SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 7 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.06A 2eikA-5v6bA:
undetectable
2eikJ-5v6bA:
undetectable		 2eikA-5v6bA:
17.68
2eikJ-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.07A 2eimJ-5v6bA:
undetectable		 2eimJ-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.01A 2eimW-5v6bA:
undetectable		 2eimW-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		5 / 11 ILE A 157
SER A 173
ILE A 172
VAL A 134
LEU A 209
 None
 1.02A 2kawA-5v6bA:
11.2		 2kawA-5v6bA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 LEU A 283
ASP A 269
ALA A 284
ILE A 278
 None
 1.16A 2qhfA-5v6bA:
undetectable		 2qhfA-5v6bA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 6 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.10A 2zxwA-5v6bA:
undetectable
2zxwJ-5v6bA:
undetectable		 2zxwA-5v6bA:
17.68
2zxwJ-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.07A 3ag2J-5v6bA:
undetectable		 3ag2J-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.16A 3ag4J-5v6bA:
undetectable		 3ag4J-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 6 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.08A 3asoA-5v6bA:
undetectable
3asoJ-5v6bA:
undetectable		 3asoA-5v6bA:
17.68
3asoJ-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 VAL A 134
LEU A 209
LEU A 211
ILE A 166
 None
 0.84A 4a9jA-5v6bA:
undetectable		 4a9jA-5v6bA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 VAL A 134
LEU A 209
LEU A 211
ILE A 166
 None
 0.88A 4a9jB-5v6bA:
undetectable		 4a9jB-5v6bA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		5 / 12 LEU A 145
LEU A 198
LEU A 201
ILE A 157
VAL A 134
 None
 0.93A 4f4dB-5v6bA:
undetectable		 4f4dB-5v6bA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		5 / 10 LEU A 145
LEU A 198
LEU A 201
ILE A 157
VAL A 134
 None
 1.01A 4mk4A-5v6bA:
undetectable		 4mk4A-5v6bA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.17A 5w97J-5v6bA:
undetectable		 5w97J-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.20A 5wauJ-5v6bA:
undetectable		 5wauJ-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.17A 5x1fW-5v6bA:
undetectable		 5x1fW-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.32A 5z86J-5v6bA:
undetectable		 5z86J-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 6 GLU A 179
ARG A 131
GLU A 213
LYS A 128
 None
 1.08A 6an0A-5v6bA:
undetectable		 6an0A-5v6bA:
18.89