SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5v6e PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 LEU A 283
ASP A 269
ALA A 284
ILE A 278
 None
 1.17A 2qhfA-5v6eA:
undetectable		 2qhfA-5v6eA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5v6e PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.37A 3ag2J-5v6eA:
undetectable		 3ag2J-5v6eA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v6e PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1
(Mus
musculus) 		4 / 5 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.45A 5x1bW-5v6eA:
undetectable		 5x1bW-5v6eA:
20.83