SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 8 GLU A 288
LEU A   8
ALA A 259
LEU A 260
 None
 1.04A 1hwiB-5v2iA:
undetectable		 1hwiB-5v2iA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 8 GLU A 288
LEU A   8
ALA A 259
LEU A 260
 None
 1.02A 1hwiC-5v2iA:
undetectable		 1hwiC-5v2iA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 4 ASP A  58
HIS A 178
ARG A  62
GLU A  83
 None
 1.29A 1lqtA-5v2iA:
undetectable		 1lqtA-5v2iA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 LEU A 164
ALA A 199
LEU A 260
VAL A  35
ALA A 167
 None
 1.01A 1sa1A-5v2iA:
undetectable
1sa1B-5v2iA:
undetectable		 1sa1A-5v2iA:
20.39
1sa1B-5v2iA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 LEU A 164
ALA A 199
LEU A 260
VAL A  35
ALA A 167
 None
 1.02A 1sa1C-5v2iA:
undetectable
1sa1D-5v2iA:
undetectable		 1sa1C-5v2iA:
20.39
1sa1D-5v2iA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 5 VAL A  39
GLY A  38
VAL A  35
TRP A  22
 None
 1.15A 1tkqB-5v2iA:
undetectable		 1tkqB-5v2iA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 THR A 152
THR A  10
GLY A 190
GLY A 256
ILE A 187
 None
 1.03A 2b25A-5v2iA:
undetectable		 2b25A-5v2iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY A 214
ALA A 202
THR A 201
ALA A 200
ALA A 235
 None
 1.01A 2gluB-5v2iA:
undetectable		 2gluB-5v2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY A  52
ASP A  44
GLY A 154
ASN A  87
LEU A  65
 None
 0.97A 3eeyB-5v2iA:
undetectable		 3eeyB-5v2iA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY A  52
ASP A  44
GLY A 154
ASN A  87
LEU A  65
 None
 0.91A 3eeyE-5v2iA:
undetectable		 3eeyE-5v2iA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY A  52
ASP A  44
GLY A 154
ASN A  87
LEU A  65
 None
 0.89A 3eeyF-5v2iA:
undetectable		 3eeyF-5v2iA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY A  52
ASP A  44
GLY A 154
ASN A  87
LEU A  65
 None
 0.96A 3eeyJ-5v2iA:
undetectable		 3eeyJ-5v2iA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.10A 4e47A-5v2iA:
undetectable		 4e47A-5v2iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.08A 4e47B-5v2iA:
undetectable		 4e47B-5v2iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.16A 4e47C-5v2iA:
undetectable		 4e47C-5v2iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.09A 4jdsA-5v2iA:
undetectable		 4jdsA-5v2iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.11A 4jdsB-5v2iA:
undetectable		 4jdsB-5v2iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.16A 4jdsC-5v2iA:
undetectable		 4jdsC-5v2iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 ALA A 259
GLY A 198
ILE A  76
MET A  70
GLY A 166
 None
 1.04A 4r29D-5v2iA:
undetectable		 4r29D-5v2iA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 10 GLY A 162
GLU A  72
LEU A  25
ALA A 157
ALA A 199
 None
 1.22A 4wnuD-5v2iA:
undetectable		 4wnuD-5v2iA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY A  52
GLY A  54
LYS A  86
ARG A  40
GLU A  48
 None
 1.19A 4x61A-5v2iA:
undetectable		 4x61A-5v2iA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 9 ILE A 186
GLY A 190
ILE A 210
GLU A 207
ARG A 180
 None
 1.19A 4yp2B-5v2iA:
undetectable		 4yp2B-5v2iA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 ILE A  89
ALA A 167
GLY A 166
GLY A  14
ASN A  18
 None
 1.14A 5ayfA-5v2iA:
undetectable		 5ayfA-5v2iA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 9 ILE A 186
GLY A 190
ILE A 210
GLU A 207
ARG A 180
 None
 1.21A 5cf9B-5v2iA:
undetectable		 5cf9B-5v2iA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		3 / 3 ARG A 180
THR A 170
ASP A  66
 None
 0.95A 5g5gA-5v2iA:
undetectable
5g5gB-5v2iA:
undetectable		 5g5gA-5v2iA:
21.57
5g5gB-5v2iA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 VAL A  91
ALA A  67
VAL A  79
GLY A 190
THR A 201
 None
 1.15A 5igiA-5v2iA:
undetectable		 5igiA-5v2iA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 6 LEU A 123
SER A 128
ARG A  56
GLY A  54
 None
 1.05A 5o4yF-5v2iA:
undetectable		 5o4yF-5v2iA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5v2i GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 7 ILE A 239
GLU A 207
HIS A 205
VAL A 255
 None
 1.08A 6j20A-5v2iA:
undetectable		 6j20A-5v2iA:
20.59