SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v52'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		4 / 6 GLY A  90
PRO A  89
ILE A  42
GLY A  92
 None
 0.87A 2jkjA-5v52A:
undetectable		 2jkjA-5v52A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		4 / 6 GLY A  90
PRO A  89
ILE A  42
GLY A  92
 None
 0.87A 2jkjB-5v52A:
undetectable		 2jkjB-5v52A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		4 / 6 GLY A  90
PRO A  89
ILE A  42
GLY A  92
 None
 0.87A 2jkjC-5v52A:
undetectable		 2jkjC-5v52A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		5 / 10 ILE A  77
ALA A  67
ILE A  33
LEU A  95
ILE A  27
 None
 1.19A 3prsA-5v52A:
undetectable		 3prsA-5v52A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		3 / 3 GLU A  60
THR A 117
HIS A 111
 None
 0.82A 4q15A-5v52A:
undetectable		 4q15A-5v52A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		3 / 3 GLU A  60
THR A 117
HIS A 111
 None
 0.81A 4q15B-5v52A:
undetectable		 4q15B-5v52A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		5 / 11 GLY A  90
ALA A  67
ILE A  77
LEU A  95
ILE A  42
 None
 0.84A 4xumB-5v52A:
undetectable		 4xumB-5v52A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		3 / 3 GLU A  60
THR A 117
HIS A 111
 None
 0.74A 4ydqB-5v52A:
undetectable		 4ydqB-5v52A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		5 / 10 LEU A  93
GLY A  88
GLY A  90
VAL A  57
ALA A  67
 None
 1.05A 5o96E-5v52A:
undetectable
5o96F-5v52A:
undetectable		 5o96E-5v52A:
20.08
5o96F-5v52A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5v52 T-CELL
IMMUNORECEPTOR WITH
IG AND ITIM DOMAINS
(Homo
sapiens) 		5 / 10 LEU A  93
GLY A  88
GLY A  90
VAL A  57
ALA A  67
 None
 1.06A 5o96G-5v52A:
undetectable
5o96H-5v52A:
undetectable		 5o96G-5v52A:
20.08
5o96H-5v52A:
20.08