SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		4 / 8 HIS A 144
GLY A 171
GLY A 147
LEU A 102
 None
 0.73A 1aegA-5v76A:
undetectable		 1aegA-5v76A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 LEU A  37
VAL A  36
SER A  35
SER A  24
VAL A  46
 None
 1.09A 1db1A-5v76A:
undetectable		 1db1A-5v76A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 LEU A  37
VAL A  36
SER A  35
SER A  24
VAL A  46
 None
 1.13A 1ie9A-5v76A:
undetectable		 1ie9A-5v76A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 GLY A  87
VAL A   8
LEU A   9
ALA A  34
THR A  50
 None
 0.96A 1jipA-5v76A:
undetectable		 1jipA-5v76A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 LEU A 176
ALA A 188
ALA A 159
ALA A 156
VAL A 167
 None
 1.25A 1rbpA-5v76A:
undetectable		 1rbpA-5v76A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 LEU A  37
VAL A  36
SER A  35
SER A  24
LEU A  94
 None
 1.05A 2hc4A-5v76A:
undetectable		 2hc4A-5v76A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 12 LEU A  37
VAL A  36
SER A  35
SER A  24
LEU A  94
 None
 1.02A 2zlcA-5v76A:
undetectable		 2zlcA-5v76A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		5 / 9 LEU A  63
PHE A 170
THR A   7
ARG A 175
LEU A 141
 None
 1.15A 3nxuB-5v76A:
undetectable		 3nxuB-5v76A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		4 / 4 LEU A 164
GLY A 129
LEU A 165
GLU A 166
 None
 1.05A 3tgvB-5v76A:
undetectable		 3tgvB-5v76A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		4 / 5 GLN A  21
THR A 169
LEU A   9
LEU A  12
 None
 0.95A 4lvcB-5v76A:
undetectable		 4lvcB-5v76A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		4 / 4 ALA A 149
ALA A 152
ALA A 153
ALA A 156
 None
 0.13A 4oaeA-5v76A:
2.1		 4oaeA-5v76A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5v76 MICROCOMPARTMENTS
PROTEIN
(Haliangium
ochraceum) 		3 / 3 ARG A   4
PRO A 145
ASN A 204
 None
 0.98A 5jwaA-5v76A:
undetectable
5jwaH-5v76A:
undetectable		 5jwaA-5v76A:
16.89
5jwaH-5v76A:
16.89