SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 257
ASN A 254
TRP A 275
 None
 1.09A 1r15C-5v89A:
undetectable		 1r15C-5v89A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 257
ASN A 254
TRP A 275
 None
 1.04A 1r15D-5v89A:
undetectable		 1r15D-5v89A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 257
ASN A 254
TRP A 275
 None
 1.07A 1r15E-5v89A:
undetectable		 1r15E-5v89A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 257
ASN A 254
TRP A 275
 None
 1.11A 1r15F-5v89A:
undetectable		 1r15F-5v89A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		4 / 8 GLU A 284
TYR A 244
PHE A 238
GLN A 241
 None
 1.04A 3mjrD-5v89A:
undetectable		 3mjrD-5v89A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		4 / 8 LEU A 224
TYR A 197
VAL A 139
LEU A 212
 None
 1.01A 4l1xA-5v89A:
undetectable		 4l1xA-5v89A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 5v89 DCN1-LIKE PROTEIN 4
(Homo
sapiens) 		4 / 7 ILE A 262
PHE A 258
TRP A 275
ASP A 280
 None
 1.40A 5nr3A-5v89A:
undetectable		 5nr3A-5v89A:
23.00