SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		5 / 12 ALA A  65
GLU A  66
LEU A 110
LEU A  52
LEU A  90
 GOL  A 201 (-3.7A)
None
None
None
None
 0.86A 1errB-5v3eA:
undetectable		 1errB-5v3eA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		5 / 9 LEU A  55
GLY A  83
ALA A  10
LEU A  25
LEU A  29
 None
 0.95A 1nr6A-5v3eA:
undetectable		 1nr6A-5v3eA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		4 / 5 VAL A  82
GLY A  83
VAL A  58
TRP A  11
 None
 1.00A 1tkqB-5v3eA:
undetectable		 1tkqB-5v3eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		5 / 12 LEU A  80
GLY A  59
GLY A  83
LEU A  16
GLY A  15
 None
 1.24A 1y4lA-5v3eA:
undetectable		 1y4lA-5v3eA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		5 / 11 GLY A  15
ARG A  84
ILE A 139
LEU A  86
ILE A  57
 None
GOL  A 201 ( 4.9A)
None
GOL  A 201 ( 4.9A)
None
 1.10A 4xumB-5v3eA:
undetectable		 4xumB-5v3eA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		5 / 12 LEU A  80
ALA A  81
VAL A  82
GLU A 106
ALA A 104
 None
 1.12A 5n5dB-5v3eA:
undetectable		 5n5dB-5v3eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 5v3e TRANSCRIPTIONAL
REGULATOR
(Porphyromonas
gingivalis) 		5 / 11 LEU A 102
GLN A  74
GLY A  69
PRO A  88
LEU A  80
 None
 1.27A 6euqA-5v3eA:
undetectable		 6euqA-5v3eA:
undetectable