SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 5v5x MCG133388, ISOFORM
CRA_Y
(Mus
musculus) 		5 / 12 VAL A 339
ILE A 315
ILE A 390
ILE A 362
VAL A 350
 None
 1.04A 1qhsA-5v5xA:
undetectable		 1qhsA-5v5xA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5v5x MCG133388, ISOFORM
CRA_Y
(Mus
musculus) 		4 / 8 LYS A 300
ASP A 286
LEU A 252
SER A 297
 None
 1.00A 3lm8A-5v5xA:
undetectable
3lm8C-5v5xA:
undetectable		 3lm8A-5v5xA:
19.09
3lm8C-5v5xA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5v5x MCG133388, ISOFORM
CRA_Y
(Mus
musculus) 		3 / 3 GLN A 501
THR A 499
ASN A 513
 None
None
NAG  A 716 (-1.8A)
 0.76A 3v4tE-5v5xA:
undetectable		 3v4tE-5v5xA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5v5x MCG133388, ISOFORM
CRA_Y
(Mus
musculus) 		4 / 8 ASP A 489
ASP A 616
ASN A 526
GLU A 431
 CA  A 707 (-3.1A)
CA  A 709 (-3.5A)
CA  A 707 (-4.2A)
CA  A 708 ( 2.8A)
 1.12A 4gkhC-5v5xA:
undetectable
4gkhK-5v5xA:
undetectable		 4gkhC-5v5xA:
19.95
4gkhK-5v5xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5v5x MCG133388, ISOFORM
CRA_Y
(Mus
musculus) 		4 / 8 ASP A 489
ASP A 616
ASN A 526
GLU A 431
 CA  A 707 (-3.1A)
CA  A 709 (-3.5A)
CA  A 707 (-4.2A)
CA  A 708 ( 2.8A)
 1.08A 4gkiE-5v5xA:
undetectable
4gkiG-5v5xA:
undetectable		 4gkiE-5v5xA:
19.95
4gkiG-5v5xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5v5x MCG133388, ISOFORM
CRA_Y
(Mus
musculus) 		4 / 6 GLY A 436
PHE A 488
ILE A 439
PHE A 496
 None
 1.09A 4qogA-5v5xA:
undetectable
4qogB-5v5xA:
undetectable		 4qogA-5v5xA:
20.36
4qogB-5v5xA:
20.36