SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 5 ASP A 841
ASP A 882
ALA A 880
LEU A 843
 None
 0.93A 1nh8A-5v6cA:
undetectable		 1nh8A-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 8 PHE A 953
GLY A 952
PRO A 824
GLY A 822
 None
 0.93A 2y6rB-5v6cA:
undetectable		 2y6rB-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 7 VAL A 889
MET A 844
ILE A 855
ILE A 852
 None
 0.99A 3hgxA-5v6cA:
undetectable		 3hgxA-5v6cA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 8 ARG A 876
SER A 918
PHE A 850
TYR A 921
 None
None
GOL  A1001 (-4.7A)
None
 0.92A 3jq7B-5v6cA:
undetectable		 3jq7B-5v6cA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 6 ARG A 876
SER A 918
PHE A 850
TYR A 921
 None
None
GOL  A1001 (-4.7A)
None
 0.89A 3jqaA-5v6cA:
undetectable		 3jqaA-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 6 ARG A 876
SER A 918
PHE A 850
TYR A 921
 None
None
GOL  A1001 (-4.7A)
None
 0.91A 3jqaB-5v6cA:
undetectable		 3jqaB-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 6 ARG A 876
SER A 918
PHE A 850
TYR A 921
 None
None
GOL  A1001 (-4.7A)
None
 0.90A 3jqaC-5v6cA:
undetectable		 3jqaC-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 6 ARG A 876
SER A 918
PHE A 850
TYR A 921
 None
None
GOL  A1001 (-4.7A)
None
 0.87A 3jqaD-5v6cA:
undetectable		 3jqaD-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		4 / 8 THR A 890
SER A 886
THR A 929
VAL A 927
 None
 0.83A 4ik7B-5v6cA:
undetectable		 4ik7B-5v6cA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		5 / 12 THR A 831
GLY A 827
GLY A 952
SER A 891
ALA A 922
 None
 0.97A 4uciA-5v6cA:
undetectable		 4uciA-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		5 / 12 THR A 831
GLY A 827
GLY A 952
SER A 891
ALA A 922
 None
 0.97A 4uciB-5v6cA:
undetectable		 4uciB-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		5 / 12 THR A 831
GLY A 827
GLY A 952
SER A 891
ALA A 922
 None
 0.93A 4uckA-5v6cA:
undetectable		 4uckA-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		5 / 12 THR A 831
GLY A 827
GLY A 952
SER A 891
ALA A 922
 None
 0.93A 4uckB-5v6cA:
undetectable		 4uckB-5v6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 5v6c HEMOLYSIN-RELATED
PROTEIN
(Vibrio
cholerae) 		5 / 12 PHE A 953
ILE A 855
ILE A 941
ILE A 879
VAL A 889
 None
 0.96A 5uvmB-5v6cA:
undetectable		 5uvmB-5v6cA:
20.00