SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASP A1091
ASP A1096
ASP A1084
 None
 0.62A 1eizA-5v88A:
undetectable		 1eizA-5v88A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASP A1091
ASP A1096
ASP A1084
 None
 0.60A 1ej0A-5v88A:
undetectable		 1ej0A-5v88A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 PHE A 153
VAL A  87
LEU A 118
ALA A 129
 None
 1.08A 2e1qA-5v88A:
undetectable		 2e1qA-5v88A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 VAL A1244
GLU A1232
GLU A1245
 None
 0.77A 2nv4A-5v88A:
undetectable		 2nv4A-5v88A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 LEU A1093
LEU A1103
MET A1126
TYR A1072
 None
 1.13A 2w8yA-5v88A:
undetectable		 2w8yA-5v88A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.05A 2xytE-5v88A:
undetectable		 2xytE-5v88A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.00A 2xytH-5v88A:
undetectable		 2xytH-5v88A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.03A 2xytI-5v88A:
undetectable		 2xytI-5v88A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 5 PHE A   4
ILE A 100
MET A   1
PHE A 104
 None
 1.21A 3octA-5v88A:
1.7		 3octA-5v88A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.24A 3peoG-5v88A:
undetectable		 3peoG-5v88A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ILE A  50
VAL A  71
GLN A  -2
LEU A  -5
LEU A  -8
 None
 1.11A 4qztA-5v88A:
undetectable		 4qztA-5v88A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 MET A   1
ALA A  97
GLU A  11
ILE A   9
VAL A 149
 None
 1.31A 5vlmB-5v88A:
undetectable		 5vlmB-5v88A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ARG A1189
PHE A1160
LEU A1148
 None
 0.45A 5x1bC-5v88A:
undetectable		 5x1bC-5v88A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 LYS A1155
GLN A1159
LEU A1186
PHE A1190
 None
 1.25A 6nmpC-5v88A:
undetectable
6nmpJ-5v88A:
undetectable		 6nmpC-5v88A:
20.73
6nmpJ-5v88A:
10.65