SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5v5w MAM
DOMAIN-CONTAINING
GLYCOSYLPHOSPHATIDYL
INOSITOL ANCHOR
PROTEIN 1
(Homo
sapiens) 		4 / 7 VAL A 153
LEU A 204
TYR A 209
PHE A 231
 None
 0.98A 3qeoB-5v5wA:
undetectable		 3qeoB-5v5wA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5v5w MAM
DOMAIN-CONTAINING
GLYCOSYLPHOSPHATIDYL
INOSITOL ANCHOR
PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A 192
THR A 196
ARG A 156
 None
 0.78A 5wm2A-5v5wA:
undetectable		 5wm2A-5v5wA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5v5w MAM
DOMAIN-CONTAINING
GLYCOSYLPHOSPHATIDYL
INOSITOL ANCHOR
PROTEIN 1
(Homo
sapiens) 		4 / 4 ASP A 130
ILE A 224
PRO A 225
LEU A 129
 None
 1.45A 6mkeB-5v5wA:
undetectable		 6mkeB-5v5wA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5v5w MAM
DOMAIN-CONTAINING
GLYCOSYLPHOSPHATIDYL
INOSITOL ANCHOR
PROTEIN 1
(Homo
sapiens) 		4 / 4 ASP A 130
ILE A 224
PRO A 225
LEU A 129
 None
 1.45A 6mkeA-5v5wA:
undetectable		 6mkeA-5v5wA:
19.69