SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5v77 UNCHARACTERIZED
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A  98
ILE A  93
LEU A  11
ILE A  69
PHE A  47
 None
 1.08A 1bsxA-5v77A:
undetectable		 1bsxA-5v77A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5v77 UNCHARACTERIZED
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A  98
ILE A  93
LEU A  11
ILE A  69
PHE A  47
 None
 1.08A 1bsxB-5v77A:
undetectable		 1bsxB-5v77A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5v77 UNCHARACTERIZED
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A  98
ILE A  93
LEU A  11
ILE A  69
PHE A  47
 None
 1.07A 1xzxX-5v77A:
undetectable		 1xzxX-5v77A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5v77 UNCHARACTERIZED
PROTEIN
(Neisseria
gonorrhoeae) 		3 / 3 ASP A  50
ASP A  86
ASN A  53
 None
 0.63A 2bm9D-5v77A:
undetectable		 2bm9D-5v77A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5v77 UNCHARACTERIZED
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A  98
ILE A  93
LEU A  11
ILE A  69
PHE A  47
 None
 0.99A 3gwsX-5v77A:
undetectable		 3gwsX-5v77A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 5v77 UNCHARACTERIZED
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 11 PHE A  65
ILE A  69
ILE A  93
ILE A  83
PHE A  27
 None
 1.17A 5hw8D-5v77A:
undetectable		 5hw8D-5v77A:
25.18