SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v8d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 5v8d BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		3 / 3 PHE C 274
TYR C 212
PRO C 344
 None
 1.13A 1mcnA-5v8dC:
undetectable
1mcnB-5v8dC:
undetectable
1mcnP-5v8dC:
undetectable		 1mcnA-5v8dC:
18.21
1mcnB-5v8dC:
18.21
1mcnP-5v8dC:
0.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 5v8d BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 8 ASP C 336
SER C 383
TYR C 196
HIS C 201
 SO4  C 403 (-3.9A)
None
None
SO4  C 403 (-3.8A)
 1.28A 2bteA-5v8dC:
undetectable		 2bteA-5v8dC:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5v8d BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 5 TYR C 165
ILE C 177
LEU C 179
LYS C 178
 None
 1.11A 3sueC-5v8dC:
undetectable		 3sueC-5v8dC:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5v8d BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		3 / 3 THR C 280
VAL C 288
GLU C 317
 None
 0.68A 3v4tA-5v8dC:
undetectable
3v4tD-5v8dC:
undetectable		 3v4tA-5v8dC:
21.95
3v4tD-5v8dC:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5v8d BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 6 ILE C 295
LEU C 346
HIS C 345
PHE C 137
 None
 0.88A 5vkqA-5v8dC:
undetectable
5vkqB-5v8dC:
undetectable		 5vkqA-5v8dC:
11.70
5vkqB-5v8dC:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5v8d BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 6 PHE C 137
ILE C 295
LEU C 346
HIS C 345
 None
 0.88A 5vkqA-5v8dC:
undetectable
5vkqD-5v8dC:
undetectable		 5vkqA-5v8dC:
11.70
5vkqD-5v8dC:
11.70