SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 5v6h PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Mus
musculus) 		4 / 8 PHE A 299
LEU A 254
LEU A 290
LEU A 286
 None
 0.89A 2bfpA-5v6hA:
undetectable		 2bfpA-5v6hA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5v6h PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Mus
musculus) 		4 / 7 LEU A 253
PHE A 299
MET A 269
THR A 268
 None
 1.21A 2zxwN-5v6hA:
undetectable
2zxwW-5v6hA:
undetectable		 2zxwN-5v6hA:
9.94
2zxwW-5v6hA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5v6h PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
UNCONVENTIONAL
MYOSIN-VI
(Mus
musculus) 		4 / 6 ASP A 251
TYR B1059
TYR B1089
LEU B1086
 None
 1.38A 5bmvB-5v6hA:
undetectable		 5bmvB-5v6hA:
10.80