SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 5v4q GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 LIGHT
CHAIN
(Homo
sapiens) 		6 / 12 LEU B 450
ASP B 422
THR B 475
GLY B 474
GLY B 473
THR B 381
 None
None
None
8WY  B1102 (-3.6A)
8WY  B1102 (-3.7A)
8WY  B1102 (-2.4A)
 1.40A 2uvnA-5v4qB:
undetectable		 2uvnA-5v4qB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5v4q GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 LIGHT
CHAIN
(Homo
sapiens) 		6 / 12 GLY B 473
ALA B 480
THR B 481
ARG B 503
GLU B 516
ALA B 382
 8WY  B1102 (-3.7A)
None
None
None
None
CL  B1103 (-3.8A)
 1.47A 3g89A-5v4qB:
undetectable		 3g89A-5v4qB:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5v4q GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 LIGHT
CHAIN
(Homo
sapiens) 		6 / 11 GLY B 473
ALA B 480
THR B 481
ARG B 503
GLU B 516
ALA B 382
 8WY  B1102 (-3.7A)
None
None
None
None
CL  B1103 (-3.8A)
 1.34A 3g89B-5v4qB:
undetectable		 3g89B-5v4qB:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5v4q GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 LIGHT
CHAIN
(Homo
sapiens) 		6 / 12 GLY B 473
ALA B 480
THR B 481
ARG B 503
GLU B 516
ALA B 382
 8WY  B1102 (-3.7A)
None
None
None
None
CL  B1103 (-3.8A)
 1.32A 3g8bA-5v4qB:
undetectable		 3g8bA-5v4qB:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5v4q GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 ALA B 472
ILE B 477
ARG B 503
GLY B 470
 CL  B1103 (-3.6A)
None
None
None
 0.91A 3v4tH-5v4qB:
undetectable		 3v4tH-5v4qB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5v4q GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 GLU B 516
GLU B 501
GLU B 500
ARG B 497
 None
 1.17A 4mi4B-5v4qB:
undetectable
4mi4C-5v4qB:
undetectable		 4mi4B-5v4qB:
19.05
4mi4C-5v4qB:
19.05