wA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 5bxnV-5v1wA:
undetectable
5bxnb-5v1wA:
undetectable		 5bxnV-5v1wA:
14.87
5bxnb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.01A 5bxnH-5v1wA:
undetectable
5bxnN-5v1wA:
undetectable		 5bxnH-5v1wA:
14.87
5bxnN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 9 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 5cz7V-5v1wA:
undetectable
5cz7b-5v1wA:
1.6		 5cz7V-5v1wA:
15.01
5cz7b-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.97A 5cz7H-5v1wA:
undetectable
5cz7N-5v1wA:
undetectable		 5cz7H-5v1wA:
15.01
5cz7N-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.95A 5d0xV-5v1wA:
undetectable
5d0xb-5v1wA:
undetectable		 5d0xV-5v1wA:
15.01
5d0xb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.96A 5d0xH-5v1wA:
undetectable
5d0xN-5v1wA:
undetectable		 5d0xH-5v1wA:
15.01
5d0xN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 GLY A 525
HIS A 311
ALA A 274
THR A 347
 None
 0.89A 5eevL-5v1wA:
undetectable
5eevV-5v1wA:
undetectable		 5eevL-5v1wA:
8.11
5eevV-5v1wA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 GLY A 525
HIS A 311
ALA A 274
THR A 347
 None
 0.89A 5eewL-5v1wA:
undetectable
5eewV-5v1wA:
undetectable		 5eewL-5v1wA:
8.11
5eewV-5v1wA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 GLY A 525
HIS A 311
ALA A 274
THR A 347
 None
 0.89A 5ef3L-5v1wA:
undetectable
5ef3V-5v1wA:
undetectable		 5ef3L-5v1wA:
8.11
5ef3V-5v1wA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 7 LEU A 452
THR A 450
PRO A  61
MET A 519
 None
 0.86A 5fxtA-5v1wA:
undetectable		 5fxtA-5v1wA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 5l5fV-5v1wA:
undetectable
5l5fb-5v1wA:
1.4		 5l5fV-5v1wA:
15.01
5l5fb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 5l5fH-5v1wA:
undetectable
5l5fN-5v1wA:
undetectable		 5l5fH-5v1wA:
15.01
5l5fN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.98A 5l5zV-5v1wA:
undetectable
5l5zb-5v1wA:
undetectable		 5l5zV-5v1wA:
15.01
5l5zb-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.97A 5l5zH-5v1wA:
undetectable
5l5zN-5v1wA:
undetectable		 5l5zH-5v1wA:
15.01
5l5zN-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 5l66V-5v1wA:
undetectable
5l66b-5v1wA:
undetectable		 5l66V-5v1wA:
15.01
5l66b-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 5l66H-5v1wA:
undetectable
5l66N-5v1wA:
undetectable		 5l66H-5v1wA:
15.01
5l66N-5v1wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 10 GLY A 633
GLY A 634
ASN A 553
PHE A 751
ILE A 734
 None
 1.43A 5lbtA-5v1wA:
undetectable
5lbtB-5v1wA:
undetectable		 5lbtA-5v1wA:
15.05
5lbtB-5v1wA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 SER A 318
ALA A 317
THR A 286
 None
None
EDO  A 818 (-4.2A)
 0.74A 5n0xB-5v1wA:
undetectable		 5n0xB-5v1wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 TYR A 176
SER A  99
TRP A  80
 None
 0.93A 5n8jB-5v1wA:
1.4		 5n8jB-5v1wA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 TYR A 176
SER A  99
TRP A  80
 None
 0.91A 5n8jA-5v1wA:
undetectable		 5n8jA-5v1wA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		3 / 3 TYR A 176
SER A  99
TRP A  80
 None
 0.89A 5n8jD-5v1wA:
1.5		 5n8jD-5v1wA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 TYR A 624
THR A 603
VAL A 588
TYR A 644
 None
 1.21A 5ov9B-5v1wA:
undetectable		 5ov9B-5v1wA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 7 TYR A 671
GLN A 683
ASP A 679
TYR A 644
 None
 1.25A 5ov9B-5v1wA:
undetectable		 5ov9B-5v1wA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 8 GLY A 390
GLU A 546
GLN A  58
TRP A 426
 None
EDO  A 819 (-3.2A)
None
None
 0.96A 5vlmD-5v1wA:
1.6		 5vlmD-5v1wA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 7 PHE A 415
ARG A 416
LEU A 396
ALA A 376
 None
 1.31A 6b89A-5v1wA:
undetectable		 6b89A-5v1wA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 HIS A 713
ASN A 717
SER A 357
LEU A 369
LEU A 399
 EDO  A 820 (-3.8A)
None
EDO  A 820 (-4.0A)
None
None
 1.44A 6chgC-5v1wA:
undetectable		 6chgC-5v1wA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 HIS A 716
ASP A 363
GLU A 720
LYS A 740
LEU A 681
 PO4  A 812 (-3.8A)
None
None
None
None
 1.46A 6gbnB-5v1wA:
undetectable		 6gbnB-5v1wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 HIS A 716
ASP A 363
GLU A 720
LYS A 740
LEU A 681
 PO4  A 812 (-3.8A)
None
None
None
None
 1.48A 6gbnC-5v1wA:
undetectable		 6gbnC-5v1wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 11 VAL A 161
GLY A 177
SER A 180
ALA A 307
VAL A 269
 None
None
None
None
EDO  A 815 (-4.4A)
 1.36A 6hu9A-5v1wA:
0.7
6hu9E-5v1wA:
1.1
6hu9I-5v1wA:
undetectable		 6hu9A-5v1wA:
20.50
6hu9E-5v1wA:
12.35
6hu9I-5v1wA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 0.99A 6hwdV-5v1wA:
undetectable
6hwdb-5v1wA:
undetectable		 6hwdV-5v1wA:
8.06
6hwdb-5v1wA:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		5 / 12 SER A 319
THR A 286
THR A 287
THR A 288
ALA A 317
 None
EDO  A 818 (-4.2A)
None
EDO  A 818 (-4.1A)
None
 1.00A 6hwdH-5v1wA:
undetectable
6hwdN-5v1wA:
undetectable		 6hwdH-5v1wA:
8.06
6hwdN-5v1wA:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v1w GLYCOSIDE HYDROLASE
(Bacillus
halodurans) 		4 / 6 ILE A 734
LEU A 355
TYR A 351
THR A 729
 None
 1.11A 6nmfN-5v1wA:
undetectable
6nmfW-5v1wA:
undetectable		 6nmfN-5v1wA:
21.86
6nmfW-5v1wA:
6.00