SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		4 / 6 TRP A 101
GLY A 128
ILE A 140
PHE A  87
 None
 0.97A 4qogA-5v3sA:
undetectable
4qogB-5v3sA:
undetectable		 4qogA-5v3sA:
20.17
4qogB-5v3sA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 12 TYR A 100
ASP A 111
GLY A  85
LEU A  38
GLY A 107
 None
 1.12A 5i71A-5v3sA:
undetectable		 5i71A-5v3sA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 12 TYR A 100
ASP A 111
GLY A  85
LEU A  38
GLY A 107
 None
 1.13A 5i75A-5v3sA:
undetectable		 5i75A-5v3sA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		4 / 5 ALA A  36
VAL A  33
PHE A  43
ILE A  24
 None
 1.04A 5of1A-5v3sA:
undetectable		 5of1A-5v3sA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		4 / 5 ALA A  36
VAL A  33
PHE A  43
ILE A  24
 None
 1.06A 5of1B-5v3sA:
undetectable		 5of1B-5v3sA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 12 LEU A  38
GLY A  85
GLN A  18
CYH A 103
ASP A 111
 None
 1.27A 6bxlA-5v3sA:
undetectable		 6bxlA-5v3sA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 10 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 1.04A 6ebpB-5v3sA:
undetectable		 6ebpB-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 10 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 1.02A 6ebpC-5v3sA:
undetectable		 6ebpC-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 10 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 0.99A 6ebpD-5v3sA:
undetectable		 6ebpD-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 11 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 1.01A 6ebzA-5v3sA:
undetectable		 6ebzA-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 11 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 1.03A 6ebzB-5v3sA:
undetectable		 6ebzB-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 11 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 1.03A 6ebzC-5v3sA:
undetectable		 6ebzC-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT
(Alcaligenes
faecalis) 		5 / 11 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
 None
 1.02A 6ebzD-5v3sA:
undetectable		 6ebzD-5v3sA:
18.18