SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5v6d NUCLEOSIDE
DIPHOSPHATE KINASE
(Neisseria
gonorrhoeae) 		4 / 6 MET A  67
VAL A  64
LEU A  63
PHE A  59
 None
None
CIT  A 201 ( 4.7A)
CIT  A 201 (-4.2A)
 0.95A 1x8vA-5v6dA:
undetectable		 1x8vA-5v6dA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 5v6d NUCLEOSIDE
DIPHOSPHATE KINASE
(Neisseria
gonorrhoeae) 		4 / 8 MET A  67
LEU A  63
ARG A 104
GLY A 118
 None
CIT  A 201 ( 4.7A)
CIT  A 201 (-2.9A)
None
 1.11A 2qd5A-5v6dA:
undetectable		 2qd5A-5v6dA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5v6d NUCLEOSIDE
DIPHOSPHATE KINASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A  23
ALA A 115
ALA A  14
ASN A  18
PHE A 107
ALA A 108
 None
 1.38A 3e00A-5v6dA:
undetectable		 3e00A-5v6dA:
16.70