SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v3n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
ULP2P,TOPOISOMERASE
1-ASSOCIATED FACTOR
2 CHIMERA
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae
x
Saccharomyces
kudriavzevii) 		4 / 7 PHE B  59
TYR A 156
LEU A 157
LYS A 177
 None
 1.17A 1rmtB-5v3nB:
undetectable		 1rmtB-5v3nB:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 119
ALA A 135
SER A 162
THR A 160
 None
 1.02A 3d2tB-5v3nA:
undetectable		 3d2tB-5v3nA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
ULP2P,TOPOISOMERASE
1-ASSOCIATED FACTOR
2 CHIMERA
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae
x
Saccharomyces
kudriavzevii) 		3 / 3 ARG A  85
HIS A  87
SER B  33
 None
 1.00A 4mjwA-5v3nA:
undetectable
4mjwB-5v3nA:
undetectable		 4mjwA-5v3nA:
12.16
4mjwB-5v3nA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
ULP2P,TOPOISOMERASE
1-ASSOCIATED FACTOR
2 CHIMERA
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae
x
Saccharomyces
kudriavzevii) 		3 / 3 SER B  33
ARG A  85
HIS A  87
 None
 1.02A 4mjwA-5v3nB:
undetectable
4mjwB-5v3nB:
undetectable		 4mjwA-5v3nB:
4.84
4mjwB-5v3nB:
4.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 156
TYR A 118
ALA A 176
SER A 178
LEU A 179
 None
 1.12A 4rrxB-5v3nA:
undetectable		 4rrxB-5v3nA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 119
ALA A 135
SER A 162
THR A 160
 None
 0.90A 5bojB-5v3nA:
undetectable		 5bojB-5v3nA:
22.30