SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		5 / 12 TYR A 151
VAL A  70
TRP A  59
HIS A  45
LEU A  42
 None
 1.10A 1kiaC-5v51A:
undetectable		 1kiaC-5v51A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		5 / 12 TYR A 151
VAL A  70
TRP A  59
HIS A  45
LEU A  42
 None
 1.11A 1kiaD-5v51A:
undetectable		 1kiaD-5v51A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		5 / 12 TYR A 151
VAL A  70
TRP A  59
HIS A  45
LEU A  42
 None
 1.10A 1nbhB-5v51A:
undetectable		 1nbhB-5v51A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A303_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		4 / 4 ASN A 161
SER A 115
SER A 109
ARG A 114
 SEY  A 201 (-4.7A)
None
None
None
 1.17A 3hlwA-5v51A:
undetectable		 3hlwA-5v51A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		4 / 5 ASN A 161
SER A 115
SER A 109
ARG A 114
 SEY  A 201 (-4.7A)
None
None
None
 1.16A 3hlwB-5v51A:
undetectable		 3hlwB-5v51A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		5 / 12 ASP A 113
SER A 115
THR A 160
ALA A 162
ALA A 123
 None
None
None
SEY  A 201 ( 3.7A)
SEY  A 201 ( 4.0A)
 1.47A 4u15A-5v51A:
undetectable		 4u15A-5v51A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		3 / 3 ASN A  90
PRO A 117
GLN A 119
 None
None
SEY  A 201 (-4.9A)
 0.87A 6jnhA-5v51A:
undetectable		 6jnhA-5v51A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5v51 PR-1 PROTEIN
(Moniliophthora
perniciosa) 		3 / 3 ASN A  90
PRO A 117
GLN A 119
 None
None
SEY  A 201 (-4.9A)
 0.88A 6jogA-5v51A:
undetectable		 6jogA-5v51A:
19.90